Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   LL148_RS06140 Genome accession   NZ_CP086161
Coordinates   1194714..1195379 (-) Length   221 a.a.
NCBI ID   WP_002853205.1    Uniprot ID   Q0P933
Organism   Campylobacter jejuni strain SHI4648     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1189714..1200379
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LL148_RS06125 (LL148_06125) groES 1191575..1191835 (+) 261 WP_002784368.1 co-chaperone GroES -
  LL148_RS06130 (LL148_06130) groL 1191856..1193493 (+) 1638 WP_002853460.1 chaperonin GroEL -
  LL148_RS06135 (LL148_06135) dccS 1193513..1194721 (-) 1209 WP_180819934.1 two-component system sensor histidine kinase DccS -
  LL148_RS06140 (LL148_06140) ciaR 1194714..1195379 (-) 666 WP_002853205.1 two-component system response regulator DccR Regulator
  LL148_RS06145 (LL148_06145) - 1195527..1196126 (+) 600 WP_002866222.1 bacteriohemerythrin -
  LL148_RS06150 (LL148_06150) - 1196137..1196376 (+) 240 Protein_1195 ribbon-helix-helix domain-containing protein -
  LL148_RS06160 (LL148_06160) - 1196765..1198012 (-) 1248 WP_002853920.1 ArsS family sensor histidine kinase -
  LL148_RS06165 (LL148_06165) - 1198009..1198683 (-) 675 WP_002853566.1 response regulator transcription factor -
  LL148_RS06170 (LL148_06170) htrA 1198759..1200177 (-) 1419 WP_002853541.1 serine protease HtrA -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25633.32 Da        Isoelectric Point: 4.6834

>NTDB_id=540825 LL148_RS06140 WP_002853205.1 1194714..1195379(-) (ciaR) [Campylobacter jejuni strain SHI4648]
MAAKILLLEDDLSLSEIIEEFLNDEGYEVFLCDNAQEALDMAYERYFDLWILDVKVPLGDGFSLLKELRKSGKQTPAIFM
TSLNTTNDLKQGFDAGCDDYIKKPFELAELSIRVKALLKRAFSHKNEDFEDLGDGFRFEFTTQILYHNNKALTLPSKEIK
LLSLLLKNKNNFLSTERIFEELWDYDEEPSELSLRAYVKNLRKILGKEKIINQRGRGYCYG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=540825 LL148_RS06140 WP_002853205.1 1194714..1195379(-) (ciaR) [Campylobacter jejuni strain SHI4648]
ATGGCTGCTAAAATTTTACTTTTAGAAGATGATTTGAGCTTGAGTGAGATCATTGAAGAGTTTTTAAACGATGAAGGATA
TGAAGTATTTTTATGTGATAATGCACAAGAAGCTTTAGATATGGCTTATGAAAGATATTTTGATCTTTGGATTTTAGATG
TAAAAGTTCCTTTAGGAGATGGATTTTCATTACTTAAAGAATTAAGAAAAAGCGGAAAGCAAACTCCAGCAATTTTCATG
ACTTCTTTAAACACAACAAACGATTTAAAACAAGGCTTTGACGCAGGTTGTGATGATTATATAAAAAAACCTTTTGAACT
TGCCGAGTTATCTATCAGGGTTAAAGCTTTGCTTAAAAGAGCTTTTTCACATAAAAATGAAGATTTTGAAGATTTAGGAG
ATGGATTTAGATTTGAATTTACTACACAAATTCTTTACCATAATAATAAAGCCTTGACTTTACCGAGTAAAGAAATTAAG
CTTTTGTCTTTATTACTTAAAAATAAAAACAACTTTTTAAGCACAGAGAGAATTTTTGAAGAACTCTGGGATTATGATGA
GGAGCCTAGTGAGCTAAGTTTAAGAGCTTATGTAAAAAATTTACGTAAAATTTTAGGAAAAGAAAAAATTATAAATCAAA
GAGGCAGGGGATATTGCTATGGCTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(150-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q0P933

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

36.364

99.548

0.362
  ciaR Streptococcus pneumoniae D39

36.364

99.548

0.362
  ciaR Streptococcus pneumoniae R6

36.364

99.548

0.362
  ciaR Streptococcus pneumoniae TIGR4

36.364

99.548

0.362