Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   LK450_RS04930 Genome accession   NZ_CP085939
Coordinates   1015924..1016556 (-) Length   210 a.a.
NCBI ID   WP_003031463.1    Uniprot ID   -
Organism   Streptococcus anginosus subsp. anginosus strain FDAARGOS_1569     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1010924..1021556
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LK450_RS04905 (LK450_04905) recX 1012149..1012925 (+) 777 WP_003031458.1 recombination regulator RecX -
  LK450_RS04910 (LK450_04910) - 1013012..1013545 (+) 534 WP_003031472.1 DUF402 domain-containing protein -
  LK450_RS04915 (LK450_04915) - 1013665..1013982 (+) 318 WP_003031462.1 DUF960 domain-containing protein -
  LK450_RS04920 (LK450_04920) - 1014108..1014482 (-) 375 WP_018543641.1 S1 RNA-binding domain-containing protein -
  LK450_RS04925 (LK450_04925) - 1014484..1015884 (-) 1401 WP_003031456.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  LK450_RS04930 (LK450_04930) vraR 1015924..1016556 (-) 633 WP_003031463.1 response regulator transcription factor Regulator
  LK450_RS04935 (LK450_04935) - 1016558..1017553 (-) 996 WP_003031470.1 sensor histidine kinase -
  LK450_RS04940 (LK450_04940) liaF 1017550..1018248 (-) 699 WP_003025810.1 cell wall-active antibiotics response protein LiaF -
  LK450_RS04945 (LK450_04945) stkP 1018509..1020383 (-) 1875 WP_018543640.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  LK450_RS04950 (LK450_04950) - 1020380..1021120 (-) 741 WP_003031460.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23689.21 Da        Isoelectric Point: 4.7341

>NTDB_id=539209 LK450_RS04930 WP_003031463.1 1015924..1016556(-) (vraR) [Streptococcus anginosus subsp. anginosus strain FDAARGOS_1569]
MHILLVDDHEMVRLGLKGYLDLQDDVDVVAEASNGREGVEKALELRSDVIMMDIVMPEMSGIEATLAILKEWPEAKILIL
TSYLDNEKIYPVLDAGAKGYMLKTSSADDILRAVRKVAKGELAIETEVSQKVEYHRNHIELHEDLTARERDILGLLAKGY
ENQRIADELFISLKTVKTHVSNILSKLEVSDRTQAVVYAFQHHLVPQDDI

Nucleotide


Download         Length: 633 bp        

>NTDB_id=539209 LK450_RS04930 WP_003031463.1 1015924..1016556(-) (vraR) [Streptococcus anginosus subsp. anginosus strain FDAARGOS_1569]
ATGCATATTTTATTAGTAGATGACCATGAAATGGTACGACTTGGCTTGAAAGGTTATTTGGATTTACAAGACGATGTGGA
TGTAGTGGCAGAAGCTTCAAATGGTCGCGAAGGAGTTGAAAAAGCTTTGGAGTTGCGCTCGGATGTGATTATGATGGACA
TTGTTATGCCTGAAATGAGTGGGATTGAAGCGACACTTGCTATTTTGAAAGAATGGCCTGAAGCTAAAATTCTCATTTTG
ACTTCTTATTTGGATAATGAAAAAATTTATCCGGTTTTAGACGCAGGTGCTAAAGGATATATGCTGAAAACATCTAGTGC
TGATGATATTTTACGAGCTGTCCGAAAAGTAGCTAAGGGTGAACTTGCCATTGAAACAGAGGTCAGCCAAAAAGTGGAAT
ATCATCGAAATCATATTGAATTGCACGAAGATTTGACTGCGCGTGAGCGAGATATTTTAGGACTACTGGCAAAAGGTTAT
GAAAATCAACGCATAGCAGATGAATTATTTATTTCTTTAAAGACAGTGAAAACACATGTGTCCAATATCTTATCAAAGCT
AGAAGTGAGCGATCGTACACAAGCTGTTGTTTATGCTTTCCAACATCACCTTGTCCCACAAGATGACATTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

53.883

98.095

0.529
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41