Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   JWR96_RS03345 Genome accession   NZ_CP070856
Coordinates   645661..647133 (+) Length   490 a.a.
NCBI ID   WP_043735252.1    Uniprot ID   A0AAX4A423
Organism   Lactococcus cremoris strain GR0507     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 640661..652133
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JWR96_RS03315 (JWR96_03315) - 641129..641965 (+) 837 WP_043735256.1 metallophosphoesterase -
  JWR96_RS03320 (JWR96_03320) - 642058..642969 (+) 912 WP_043735255.1 CHAP domain-containing protein -
  JWR96_RS03325 (JWR96_03325) - 643205..643567 (+) 363 WP_043735253.1 TIGR02328 family protein -
  JWR96_RS03330 (JWR96_03330) - 643891..644136 (+) 246 WP_011676633.1 type B 50S ribosomal protein L31 -
  JWR96_RS03335 (JWR96_03335) - 644269..644799 (+) 531 WP_011834860.1 DUF177 domain-containing protein -
  JWR96_RS03340 (JWR96_03340) covR 644956..645648 (+) 693 WP_011676631.1 response regulator transcription factor Regulator
  JWR96_RS03345 (JWR96_03345) covS 645661..647133 (+) 1473 WP_043735252.1 HAMP domain-containing histidine kinase Regulator
  JWR96_RS03350 (JWR96_03350) - 647319..648560 (+) 1242 WP_043735251.1 ammonium transporter -
  JWR96_RS03355 (JWR96_03355) - 648643..648984 (+) 342 WP_011676628.1 P-II family nitrogen regulator -
  JWR96_RS03360 (JWR96_03360) murD 649152..650501 (+) 1350 WP_043735249.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  JWR96_RS03365 (JWR96_03365) murG 650744..651817 (+) 1074 WP_021037555.1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase -

Sequence

Protein


Download         Length: 490 a.a.        Molecular weight: 55917.77 Da        Isoelectric Point: 4.7011

>NTDB_id=541066 JWR96_RS03345 WP_043735252.1 645661..647133(+) (covS) [Lactococcus cremoris strain GR0507]
MKKLFTFNKKKETVEESSAKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSFIKEEQRLLTGSMDSVEEVLEQADAPL
NSTNLNTYIEATSKIQNGESEGMSLGSIIGTRKAFYIYDLNHKLLYSTNRHDFGFQKQGNNEMKEIQGENPGYLVQRKIV
SKGTGQVVGYLQAFYDTTTYHRISNLLLVVLLILEIVALIVAQMIGYFMANYFMKPLEKLYQGMQEMANDPTNDFKPIEI
ESGDEIEELAHVYNNMMLKMKAYLEQQDRFVSDVSHELRTPLAVLDGHINLLNRWGKNDPEVLDESLQASLDEVDRMKKM
LEEMLALARLENVDLSSEELDCDVGKVSNHALKNFQLLHEDFEIVLDNQLIYPVHARISENHFEQGLRILLDNAVKYSPD
DRKEIVITVSEDEQFVITSVSDKGIGIAEEDINHLFERFFRADKARNREIGGTGLGLPILARLAENYQGEIEVSSELGIG
STFTLKFPKM

Nucleotide


Download         Length: 1473 bp        

>NTDB_id=541066 JWR96_RS03345 WP_043735252.1 645661..647133(+) (covS) [Lactococcus cremoris strain GR0507]
ATGAAAAAATTATTCACTTTCAACAAGAAAAAGGAAACGGTAGAAGAAAGTTCGGCTAAGCGGTCTATTATGCTTAGGTG
GGCTTTTGCTAACACCGTTTTTTGTTTTATTACTTTTACTCTTTTTGCAACATTAACTTATCAACTGACCATAAGTTCTT
TCATTAAGGAGGAACAAAGGTTATTGACAGGTTCAATGGACAGCGTTGAAGAGGTATTAGAACAAGCGGATGCTCCTTTA
AATTCAACTAATTTGAATACTTATATTGAAGCGACATCAAAGATTCAAAATGGGGAATCGGAAGGAATGAGTCTGGGAAG
TATCATCGGGACTCGGAAAGCATTTTATATTTATGATTTAAATCATAAGTTATTATATTCAACTAATCGACATGATTTTG
GATTTCAAAAGCAAGGCAATAATGAAATGAAAGAAATTCAAGGTGAGAATCCAGGTTATTTAGTCCAAAGGAAGATTGTT
TCTAAAGGGACGGGACAGGTTGTAGGCTATTTACAGGCATTTTATGACACGACAACTTATCATCGGATTTCCAATCTCCT
TTTAGTCGTCTTGTTAATTTTAGAAATTGTCGCTTTAATCGTTGCGCAAATGATTGGTTATTTTATGGCGAATTATTTTA
TGAAGCCTTTAGAAAAACTTTATCAGGGAATGCAGGAAATGGCGAATGACCCCACGAATGATTTCAAACCTATCGAAATT
GAAAGTGGTGATGAAATTGAAGAATTAGCTCATGTTTATAATAATATGATGCTGAAAATGAAAGCATATCTTGAACAGCA
AGATCGGTTTGTCTCTGACGTTTCACATGAATTAAGGACTCCGCTAGCAGTTTTGGACGGTCATATTAATCTCTTAAATC
GTTGGGGGAAAAATGATCCAGAGGTTTTGGATGAATCTTTGCAGGCGAGTTTGGATGAAGTAGACCGAATGAAGAAAATG
CTTGAAGAAATGCTTGCTTTGGCTAGGCTTGAAAATGTAGATTTGTCCAGTGAAGAATTGGATTGTGACGTTGGGAAAGT
ATCTAATCATGCGCTTAAAAACTTCCAACTTCTACATGAGGATTTTGAGATTGTACTCGATAATCAGCTTATCTACCCTG
TCCATGCCCGGATATCTGAAAATCATTTTGAACAAGGATTACGCATTTTGTTAGATAATGCTGTTAAGTATTCTCCGGAT
GATCGAAAGGAGATTGTGATTACTGTTTCAGAAGATGAACAGTTTGTCATTACTAGTGTTTCTGATAAAGGAATCGGAAT
TGCCGAAGAAGATATTAATCATCTTTTTGAGCGATTCTTTCGAGCGGATAAGGCACGTAACCGTGAGATTGGCGGAACTG
GTTTAGGTTTACCAATTCTTGCTCGTTTAGCCGAAAATTATCAAGGGGAGATTGAAGTTAGTTCTGAGCTTGGGATTGGT
TCAACTTTTACCTTAAAATTTCCAAAAATGTGA

Domains

Predicted by InterproScan.

HAMP domain (HAMP)

(208-258)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(380-488)

ArlS sensor domain (ArlS_N)

(54-185)

His Kinase A (phospho-acceptor) domain (HisKA)

(267-332)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

94.49

100

0.945