Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   LMF34_RS19590 Genome accession   NZ_CP086678
Coordinates   4108446..4109102 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain EFF60     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4103446..4114102
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LMF34_RS19560 dcyD 4104326..4105312 (+) 987 WP_020232905.1 D-cysteine desulfhydrase -
  LMF34_RS19565 tcyL 4105327..4105995 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  LMF34_RS19570 tcyN 4105992..4106744 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  LMF34_RS19575 sdiA 4106974..4107696 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  LMF34_RS19580 yecF 4107763..4107987 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  LMF34_RS19585 yecU 4107974..4108150 (-) 177 WP_000590347.1 protein YecU -
  LMF34_RS19590 letA 4108446..4109102 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  LMF34_RS19595 uvrC 4109099..4110931 (+) 1833 WP_201514467.1 excinuclease ABC subunit UvrC Machinery gene
  LMF34_RS19600 pgsA 4110988..4111536 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  LMF34_RS19620 yecA 4112187..4112852 (+) 666 WP_000847881.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=544064 LMF34_RS19590 WP_000611328.1 4108446..4109102(+) (letA) [Escherichia coli strain EFF60]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=544064 LMF34_RS19590 WP_000611328.1 4108446..4109102(+) (letA) [Escherichia coli strain EFF60]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTACAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482