Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   J0J35_RS10615 Genome accession   NZ_CP071301
Coordinates   2161056..2161739 (+) Length   227 a.a.
NCBI ID   WP_019292408.1    Uniprot ID   A0A139MDU9
Organism   Lactococcus sp. LG606     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 2156056..2166739
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J0J35_RS10605 (J0J35_10605) rpoC 2156161..2159808 (+) 3648 WP_206916913.1 DNA-directed RNA polymerase subunit beta' -
  J0J35_RS10610 (J0J35_10610) - 2159901..2160809 (-) 909 WP_206916916.1 diacylglycerol kinase family protein -
  J0J35_RS10615 (J0J35_10615) mecA 2161056..2161739 (+) 684 WP_019292408.1 adaptor protein MecA Regulator
  J0J35_RS10620 (J0J35_10620) - 2161743..2162999 (+) 1257 WP_019292407.1 glycosyltransferase family 4 protein -
  J0J35_RS10625 (J0J35_10625) sufC 2163077..2163847 (+) 771 WP_017368843.1 Fe-S cluster assembly ATPase SufC -
  J0J35_RS10630 (J0J35_10630) sufD 2163919..2165175 (+) 1257 WP_206916918.1 Fe-S cluster assembly protein SufD -
  J0J35_RS10635 (J0J35_10635) - 2165175..2166386 (+) 1212 WP_206916919.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 26254.39 Da        Isoelectric Point: 4.0031

>NTDB_id=544828 J0J35_RS10615 WP_019292408.1 2161056..2161739(+) (mecA) [Lactococcus sp. LG606]
MQYEEINEKTIKISLTFQDLVDHDVKLSDFFTNQSMVENLFYELVEELGLEERFSSGLLTFQIQPFPKGVNIIVTEENID
IDPNNLPDDPEEFEQLMTDFFGRVEDLKQNGGTMADTSTTETKETKVENKPDPDFVFYSLEFENMSQLLTAVKNVKIDAE
ESELYSYEDKFYLIILDNQKSKGKTAVSSMRARMLEYGQETINSRETLQEYGEILINTRALEVLSKI

Nucleotide


Download         Length: 684 bp        

>NTDB_id=544828 J0J35_RS10615 WP_019292408.1 2161056..2161739(+) (mecA) [Lactococcus sp. LG606]
ATGCAATATGAAGAAATAAACGAAAAAACGATAAAGATTAGCCTAACCTTTCAAGATTTGGTTGATCATGATGTCAAACT
CTCTGATTTTTTTACGAACCAGTCAATGGTTGAAAATCTTTTTTATGAATTAGTAGAAGAACTAGGACTTGAGGAAAGGT
TCTCATCAGGACTTTTAACTTTCCAAATTCAACCTTTCCCTAAAGGGGTGAATATTATTGTTACTGAAGAAAATATTGAT
ATTGATCCCAATAATCTCCCTGATGATCCCGAAGAATTTGAGCAGCTTATGACGGATTTCTTTGGACGTGTGGAAGATTT
AAAACAAAATGGCGGAACAATGGCAGATACAAGTACAACTGAAACAAAAGAAACAAAAGTAGAAAATAAACCAGATCCAG
ATTTTGTCTTCTATTCTCTAGAATTTGAAAACATGTCTCAACTTTTGACAGCAGTAAAAAATGTTAAAATTGATGCAGAG
GAATCTGAACTTTATAGCTATGAAGATAAGTTTTATTTGATTATTTTGGACAATCAAAAGTCAAAAGGAAAGACAGCAGT
AAGTTCGATGCGTGCTCGAATGTTAGAATACGGACAGGAAACAATCAACAGTCGCGAAACACTACAAGAATACGGCGAGA
TACTAATCAATACACGTGCTTTGGAAGTTCTCTCAAAAATTTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-224)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A139MDU9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Lactococcus lactis subsp. cremoris KW2

54.077

100

0.555
  mecA Lactococcus lactis subsp. lactis strain DGCC12653

54.077

100

0.555