Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   JZI57_RS05975 Genome accession   NZ_CP071142
Coordinates   1195192..1195941 (+) Length   249 a.a.
NCBI ID   WP_012679946.1    Uniprot ID   C0M6E8
Organism   Streptococcus equi subsp. equi strain 489_004     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1190192..1200941
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JZI57_RS05950 (JZI57_05950) recX 1190595..1191371 (-) 777 WP_012679951.1 recombination regulator RecX -
  JZI57_RS05955 (JZI57_05955) - 1191435..1192403 (+) 969 WP_012679950.1 DNA-binding protein -
  JZI57_RS05960 (JZI57_05960) rlmD 1192400..1193767 (+) 1368 WP_012679949.1 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD -
  JZI57_RS05965 (JZI57_05965) - 1194088..1194345 (+) 258 WP_012679948.1 Blp family class II bacteriocin -
  JZI57_RS05970 (JZI57_05970) - 1194362..1194565 (+) 204 WP_012679947.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  JZI57_RS05975 (JZI57_05975) comE/blpR 1195192..1195941 (+) 750 WP_012679946.1 response regulator transcription factor Regulator
  JZI57_RS05980 (JZI57_05980) - 1196355..1197275 (+) 921 WP_231296174.1 GHKL domain-containing protein -
  JZI57_RS05985 (JZI57_05985) - 1197397..1197528 (-) 132 WP_012677513.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  JZI57_RS05990 (JZI57_05990) - 1197628..1198986 (-) 1359 WP_012679944.1 bacteriocin secretion accessory protein -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29257.72 Da        Isoelectric Point: 8.7559

>NTDB_id=543061 JZI57_RS05975 WP_012679946.1 1195192..1195941(+) (comE/blpR) [Streptococcus equi subsp. equi strain 489_004]
MRVVILEDDMIQQRYLEKLIKELEVKHQLLFQGLDCFGRPHQLLSAIKKNCGQQLFFLDIEIKNENKKGLEVARQIRQIN
PDAMIVFVTTHSEFMPLAFQYQVSALDYIDKELPQTEFVQRVETALLYAVRQNSETIAESAFYFTSRYAQVQVPFNDILY
IETSSRAHRVNLYTKKERMQFTGTLTDILKQESRFLQCHRSFLINHRNVVRVDKIERVVYFRNGSSCLIARSKMNSVLTT
IENLHRGDN

Nucleotide


Download         Length: 750 bp        

>NTDB_id=543061 JZI57_RS05975 WP_012679946.1 1195192..1195941(+) (comE/blpR) [Streptococcus equi subsp. equi strain 489_004]
GTGAGAGTAGTTATTTTAGAAGATGATATGATTCAGCAGAGATATTTAGAAAAGCTCATTAAAGAGCTTGAGGTTAAGCA
CCAGCTATTATTTCAAGGACTTGACTGTTTTGGAAGGCCTCATCAGCTATTAAGTGCTATCAAGAAGAACTGTGGTCAGC
AGCTATTCTTTTTAGATATTGAGATAAAAAATGAGAACAAAAAAGGGCTTGAGGTTGCTAGGCAAATTCGTCAGATAAAT
CCAGATGCGATGATTGTTTTTGTAACGACTCACTCGGAATTTATGCCCTTGGCTTTTCAGTATCAGGTATCTGCTTTGGA
CTATATCGATAAAGAGCTGCCTCAAACTGAGTTTGTTCAACGGGTAGAGACTGCTTTATTATATGCTGTGCGGCAAAATA
GTGAAACGATAGCGGAAAGTGCTTTTTATTTTACATCTCGTTATGCTCAGGTACAGGTGCCTTTTAATGATATCCTGTAT
ATTGAGACATCGTCACGAGCGCATCGTGTCAATTTGTATACAAAAAAGGAGAGAATGCAATTTACGGGGACTTTGACGGA
TATTTTGAAGCAAGAGTCTCGTTTTTTGCAATGTCATCGTTCTTTTTTGATTAATCATAGGAATGTCGTTAGGGTAGATA
AGATTGAGCGAGTGGTTTATTTTCGAAATGGCTCTAGCTGCTTAATTGCTCGTAGTAAAATGAACAGTGTTTTAACAACA
ATTGAGAACCTACATAGAGGAGATAATTAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C0M6E8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

52.209

100

0.522
  comE/comE1 Streptococcus equinus JB1

40.167

95.984

0.386