Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB6   Type   Machinery gene
Locus tag   HPAKL86_RS00095 Genome accession   NC_019563
Coordinates   11749..12804 (-) Length   351 a.a.
NCBI ID   WP_015086520.1    Uniprot ID   K7Y7P6
Organism   Helicobacter pylori Aklavik86     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 6749..17804
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPAKL86_RS00070 (HPAKL86_00045) - 7286..8698 (-) 1413 WP_015086515.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  HPAKL86_RS00075 (HPAKL86_00050) comB10 8764..9900 (-) 1137 WP_015086516.1 DNA type IV secretion system protein ComB10 Machinery gene
  HPAKL86_RS00080 (HPAKL86_00055) comB9 9893..10858 (-) 966 WP_015086517.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  HPAKL86_RS00085 (HPAKL86_00060) comB8 10858..11601 (-) 744 WP_015086518.1 type IV secretion system protein Machinery gene
  HPAKL86_RS00090 (HPAKL86_00065) comB7 11598..11723 (-) 126 WP_015086519.1 hypothetical protein Machinery gene
  HPAKL86_RS00095 (HPAKL86_00070) comB6 11749..12804 (-) 1056 WP_015086520.1 P-type conjugative transfer protein TrbL Machinery gene
  HPAKL86_RS00100 (HPAKL86_00075) - 12812..13807 (-) 996 WP_015086521.1 PDZ domain-containing protein -
  HPAKL86_RS00105 (HPAKL86_00080) - 13807..14100 (-) 294 WP_000347917.1 YbaB/EbfC family nucleoid-associated protein -
  HPAKL86_RS00110 (HPAKL86_00085) panD 14111..14461 (-) 351 WP_015086522.1 aspartate 1-decarboxylase -
  HPAKL86_RS00115 (HPAKL86_00090) - 14451..16670 (-) 2220 WP_015086523.1 AAA family ATPase -
  HPAKL86_RS00120 (HPAKL86_00095) - 16670..16945 (-) 276 WP_015086524.1 ATP-dependent Clp protease adaptor ClpS -
  HPAKL86_RS00125 (HPAKL86_00100) - 16976..17389 (-) 414 WP_015086525.1 universal stress protein -
  HPAKL86_RS00130 (HPAKL86_00105) - 17497..17784 (+) 288 WP_015086526.1 hypothetical protein -

Sequence

Protein


Download         Length: 351 a.a.        Molecular weight: 39850.73 Da        Isoelectric Point: 9.0419

>NTDB_id=54583 HPAKL86_RS00095 WP_015086520.1 11749..12804(-) (comB6) [Helicobacter pylori Aklavik86]
MKNDAYEIILSWFITPLTAILGRFAEFFLYTLHAQLVFNSVVALAFMLFAYRSLKEQNFFSASALTEALWFVGFFALFNY
ALKNPMRFYEFFQNAIFIAPNMITQSLSQSLSNFSNHALSLDFIFNHGFYALSFISDLSHNEMSVWLFLSILQGLFLSVL
FAIIILVYLEVHVWCSLGVLFLAFGFFKTWRSVVVACLKKCFALGFYKPFLLLVGFLNVSVTKALIDAHMQEKQDLSLLL
VVALFLCCVFIIGVPFFINALFRVQNSFKETYKLATNLSANLSQNALNSLQYITTSPASSSVSSSMSGSVSKEKETHSPT
FKVETTQLDVKIPNFKQKKVKKDTINPKHEN

Nucleotide


Download         Length: 1056 bp        

>NTDB_id=54583 HPAKL86_RS00095 WP_015086520.1 11749..12804(-) (comB6) [Helicobacter pylori Aklavik86]
ATGAAAAATGACGCTTATGAAATTATCCTTTCTTGGTTTATCACGCCTCTCACAGCGATTTTAGGGCGTTTCGCTGAATT
TTTTCTCTACACCTTGCATGCGCAATTGGTGTTTAATAGCGTGGTCGCTTTGGCGTTCATGCTCTTTGCTTATAGGAGTT
TGAAAGAACAGAATTTTTTCAGCGCTAGCGCGCTAACGGAAGCGTTATGGTTTGTGGGGTTTTTTGCGCTTTTTAACTAC
GCTTTAAAAAATCCCATGCGTTTTTATGAATTTTTCCAAAACGCTATTTTTATTGCACCTAACATGATCACACAAAGCCT
CTCTCAAAGCTTGAGCAACTTTTCTAACCATGCGCTTTCTTTAGATTTTATCTTTAATCATGGTTTTTATGCCCTTAGTT
TTATCAGCGATTTGAGCCATAATGAAATGTCTGTGTGGCTTTTTTTAAGCATTTTGCAAGGGCTTTTTTTGAGCGTGCTG
TTTGCGATCATCATTTTAGTGTATTTAGAAGTGCATGTGTGGTGCTCTTTGGGGGTGCTGTTTTTAGCGTTTGGGTTTTT
TAAAACCTGGAGGAGCGTTGTGGTTGCGTGCTTAAAAAAATGCTTCGCTCTTGGGTTTTACAAGCCTTTTTTATTGTTGG
TGGGGTTTTTGAATGTGTCGGTTACTAAGGCTTTAATAGACGCTCATATGCAAGAAAAACAAGACTTAAGCCTTTTATTG
GTGGTGGCGTTATTTTTGTGTTGCGTTTTTATCATAGGCGTGCCTTTTTTCATCAACGCTTTGTTTAGGGTGCAAAACAG
CTTTAAAGAAACTTACAAACTCGCTACCAATTTGAGCGCCAACCTCAGCCAAAACGCCCTTAATTCCTTGCAATATATCA
CGACCTCACCCGCTTCCTCTAGCGTTTCTTCTTCTATGAGCGGAAGCGTCTCTAAAGAAAAAGAAACGCATTCCCCCACA
TTCAAGGTAGAAACCACTCAATTAGATGTAAAAATCCCAAATTTCAAGCAAAAAAAGGTTAAAAAGGATACAATAAATCC
AAAGCATGAAAATTAA

Domains

Predicted by InterproScan.

TrbL/VirB6 plasmid conjugal transfer protein (TrbL)

(44-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB K7Y7P6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB6 Helicobacter pylori 26695

96.857

99.715

0.966

Multiple sequence alignment