Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   HPAKL86_RS00085 Genome accession   NC_019563
Coordinates   10858..11601 (-) Length   247 a.a.
NCBI ID   WP_015086518.1    Uniprot ID   K7Y678
Organism   Helicobacter pylori Aklavik86     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 5858..16601
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPAKL86_RS00065 (HPAKL86_00040) gmd 6113..7258 (-) 1146 WP_015086514.1 GDP-mannose 4,6-dehydratase -
  HPAKL86_RS00070 (HPAKL86_00045) - 7286..8698 (-) 1413 WP_015086515.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  HPAKL86_RS00075 (HPAKL86_00050) comB10 8764..9900 (-) 1137 WP_015086516.1 DNA type IV secretion system protein ComB10 Machinery gene
  HPAKL86_RS00080 (HPAKL86_00055) comB9 9893..10858 (-) 966 WP_015086517.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  HPAKL86_RS00085 (HPAKL86_00060) comB8 10858..11601 (-) 744 WP_015086518.1 type IV secretion system protein Machinery gene
  HPAKL86_RS00090 (HPAKL86_00065) comB7 11598..11723 (-) 126 WP_015086519.1 hypothetical protein Machinery gene
  HPAKL86_RS00095 (HPAKL86_00070) comB6 11749..12804 (-) 1056 WP_015086520.1 P-type conjugative transfer protein TrbL Machinery gene
  HPAKL86_RS00100 (HPAKL86_00075) - 12812..13807 (-) 996 WP_015086521.1 PDZ domain-containing protein -
  HPAKL86_RS00105 (HPAKL86_00080) - 13807..14100 (-) 294 WP_000347917.1 YbaB/EbfC family nucleoid-associated protein -
  HPAKL86_RS00110 (HPAKL86_00085) panD 14111..14461 (-) 351 WP_015086522.1 aspartate 1-decarboxylase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28659.92 Da        Isoelectric Point: 8.9830

>NTDB_id=54581 HPAKL86_RS00085 WP_015086518.1 10858..11601(-) (comB8) [Helicobacter pylori Aklavik86]
MKEKPFNSEQLAFLEELLSHQEKHLENKLSGFSVSDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIVAKLMNENKLVYEKRYKIVMSYLFDTPDFDYASMPKNPTGFKITRYSITEI
APTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=54581 HPAKL86_RS00085 WP_015086518.1 10858..11601(-) (comB8) [Helicobacter pylori Aklavik86]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAGTTGGCTTTTTTAGAAGAGCTTCTAAGCCACCAAGAAAAGCACTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAGTGATTTGGACATGCAAAGCGTGTTCAGACTGGAGAGGAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGCTTGATGAGTTTTATCGCTCTTGTTTTAGCGATTGTGTTAATCAGTGTTCTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGGGAGAGCATTAATCGCATTGATGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAGATTTGATTAAAACCCAAAACAGCATTTAT
GCGCAAAGTCATTTGGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
CTCTATTGTGGCTAAACTCATGAACGAAAACAAACTGGTGTATGAAAAGCGTTATAAAATCGTGATGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAATCACTCGCTACAGCATCACTGAAATT
GCGCCGACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB K7Y678

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

96.356

100

0.964

Multiple sequence alignment