Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   LO740_RS12865 Genome accession   NZ_CP087294
Coordinates   2608532..2610364 (-) Length   610 a.a.
NCBI ID   WP_001283427.1    Uniprot ID   -
Organism   Escherichia coli strain APEC E956     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2603532..2615364
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LO740_RS12815 (LO740_12795) azuC 2603542..2603628 (-) 87 WP_010723106.1 stress response protein AzuC -
  LO740_RS12820 (LO740_12800) yecR 2603891..2604214 (+) 324 WP_001237876.1 YecR-like lipofamily protein -
  LO740_RS12825 (LO740_12805) ftnA 2604386..2604883 (+) 498 WP_000917208.1 non-heme ferritin -
  LO740_RS12830 (LO740_12810) yecH 2604921..2605160 (-) 240 WP_000377224.1 YecH family metal-binding protein -
  LO740_RS12835 (LO740_12815) tyrP 2605351..2606562 (+) 1212 WP_000797555.1 tyrosine transporter TyrP -
  LO740_RS12840 (LO740_12820) yecA 2606612..2607277 (-) 666 WP_000847885.1 UPF0149 family protein YecA -
  LO740_RS12860 (LO740_12840) pgsA 2607927..2608475 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  LO740_RS12865 (LO740_12845) uvrC 2608532..2610364 (-) 1833 WP_001283427.1 excinuclease ABC subunit UvrC Machinery gene
  LO740_RS12870 (LO740_12850) letA 2610361..2611017 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  LO740_RS24530 - 2611159..2611275 (+) 117 WP_001302039.1 hypothetical protein -
  LO740_RS12875 (LO740_12855) yecU 2611313..2611489 (+) 177 WP_000590344.1 protein YecU -
  LO740_RS12880 (LO740_12860) yecF 2611476..2611700 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  LO740_RS12885 (LO740_12865) sdiA 2611767..2612489 (-) 723 WP_001154273.1 transcriptional regulator SdiA -
  LO740_RS12890 (LO740_12870) tcyN 2612719..2613471 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  LO740_RS12895 (LO740_12875) tcyL 2613468..2614136 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  LO740_RS12900 (LO740_12880) dcyD 2614151..2615137 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 68202.06 Da        Isoelectric Point: 9.3685

>NTDB_id=544551 LO740_RS12865 WP_001283427.1 2608532..2610364(-) (uvrC) [Escherichia coli strain APEC E956]
MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLL
EHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
NRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETASQNLEFEEAARIRDQIQAVRRVT
EKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLD
FNLSDKTLLADSLSELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEVKRMECFDI
SHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRYGKAIDESKIPDVILIDGGKGQLAQAKNVFA
ELDVSWDKNHPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLET
IEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=544551 LO740_RS12865 WP_001283427.1 2608532..2610364(-) (uvrC) [Escherichia coli strain APEC E956]
GTGAGTGATCAGTTTGACGCAAAAGCGTTTTTAAAAACCGTAACCAGCCAGCCAGGCGTTTATCGCATGTACGATGCTGG
TGGTACGGTTATCTATGTCGGCAAAGCGAAAGACCTGAAAAAACGGCTTTCCAGCTATTTCCGTAGCAACCTCGCTTCGC
GCAAAACCGAAGCGCTGGTCGCCCAGATCCAGCAAATTGATGTAACGGTTACTCATACAGAAACCGAAGCGCTGTTGCTG
GAACACAACTACATCAAACTCTATCAGCCGCGTTACAACGTTTTGCTACGCGATGATAAATCTTATCCCTTTATCTTCCT
GAGTGGCGATACCCATCCGCGTCTGGCGATGCATCGTGGTGCGAAGCATGCTAAAGGTGAATATTTCGGCCCGTTCCCGA
ATGGCTATGCCGTACGTGAAACACTGGCGCTACTGCAAAAGATATTCCCCATTCGCCAGTGCGAAAATAGTGTTTATCGC
AATCGCTCGCGTCCGTGTCTGCAATATCAGATAGGGCGCTGTCTGGGACCGTGCGTTGAAGGACTGGTGAGTGAAGAAGA
ATACGCTCAGCAGGTCGAGTATGTGCGCCTGTTTTTGTCTGGCAAAGATGATCAGGTGCTTACGCAACTCATTAGTCGTA
TGGAAACTGCCAGCCAGAATCTGGAGTTTGAAGAAGCGGCACGTATTCGCGACCAAATTCAGGCGGTGCGACGCGTCACC
GAAAAACAGTTTGTGTCCAATACCGGCGACGACCTCGACGTTATTGGTGTGGCGTTCGATGCGGGCATGGCTTGTGTCCA
CGTATTGTTCATTCGTCAGGGTAAAGTGCTCGGCAGCCGCAGCTATTTCCCGAAAGTGCCTGGCGGTACGGAACTGAGCG
AGGTGGTGGAAACCTTCGTAGGTCAGTTCTATTTACAAGGCAGCCAGATGCGCACCTTACCGGGTGAGATCCTGCTCGAT
TTTAATCTTAGCGATAAAACGCTGCTCGCCGATTCCCTTTCAGAACTGGCGGGACGCAAGATTAATGTTCAAACCAAACC
TCGCGGCGATCGGGCGCGTTATCTGAAACTCGCGCGCACCAATGCGGCGACGGCATTAACCAGCAAACTTTCGCAGCAAT
CTACCGTTCACCAGCGACTGACCGCGCTTGCCAGCGTGTTGAAATTGCCGGAAGTGAAGCGGATGGAATGCTTTGACATC
AGCCATACCATGGGGGAACAAACCGTCGCTTCCTGTGTGGTGTTTGATGCTAACGGCCCGCTGCGTGCGGAGTATCGACG
CTATAACATTACTGGCATCACGCCGGGCGATGATTATGCGGCGATGAATCAGGTGCTGCGTCGGCGTTATGGTAAAGCCA
TCGACGAGAGTAAGATCCCGGATGTGATCCTTATCGACGGCGGCAAAGGCCAACTTGCGCAGGCGAAAAATGTTTTCGCC
GAACTGGATGTCTCATGGGATAAAAATCATCCGCTGCTACTAGGCGTTGCCAAAGGAGCAGATCGTAAGGCTGGGCTGGA
AACGCTGTTCTTTGAGCCGGAAGGTGAGGGATTCAGTTTGCCGCCAGATTCTCCCGCACTGCATGTTATCCAGCATATTC
GCGATGAATCACACGATCACGCGATTGGCGGGCACCGTAAAAAACGGGCGAAGGTCAAAAATACCAGTTCCCTGGAAACC
ATTGAAGGCGTCGGGCCAAAACGTCGGCAAATGTTGTTGAAATATATGGGCGGTTTGCAAGGTTTACGTAACGCCAGCGT
CGAGGAAATTGCAAAAGTGCCGGGTATTTCGCAAGGTCTGGCAGAAAAGATCTTCTGGTCGTTGAAACATTGA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(205-237)

Helix-hairpin-helix domain (HHH_5)

(558-609)

GIY-YIG catalytic domain (GIY-YIG)

(18-93)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-542)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

38.056

99.508

0.379
  uvrC Streptococcus pneumoniae R6

37.727

99.508

0.375
  uvrC Streptococcus pneumoniae D39

37.727

99.508

0.375