Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   JRY11_RS06745 Genome accession   NZ_CP070382
Coordinates   1251346..1252047 (+) Length   233 a.a.
NCBI ID   WP_004255173.1    Uniprot ID   S6FFV7
Organism   Lactococcus lactis strain KF140     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1246346..1257047
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JRY11_RS06730 (JRY11_001352) - 1248741..1249649 (+) 909 WP_023188514.1 diacylglycerol kinase family protein -
  JRY11_RS06735 (JRY11_001353) - 1249796..1250482 (+) 687 WP_004255158.1 amino acid ABC transporter permease -
  JRY11_RS06740 (JRY11_001354) - 1250482..1251216 (+) 735 WP_023188515.1 amino acid ABC transporter ATP-binding protein -
  JRY11_RS06745 (JRY11_001355) mecA 1251346..1252047 (+) 702 WP_004255173.1 adaptor protein MecA Regulator
  JRY11_RS06750 (JRY11_001356) - 1252050..1253381 (+) 1332 WP_021722251.1 MraY family glycosyltransferase -
  JRY11_RS06755 (JRY11_001357) sufC 1253556..1254326 (+) 771 WP_004255181.1 Fe-S cluster assembly ATPase SufC -
  JRY11_RS06760 (JRY11_001358) sufD 1254464..1255720 (+) 1257 WP_021722250.1 Fe-S cluster assembly protein SufD -
  JRY11_RS06765 (JRY11_001359) - 1255720..1256937 (+) 1218 WP_248554166.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 27077.46 Da        Isoelectric Point: 4.1246

>NTDB_id=539605 JRY11_RS06745 WP_004255173.1 1251346..1252047(+) (mecA) [Lactococcus lactis strain KF140]
MKYEDINENTIKITLSFDDLTDYDIKLSDFFGNQEVIEQFFYELVDELGLENRFGNVGMLTFQIQPFPQGVHMIVHEEAM
LGEGGEIPDDPEEFEELMTGFYNKLNEIGADMARERGITDFKPGLGLPGTKKDEAEQEPDFIYYSIRYEDIMSVLTGIKN
VKFADEESEFYRYDGNFYLVVLDNQKEKGKMHVESTRSRMMEYGEATKMSREFLQEYGECLIATRALDVLRKI

Nucleotide


Download         Length: 702 bp        

>NTDB_id=539605 JRY11_RS06745 WP_004255173.1 1251346..1252047(+) (mecA) [Lactococcus lactis strain KF140]
ATGAAATATGAGGATATAAACGAAAATACTATAAAAATCACCTTGTCTTTTGATGATTTGACAGATTATGATATCAAATT
ATCAGACTTTTTCGGAAATCAAGAAGTCATTGAACAATTTTTCTATGAATTGGTTGATGAGCTTGGTTTAGAAAATCGCT
TTGGAAATGTGGGAATGTTAACTTTCCAAATCCAACCTTTTCCTCAAGGTGTTCATATGATTGTTCATGAAGAAGCGATG
CTAGGTGAAGGTGGAGAAATTCCAGATGACCCAGAAGAGTTTGAAGAATTGATGACTGGTTTTTATAATAAATTAAATGA
AATAGGGGCAGATATGGCGCGCGAGCGAGGAATTACTGATTTTAAACCTGGGCTTGGTTTACCAGGAACAAAAAAAGACG
AAGCTGAACAAGAGCCAGATTTTATTTATTACTCTATTCGTTATGAAGATATTATGTCTGTCTTAACAGGAATAAAAAAT
GTGAAGTTTGCTGATGAAGAATCAGAGTTTTATCGTTATGATGGCAATTTTTATCTTGTTGTTTTGGATAATCAAAAAGA
AAAAGGCAAGATGCATGTTGAAAGTACCCGTTCACGAATGATGGAATATGGGGAAGCAACAAAAATGAGTCGAGAATTTT
TGCAGGAGTATGGTGAATGTCTTATCGCGACACGTGCTTTAGATGTTCTTAGAAAAATCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB S6FFV7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Lactococcus lactis subsp. lactis strain DGCC12653

99.571

100

0.996
  mecA Lactococcus lactis subsp. cremoris KW2

96.996

100

0.97