Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   J0J32_RS01975 Genome accession   NZ_CP071285
Coordinates   410088..410771 (+) Length   227 a.a.
NCBI ID   WP_004259224.1    Uniprot ID   A0A1I4FNQ8
Organism   Lactococcus garvieae strain LG728     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 405088..415771
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J0J32_RS01965 (J0J32_01965) rpoC 405195..408842 (+) 3648 WP_004259228.1 DNA-directed RNA polymerase subunit beta' -
  J0J32_RS01970 (J0J32_01970) - 408936..409844 (-) 909 WP_004259225.1 diacylglycerol kinase family protein -
  J0J32_RS01975 (J0J32_01975) mecA 410088..410771 (+) 684 WP_004259224.1 adaptor protein MecA Regulator
  J0J32_RS01980 (J0J32_01980) - 410775..412031 (+) 1257 WP_004259207.1 MraY family glycosyltransferase -
  J0J32_RS01985 (J0J32_01985) sufC 412109..412879 (+) 771 WP_004259205.1 Fe-S cluster assembly ATPase SufC -
  J0J32_RS01990 (J0J32_01990) sufD 412951..414207 (+) 1257 WP_019299087.1 Fe-S cluster assembly protein SufD -
  J0J32_RS01995 (J0J32_01995) - 414207..415418 (+) 1212 WP_004259200.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 26239.38 Da        Isoelectric Point: 4.0202

>NTDB_id=544578 J0J32_RS01975 WP_004259224.1 410088..410771(+) (mecA) [Lactococcus garvieae strain LG728]
MQYEEINEKTIKISLTFQDLVDHDVKLSDFFTNQSMVENLFYELVEELGLEERFSSGLLTFQIQPFPKGVNIIVTEENID
IDPNNLPDDPEEFEQLMTDFFGRVEDLKQNGGTMADTSTTETKETKVENKPDPDFVFYSLEFENMSQLLTAVKNVKIDAE
ESELYSYQDKFYLIILDNQKSKGKTAVSSMRARMLEYGQETVNSRETLQEYGEILINTRALEVLSKI

Nucleotide


Download         Length: 684 bp        

>NTDB_id=544578 J0J32_RS01975 WP_004259224.1 410088..410771(+) (mecA) [Lactococcus garvieae strain LG728]
ATGCAATACGAAGAAATAAACGAAAAAACGATAAAGATTAGCCTAACCTTTCAAGATTTGGTTGATCATGATGTCAAACT
CTCTGATTTTTTTACTAACCAGTCAATGGTTGAAAATCTTTTTTATGAATTAGTAGAAGAGCTAGGACTTGAGGAAAGAT
TCTCATCAGGACTTTTAACTTTCCAAATTCAACCTTTCCCTAAAGGGGTGAATATCATTGTTACCGAGGAAAACATTGAT
ATTGATCCCAATAATCTCCCGGATGATCCTGAAGAATTTGAGCAGCTGATGACGGATTTCTTTGGGCGTGTGGAAGATTT
AAAACAAAATGGCGGAACAATGGCAGATACAAGTACAACTGAAACGAAAGAAACAAAAGTAGAAAATAAACCAGACCCAG
ATTTTGTCTTCTATTCTCTAGAATTTGAAAATATGTCTCAACTTTTGACAGCAGTAAAAAATGTTAAAATTGATGCAGAA
GAGTCTGAACTTTACAGTTACCAAGATAAGTTTTATTTGATTATTTTGGACAATCAAAAATCAAAAGGAAAAACAGCCGT
CAGTTCGATGCGTGCCCGAATGTTAGAATACGGCCAGGAAACGGTCAACAGTCGTGAAACCCTACAAGAATACGGCGAGA
TACTAATCAATACGCGTGCTTTGGAAGTTCTCTCAAAAATTTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-224)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1I4FNQ8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Lactococcus lactis subsp. cremoris KW2

54.661

100

0.568
  mecA Lactococcus lactis subsp. lactis strain DGCC12653

54.077

100

0.555