Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   LN353_RS10810 Genome accession   NZ_CP086616
Coordinates   2247218..2247874 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain RIVM_C039629     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2242218..2252874
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LN353_RS10780 (LN353_10785) dcyD 2243098..2244084 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  LN353_RS10785 (LN353_10790) tcyL 2244099..2244767 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  LN353_RS10790 (LN353_10795) tcyN 2244764..2245516 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  LN353_RS10795 (LN353_10800) sdiA 2245746..2246468 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  LN353_RS10800 (LN353_10805) yecF 2246535..2246759 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  LN353_RS10805 (LN353_10810) yecU 2246746..2246922 (-) 177 WP_000590347.1 protein YecU -
  LN353_RS10810 (LN353_10815) letA 2247218..2247874 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  LN353_RS10815 (LN353_10820) uvrC 2247871..2249703 (+) 1833 WP_001551272.1 excinuclease ABC subunit UvrC Machinery gene
  LN353_RS10820 (LN353_10825) pgsA 2249760..2250308 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  LN353_RS10840 (LN353_10845) yecA 2250958..2251623 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=543149 LN353_RS10810 WP_000611328.1 2247218..2247874(+) (letA) [Escherichia coli strain RIVM_C039629]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=543149 LN353_RS10810 WP_000611328.1 2247218..2247874(+) (letA) [Escherichia coli strain RIVM_C039629]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGAGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482