Detailed information    

insolico Bioinformatically predicted

Overview

Name   degS   Type   Regulator
Locus tag   JWY35_RS18910 Genome accession   NZ_CP070485
Coordinates   3521338..3522495 (-) Length   385 a.a.
NCBI ID   WP_003227983.1    Uniprot ID   A0A199WDV9
Organism   Bacillus subtilis strain JNFE1126     
Function   phosphorylation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 3516338..3527495
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JWY35_RS18880 (JWY35_18735) yvyF 3516591..3517010 (-) 420 WP_014481050.1 TIGR03826 family flagellar region protein -
  JWY35_RS18885 (JWY35_18740) comFC 3517083..3517805 (-) 723 WP_014481051.1 comF operon protein ComFC Machinery gene
  JWY35_RS18890 (JWY35_18745) comFB 3517769..3518065 (-) 297 WP_003227989.1 late competence protein ComFB -
  JWY35_RS18895 (JWY35_18750) comFA 3518125..3519516 (-) 1392 WP_014481052.1 ATP-dependent helicase ComFA Machinery gene
  JWY35_RS18900 (JWY35_18755) fakBA 3519623..3520468 (-) 846 WP_014481053.1 DegV family protein -
  JWY35_RS18905 (JWY35_18760) degU 3520566..3521255 (-) 690 WP_014481054.1 two-component system response regulator DegU Regulator
  JWY35_RS18910 (JWY35_18765) degS 3521338..3522495 (-) 1158 WP_003227983.1 two-component sensor histidine kinase DegS Regulator
  JWY35_RS18915 (JWY35_18770) - 3522712..3523365 (+) 654 WP_014481055.1 YigZ family protein -
  JWY35_RS18920 (JWY35_18775) - 3523365..3524357 (+) 993 WP_014481056.1 LCP family protein -
  JWY35_RS18925 (JWY35_18780) - 3524955..3525419 (+) 465 WP_225910700.1 hypothetical protein -
  JWY35_RS18930 (JWY35_18785) - 3525468..3525923 (+) 456 WP_014481057.1 hypothetical protein -
  JWY35_RS18935 (JWY35_18790) - 3525974..3526426 (+) 453 WP_014481058.1 hypothetical protein -
  JWY35_RS18940 (JWY35_18795) - 3526502..3527281 (+) 780 WP_014481059.1 hypothetical protein -

Sequence

Protein


Download         Length: 385 a.a.        Molecular weight: 44957.76 Da        Isoelectric Point: 6.2957

>NTDB_id=540123 JWY35_RS18910 WP_003227983.1 3521338..3522495(-) (degS) [Bacillus subtilis strain JNFE1126]
MNKTKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVQTRHARNRLSEVSR
NFHRFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLREVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGAEDGFQEIKNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGETEDQRLAPQFEVALFRLAQEAVSNALKHSESEEITVKVEI
TKDFVILMIKDNGKGFDLKEAKEKKNKSFGLLGMKERVDLLEGTMTIDSKIGLGTFIMIKVPLSL

Nucleotide


Download         Length: 1158 bp        

>NTDB_id=540123 JWY35_RS18910 WP_003227983.1 3521338..3522495(-) (degS) [Bacillus subtilis strain JNFE1126]
ATGAATAAAACAAAGATGGATTCCAAAGTGCTGGATTCTATTTTGATGAAGATGCTGAAAACCGTTGACGGGAGCAAGGA
CGAAGTTTTTCAAATCGGGGAGCAGTCACGCCAGCAGTATGAACAGCTGGTCGAAGAACTGAAACAAATTAAACAGCAGG
TGTATGAAGTGATCGAGCTTGGCGATAAACTTGAAGTGCAAACCCGCCATGCGAGAAACCGTTTATCCGAGGTCAGCCGT
AATTTTCATAGATTCAGTGAAGAGGAAATCCGCAATGCTTATGAAAAAGCCCATAAGCTGCAGGTAGAATTGACGATGAT
CCAGCAGCGTGAGAAGCAATTGCGCGAACGGCGGGACGATTTGGAGCGCAGATTGCTAGGGCTTCAGGAAATCATTGAGC
GGTCAGAATCATTAGTAAGCCAAATTACAGTTGTGCTCAACTACTTGAATCAGGATTTGCGCGAAGTTGGACTGCTTCTT
GCTGATGCTCAGGCAAAACAGGATTTCGGCTTAAGGATTATTGAGGCGCAGGAAGAAGAGCGAAAAAGAGTCTCAAGAGA
AATCCATGACGGACCCGCTCAAATGCTGGCGAATGTTATGATGAGATCGGAATTAATCGAGCGGATTTTCCGTGACCGGG
GCGCAGAGGACGGATTCCAAGAAATTAAAAATCTACGCCAAAATGTTCGGAATGCCCTTTACGAAGTGAGAAGGATTATA
TATGATTTAAGACCGATGGCCCTTGATGACCTAGGCCTGATTCCAACTTTAAGAAAATATCTATATACAACCGAGGAATA
TAACGGGAAGGTCAAAATACATTTTCAGTGCATTGGAGAAACAGAGGATCAGAGGCTAGCGCCTCAGTTTGAGGTTGCGC
TCTTCAGGCTCGCACAGGAAGCTGTGTCTAATGCGCTAAAGCATTCTGAATCTGAAGAAATTACAGTCAAAGTTGAGATC
ACAAAGGATTTTGTGATTTTAATGATAAAAGATAACGGTAAAGGGTTCGACCTGAAGGAAGCGAAAGAGAAGAAAAACAA
ATCATTCGGCTTGCTGGGCATGAAAGAAAGAGTAGATTTATTGGAAGGAACGATGACAATAGATTCGAAAATAGGTCTTG
GGACATTTATTATGATTAAGGTTCCGTTATCTCTTTGA

Domains

Predicted by InterproScan.

Histidine kinase (HisKA_3)

(180-248)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(291-384)

Sensor protein DegS (DegS)

(12-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A199WDV9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  degS Bacillus subtilis subsp. subtilis str. 168

100

100

1