Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   LN354_RS10985 Genome accession   NZ_CP086624
Coordinates   2268871..2269527 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain RIVM_C037791     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2263871..2274527
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LN354_RS10955 (LN354_10960) dcyD 2264751..2265737 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  LN354_RS10960 (LN354_10965) tcyL 2265752..2266420 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  LN354_RS10965 (LN354_10970) tcyN 2266417..2267169 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  LN354_RS10970 (LN354_10975) sdiA 2267399..2268121 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  LN354_RS10975 (LN354_10980) yecF 2268188..2268412 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  LN354_RS10980 (LN354_10985) yecU 2268399..2268575 (-) 177 WP_000590347.1 protein YecU -
  LN354_RS10985 (LN354_10990) letA 2268871..2269527 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  LN354_RS10990 (LN354_10995) uvrC 2269524..2271356 (+) 1833 WP_001551272.1 excinuclease ABC subunit UvrC Machinery gene
  LN354_RS10995 (LN354_11000) pgsA 2271413..2271961 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  LN354_RS11015 (LN354_11020) yecA 2272611..2273276 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=543569 LN354_RS10985 WP_000611328.1 2268871..2269527(+) (letA) [Escherichia coli strain RIVM_C037791]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=543569 LN354_RS10985 WP_000611328.1 2268871..2269527(+) (letA) [Escherichia coli strain RIVM_C037791]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGAGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482