Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   J0J36_RS02000 Genome accession   NZ_CP071293
Coordinates   417319..418002 (+) Length   227 a.a.
NCBI ID   WP_019292408.1    Uniprot ID   A0A139MDU9
Organism   Lactococcus sp. LG1074     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 412319..423002
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J0J36_RS01990 (J0J36_01990) rpoC 412424..416071 (+) 3648 WP_019292410.1 DNA-directed RNA polymerase subunit beta' -
  J0J36_RS01995 (J0J36_01995) - 416164..417072 (-) 909 WP_019292409.1 diacylglycerol kinase family protein -
  J0J36_RS02000 (J0J36_02000) mecA 417319..418002 (+) 684 WP_019292408.1 adaptor protein MecA Regulator
  J0J36_RS02005 (J0J36_02005) - 418006..419262 (+) 1257 WP_019292407.1 glycosyltransferase family 4 protein -
  J0J36_RS02010 (J0J36_02010) sufC 419340..420110 (+) 771 WP_019292406.1 Fe-S cluster assembly ATPase SufC -
  J0J36_RS02015 (J0J36_02015) sufD 420182..421438 (+) 1257 WP_019292405.1 Fe-S cluster assembly protein SufD -
  J0J36_RS02020 (J0J36_02020) - 421438..422649 (+) 1212 WP_019292404.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 26254.39 Da        Isoelectric Point: 4.0031

>NTDB_id=544667 J0J36_RS02000 WP_019292408.1 417319..418002(+) (mecA) [Lactococcus sp. LG1074]
MQYEEINEKTIKISLTFQDLVDHDVKLSDFFTNQSMVENLFYELVEELGLEERFSSGLLTFQIQPFPKGVNIIVTEENID
IDPNNLPDDPEEFEQLMTDFFGRVEDLKQNGGTMADTSTTETKETKVENKPDPDFVFYSLEFENMSQLLTAVKNVKIDAE
ESELYSYEDKFYLIILDNQKSKGKTAVSSMRARMLEYGQETINSRETLQEYGEILINTRALEVLSKI

Nucleotide


Download         Length: 684 bp        

>NTDB_id=544667 J0J36_RS02000 WP_019292408.1 417319..418002(+) (mecA) [Lactococcus sp. LG1074]
ATGCAATATGAAGAAATAAACGAAAAAACGATAAAGATTAGCCTAACCTTTCAAGATTTGGTTGATCATGATGTCAAACT
CTCTGATTTTTTTACGAACCAGTCAATGGTTGAAAATCTTTTTTATGAATTAGTAGAAGAACTAGGACTTGAGGAAAGGT
TCTCATCAGGACTTTTAACTTTCCAAATTCAACCTTTCCCTAAAGGGGTGAATATTATTGTTACTGAAGAAAATATTGAT
ATTGATCCCAATAATCTCCCTGATGATCCCGAAGAATTTGAGCAGCTTATGACGGATTTCTTTGGACGTGTGGAAGATTT
AAAACAAAATGGCGGAACAATGGCAGATACAAGTACAACTGAAACAAAAGAAACAAAAGTAGAAAATAAACCAGATCCAG
ATTTTGTCTTCTATTCTCTAGAATTTGAAAACATGTCTCAACTTTTGACAGCAGTAAAAAATGTTAAAATTGATGCAGAG
GAATCTGAACTTTATAGCTATGAAGATAAGTTTTATTTGATTATTTTGGACAATCAAAAGTCAAAAGGAAAGACAGCAGT
AAGTTCGATGCGTGCCCGAATGTTAGAATACGGACAGGAAACAATCAACAGTCGCGAAACACTACAAGAATACGGCGAGA
TACTAATCAATACACGTGCTTTGGAAGTTCTCTCAAAAATTTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-224)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A139MDU9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Lactococcus lactis subsp. cremoris KW2

54.077

100

0.555
  mecA Lactococcus lactis subsp. lactis strain DGCC12653

54.077

100

0.555