Detailed information NTG0543197

Bioinformatically predicted

Overview

• Name: vicK
• Type: Regulator
• Locus tag: JZI48_RS08270
• Genome accession: NZ_CP071145
• Coordinates: 1693042..1694394 (+)
• Length: 450 a.a.
• NCBI ID: WP_012679848.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. equi strain 470_007
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	1695289..1696631	1693042..1694394	flank	895

Gene organization within MGE regions

Location: 1693042..1696631

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JZI48_RS08270 (JZI48_08270)	vicK	1693042..1694394 (+)	1353	WP_012679848.1	cell wall metabolism sensor histidine kinase VicK	Regulator
JZI48_RS08275 (JZI48_08275)	vicX	1694398..1695207 (+)	810	WP_042357090.1	MBL fold metallo-hydrolase	Regulator
JZI48_RS08280 (JZI48_08280)	-	1695289..1696631 (+)	1343	WP_173476811.1	IS3 family transposase	-

Sequence

Protein

• Length: 450 a.a.
• Molecular weight: 51530.96 Da
• Isoelectric Point: 5.5741

>NTDB_id=543197 JZI48_RS08270 WP_012679848.1 1693042..1694394(+) (vicK) [Streptococcus equi subsp. equi strain 470_007]
MTKDIIGNLSAFELAILLLLVFVAFYFIHLAIRDYRNARIIRLMSHKIRDLINGRYTDTINEKADIELMELSEQLNDLSD
VFRLTHENLAQEKNRLASILAYMTDGVLATNRSGKIIMINETAQKQLNLNREQALEKNITDLLDSDSPYTYRELVSKTPI
VTLNRRNDTGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNHVTQLSVEMTNFTAFMTSILNRFDLVKNQHTSTGKSYEIVRDYPITS
IWLEIDNDKMTQVIENILNNAIKYSPDGGKIIVNMKTTDTQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGAG
LGLAIAKEIIKQRRGFIWAKSDYGKGSTFTIVLPYEKDAAIYDEWEDDID

Nucleotide

• Length: 1353 bp

>NTDB_id=543197 JZI48_RS08270 WP_012679848.1 1693042..1694394(+) (vicK) [Streptococcus equi subsp. equi strain 470_007]
ATGACTAAGGACATCATTGGAAACCTTTCTGCATTTGAGCTAGCCATACTCTTATTGCTTGTTTTTGTTGCTTTTTATTT
CATTCATTTAGCCATTCGTGATTATCGCAATGCTCGGATCATTCGTCTGATGAGCCATAAGATAAGAGATTTGATCAATG
GTCGCTATACTGATACGATCAATGAAAAGGCTGATATTGAATTGATGGAGCTGTCTGAGCAGCTCAACGACCTATCAGAT
GTTTTTCGTCTGACCCATGAAAACCTTGCCCAAGAGAAAAATCGTCTTGCTAGTATTTTGGCTTATATGACAGATGGGGT
CCTTGCGACCAATCGTTCCGGCAAGATTATCATGATTAATGAGACTGCTCAAAAGCAGCTCAATTTAAATCGTGAGCAGG
CGCTGGAAAAAAACATTACAGATTTATTAGACAGTGACTCACCTTACACCTACCGAGAGCTGGTCTCAAAAACACCGATT
GTGACCTTAAATCGTCGTAATGACACAGGAGAGTTTGTTTCGCTGCGGCTGCGTTTTGCGCTTAATAGGCGAGAGAGCGG
CTTTATTTCAGGTCTAGTTGTTGTGCTTCATGACACGACTGAGCAGGAAAAGGAGGAGCGTGAGCGCAGACTCTTTGTCT
CAAATGTTAGCCATGAGCTTCGCACACCTTTGACCTCTGTCAAGTCATACCTAGAGGCTCTAGATGAGGGCGCGCTAAAG
GAGGACATAGCCCCAAGCTTTATAAAGGTCTCACTAGACGAAACCAATCGCATGATGCGCATGATTTCAGATTTGCTCAA
TCTATCAAGAATTGATAATCATGTGACACAGCTGTCTGTTGAAATGACCAACTTTACAGCCTTTATGACCTCTATCTTAA
ACCGCTTTGATTTGGTGAAAAATCAGCACACCAGTACAGGAAAATCCTATGAAATTGTCAGAGATTACCCTATCACCTCT
ATTTGGCTAGAAATTGATAACGATAAAATGACGCAGGTCATTGAAAATATTTTAAACAATGCCATCAAATATTCACCTGA
TGGTGGGAAAATTATCGTAAACATGAAAACAACAGATACCCAGCTAATCATTTCGATTTCTGATGAGGGATTGGGCATAC
CAAAGAAGGACCTGCCTTTGATTTTTGACCGTTTTTACCGAGTGGATAAGGCTAGAAGTCGGGCGCAGGGGGGGGCCGGC
TTAGGGCTGGCTATTGCTAAAGAAATTATTAAGCAGCGCCGCGGCTTTATCTGGGCTAAGAGTGACTATGGCAAGGGGTC
AACCTTTACCATTGTGTTACCTTACGAAAAGGATGCTGCTATCTATGATGAATGGGAGGATGATATTGATTAA

Domains

Predicted by InterproScan.

• PAS fold (PAS) (95-197)

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (326-436)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicK	Streptococcus mutans UA159	73.188	92	0.673
micB	Streptococcus pneumoniae Cp1015	66.353	94.444	0.627