Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   LN351_RS11210 Genome accession   NZ_CP086620
Coordinates   2303634..2304290 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain RIVM_C039205     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2298634..2309290
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LN351_RS11180 (LN351_11185) dcyD 2299514..2300500 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  LN351_RS11185 (LN351_11190) tcyL 2300515..2301183 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  LN351_RS11190 (LN351_11195) tcyN 2301180..2301932 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  LN351_RS11195 (LN351_11200) sdiA 2302162..2302884 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  LN351_RS11200 (LN351_11205) yecF 2302951..2303175 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  LN351_RS11205 (LN351_11210) yecU 2303162..2303338 (-) 177 WP_000590347.1 protein YecU -
  LN351_RS11210 (LN351_11215) letA 2303634..2304290 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  LN351_RS11215 (LN351_11220) uvrC 2304287..2306119 (+) 1833 WP_001551272.1 excinuclease ABC subunit UvrC Machinery gene
  LN351_RS11220 (LN351_11225) pgsA 2306176..2306724 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  LN351_RS11240 (LN351_11245) yecA 2307374..2308039 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=543317 LN351_RS11210 WP_000611328.1 2303634..2304290(+) (letA) [Escherichia coli strain RIVM_C039205]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=543317 LN351_RS11210 WP_000611328.1 2303634..2304290(+) (letA) [Escherichia coli strain RIVM_C039205]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGAGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482