Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   J0J33_RS04330 Genome accession   NZ_CP071295
Coordinates   875028..875711 (+) Length   227 a.a.
NCBI ID   WP_019292408.1    Uniprot ID   A0A139MDU9
Organism   Lactococcus sp. LG1267     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 870028..880711
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J0J33_RS04320 (J0J33_04320) rpoC 870133..873780 (+) 3648 WP_206888273.1 DNA-directed RNA polymerase subunit beta' -
  J0J33_RS04325 (J0J33_04325) - 873873..874781 (-) 909 WP_206888275.1 diacylglycerol kinase family protein -
  J0J33_RS04330 (J0J33_04330) mecA 875028..875711 (+) 684 WP_019292408.1 adaptor protein MecA Regulator
  J0J33_RS04335 (J0J33_04335) - 875715..876971 (+) 1257 WP_019293600.1 glycosyltransferase family 4 protein -
  J0J33_RS04340 (J0J33_04340) sufC 877049..877819 (+) 771 WP_206921792.1 Fe-S cluster assembly ATPase SufC -
  J0J33_RS04345 (J0J33_04345) sufD 877891..879147 (+) 1257 WP_019293599.1 Fe-S cluster assembly protein SufD -
  J0J33_RS04350 (J0J33_04350) - 879147..880358 (+) 1212 WP_019292404.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 26254.39 Da        Isoelectric Point: 4.0031

>NTDB_id=544723 J0J33_RS04330 WP_019292408.1 875028..875711(+) (mecA) [Lactococcus sp. LG1267]
MQYEEINEKTIKISLTFQDLVDHDVKLSDFFTNQSMVENLFYELVEELGLEERFSSGLLTFQIQPFPKGVNIIVTEENID
IDPNNLPDDPEEFEQLMTDFFGRVEDLKQNGGTMADTSTTETKETKVENKPDPDFVFYSLEFENMSQLLTAVKNVKIDAE
ESELYSYEDKFYLIILDNQKSKGKTAVSSMRARMLEYGQETINSRETLQEYGEILINTRALEVLSKI

Nucleotide


Download         Length: 684 bp        

>NTDB_id=544723 J0J33_RS04330 WP_019292408.1 875028..875711(+) (mecA) [Lactococcus sp. LG1267]
ATGCAATACGAAGAAATAAACGAAAAAACGATAAAGATTAGCCTAACCTTTCAAGATTTGGTTGATCATGATGTCAAACT
CTCTGATTTTTTTACAAATCAGTCAATGGTTGAAAATCTTTTTTATGAATTAGTAGAAGAACTAGGACTTGAGGAAAGGT
TCTCATCAGGACTTTTAACTTTCCAAATTCAACCTTTCCCTAAAGGGGTGAATATTATTGTTACTGAAGAAAATATTGAT
ATTGATCCCAATAATCTCCCAGATGATCCCGAAGAATTTGAGCAACTTATGACGGATTTCTTTGGACGTGTGGAAGATTT
AAAACAAAATGGCGGAACAATGGCAGATACAAGTACAACTGAAACAAAAGAAACAAAAGTAGAAAATAAACCAGATCCAG
ATTTTGTCTTCTATTCTCTAGAATTTGAAAACATGTCTCAACTTTTAACAGCAGTAAAAAATGTTAAAATTGATGCAGAG
GAATCTGAACTTTATAGCTATGAAGATAAGTTTTATTTGATTATTTTGGACAATCAAAAGTCAAAAGGAAAGACAGCCGT
AAGTTCGATGCGTGCCCGAATGTTAGAATACGGACAGGAAACGATCAACAGTCGCGAAACACTACAAGAATACGGCGAGA
TACTAATCAATACACGTGCTTTGGAAGTTCTCTCAAAAATTTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-224)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A139MDU9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Lactococcus lactis subsp. cremoris KW2

54.077

100

0.555
  mecA Lactococcus lactis subsp. lactis strain DGCC12653

54.077

100

0.555