Detailed information
Bioinformatically predicted
Overview
| Name | ccrA | Type | Machinery gene |
| Locus tag | JQN76_RS03235 | Genome accession | NZ_CP070305 |
| Coordinates | 665289..666638 (+) | Length | 449 a.a. |
| NCBI ID | WP_001836585.1 | Uniprot ID | - |
| Organism | Staphylococcus sp. SM3655 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 635172..682175 | 665289..666638 | within | 0 |
| SCCmec | 660008..668287 | 665289..666638 | within | 0 |
Gene organization within MGE regions
Location: 635172..682175
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JQN76_RS03105 (JQN76_03105) | - | 635172..638324 (-) | 3153 | WP_001836569.1 | DEAD/DEAH box helicase | - |
| JQN76_RS03110 (JQN76_03110) | - | 638591..639193 (-) | 603 | WP_000908956.1 | hypothetical protein | - |
| JQN76_RS03115 (JQN76_03115) | - | 639401..639697 (-) | 297 | WP_000201644.1 | TfoX/Sxy family protein | - |
| JQN76_RS03120 (JQN76_03120) | - | 639746..639949 (-) | 204 | WP_000389759.1 | DUF6007 family protein | - |
| JQN76_RS03125 (JQN76_03125) | - | 640258..641244 (+) | 987 | WP_000662023.1 | tRNA-dihydrouridine synthase | - |
| JQN76_RS14160 | - | 641461..641642 (+) | 182 | Protein_605 | universal stress protein | - |
| JQN76_RS03135 (JQN76_03135) | sqr | 641910..643103 (-) | 1194 | WP_001033011.1 | type II sulfide:quinone oxidoreductase Sqr | - |
| JQN76_RS03140 (JQN76_03140) | cstB | 643122..644456 (-) | 1335 | WP_000465473.1 | persulfide dioxygenase-sulfurtransferase CstB | - |
| JQN76_RS03145 (JQN76_03145) | cstA | 644487..645554 (-) | 1068 | WP_001836572.1 | persulfide response sulfurtransferase CstA | - |
| JQN76_RS03150 (JQN76_03150) | cstR | 645691..645951 (+) | 261 | WP_001105089.1 | persulfide-sensing transcriptional repressor CstR | - |
| JQN76_RS03155 (JQN76_03155) | - | 645951..646706 (+) | 756 | WP_000355841.1 | sulfite exporter TauE/SafE family protein | - |
| JQN76_RS03160 (JQN76_03160) | - | 646804..646905 (+) | 102 | WP_001791873.1 | hypothetical protein | - |
| JQN76_RS03165 (JQN76_03165) | - | 646921..647373 (+) | 453 | Protein_612 | tRNA-dihydrouridine synthase | - |
| JQN76_RS03170 (JQN76_03170) | - | 647464..647967 (-) | 504 | WP_000575288.1 | hypothetical protein | - |
| JQN76_RS03175 (JQN76_03175) | - | 647960..648667 (-) | 708 | WP_000667076.1 | hypothetical protein | - |
| JQN76_RS03180 (JQN76_03180) | - | 648779..651907 (-) | 3129 | WP_001836570.1 | type I restriction endonuclease subunit R | - |
| JQN76_RS03185 (JQN76_03185) | - | 651891..653123 (-) | 1233 | WP_000394003.1 | restriction endonuclease subunit S | - |
| JQN76_RS03190 (JQN76_03190) | - | 653113..654627 (-) | 1515 | WP_000190898.1 | class I SAM-dependent DNA methyltransferase | - |
| JQN76_RS03195 (JQN76_03195) | - | 654666..655142 (-) | 477 | WP_001836567.1 | Pycsar system effector family protein | - |
| JQN76_RS03200 (JQN76_03200) | pycC | 655148..656419 (-) | 1272 | WP_000368660.1 | Pycsar phage resistance system cytidylate cyclase PycC | - |
| JQN76_RS03205 (JQN76_03205) | - | 656583..658796 (-) | 2214 | WP_205397782.1 | S8 family peptidase | - |
| JQN76_RS03210 (JQN76_03210) | - | 658789..659838 (-) | 1050 | WP_001836576.1 | ATP-binding protein | - |
| JQN76_RS03215 (JQN76_03215) | - | 660008..661522 (+) | 1515 | WP_001836559.1 | hypothetical protein | - |
| JQN76_RS03225 (JQN76_03225) | - | 662969..663262 (+) | 294 | WP_001836558.1 | single-stranded DNA-binding protein | - |
| JQN76_RS03230 (JQN76_03230) | - | 663262..665055 (+) | 1794 | WP_001836568.1 | DUF927 domain-containing protein | - |
| JQN76_RS03235 (JQN76_03235) | ccrA | 665289..666638 (+) | 1350 | WP_001836585.1 | recombinase family protein | Machinery gene |
| JQN76_RS03240 (JQN76_03240) | ccrB | 666660..668288 (+) | 1629 | WP_001836582.1 | recombinase family protein | Machinery gene |
| JQN76_RS03245 (JQN76_03245) | - | 668809..669159 (+) | 351 | WP_001836581.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| JQN76_RS03250 (JQN76_03250) | - | 669246..669557 (+) | 312 | WP_001836584.1 | DUF960 family protein | - |
| JQN76_RS03255 (JQN76_03255) | - | 669572..670075 (+) | 504 | WP_002494302.1 | DUF1643 domain-containing protein | - |
| JQN76_RS03260 (JQN76_03260) | - | 670089..670310 (+) | 222 | WP_001836575.1 | hypothetical protein | - |
| JQN76_RS03265 (JQN76_03265) | - | 670473..670883 (+) | 411 | WP_001836564.1 | DUF2871 domain-containing protein | - |
| JQN76_RS03270 (JQN76_03270) | - | 671551..672048 (+) | 498 | WP_000776433.1 | GNAT family N-acetyltransferase | - |
| JQN76_RS03275 (JQN76_03275) | - | 672313..672987 (-) | 675 | WP_001105999.1 | IS6-like element IS257 family transposase | - |
| JQN76_RS03280 (JQN76_03280) | - | 673415..673864 (+) | 450 | WP_001836863.1 | hypothetical protein | - |
| JQN76_RS03285 (JQN76_03285) | - | 674312..674755 (-) | 444 | WP_001836860.1 | hypothetical protein | - |
| JQN76_RS03290 (JQN76_03290) | - | 674811..675224 (-) | 414 | WP_001836859.1 | universal stress protein | - |
| JQN76_RS03295 (JQN76_03295) | - | 675238..676689 (-) | 1452 | WP_001836864.1 | SulP family inorganic anion transporter | - |
| JQN76_RS03300 (JQN76_03300) | - | 676803..677345 (+) | 543 | WP_001836856.1 | recombinase family protein | - |
| JQN76_RS03305 (JQN76_03305) | - | 677359..677613 (+) | 255 | WP_001836853.1 | hypothetical protein | - |
| JQN76_RS03310 (JQN76_03310) | mobC | 677974..678363 (+) | 390 | WP_001836861.1 | plasmid mobilization relaxosome protein MobC | - |
| JQN76_RS03315 (JQN76_03315) | - | 678339..678536 (+) | 198 | WP_001836858.1 | hypothetical protein | - |
| JQN76_RS03320 (JQN76_03320) | - | 678523..679533 (+) | 1011 | WP_001836862.1 | relaxase/mobilization nuclease domain-containing protein | - |
| JQN76_RS03325 (JQN76_03325) | - | 679646..680041 (+) | 396 | WP_001836857.1 | hypothetical protein | - |
| JQN76_RS03330 (JQN76_03330) | - | 680666..681460 (+) | 795 | WP_047210380.1 | RepB family plasmid replication initiator protein | - |
| JQN76_RS03335 (JQN76_03335) | - | 681501..682175 (-) | 675 | WP_001105999.1 | IS6-like element IS257 family transposase | - |
Sequence
Protein
Download Length: 449 a.a. Molecular weight: 52668.24 Da Isoelectric Point: 10.0062
>NTDB_id=539087 JQN76_RS03235 WP_001836585.1 665289..666638(+) (ccrA) [Staphylococcus sp. SM3655]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQMTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYRVHILSVHDGYFDMDQAFDRFKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYEYH
NGTFIINQNESPTVKGVFNYYLKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRSQKQTKQTPSDNQLKQKIKCPCCNATLTNMTVRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CRDFYQNQRIYTKIKSAIDKRIKRQRNIEKHHTLTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQHTIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQTMQSSIA
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQMTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYRVHILSVHDGYFDMDQAFDRFKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYEYH
NGTFIINQNESPTVKGVFNYYLKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRSQKQTKQTPSDNQLKQKIKCPCCNATLTNMTVRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CRDFYQNQRIYTKIKSAIDKRIKRQRNIEKHHTLTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQHTIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQTMQSSIA
Nucleotide
Download Length: 1350 bp
>NTDB_id=539087 JQN76_RS03235 WP_001836585.1 665289..666638(+) (ccrA) [Staphylococcus sp. SM3655]
ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAAGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAATGACACAATTAATTCAACAAGGACAATGTGACATATTATGCTGTTATCGTCTTAATAGGTTGCATCGTAAT
TTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACATATCGTGTTCATATCTTAAGTGTGCATGATGGTTATTTTGA
TATGGATCAAGCTTTCGACCGATTCAAGCTTAATATTTTTATCAGCTTGGCCGAACTTGAATCAGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACCCATGCGCCCTTTGGTTACGAATATCAC
AACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGGTGTATTCAATTATTACCTTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAATAATCAATATGGCCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATCGCAAAAACAAACCAAACAGACACCTTCGGATAACCAACTAAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACGAATATGACCGTTAGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCACGCTTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCCGAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAAGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACACATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATTGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACGTCAACAACCGCAACGCACTACATCTATCAATGGGCATCAAATACAACACACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATCGTCAATCAAACCATGCAATCATCAATTGCATAA
ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAAGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAATGACACAATTAATTCAACAAGGACAATGTGACATATTATGCTGTTATCGTCTTAATAGGTTGCATCGTAAT
TTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACATATCGTGTTCATATCTTAAGTGTGCATGATGGTTATTTTGA
TATGGATCAAGCTTTCGACCGATTCAAGCTTAATATTTTTATCAGCTTGGCCGAACTTGAATCAGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACCCATGCGCCCTTTGGTTACGAATATCAC
AACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGGTGTATTCAATTATTACCTTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAATAATCAATATGGCCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATCGCAAAAACAAACCAAACAGACACCTTCGGATAACCAACTAAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACGAATATGACCGTTAGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCACGCTTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCCGAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAAGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACACATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATTGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACGTCAACAACCGCAACGCACTACATCTATCAATGGGCATCAAATACAACACACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATCGTCAATCAAACCATGCAATCATCAATTGCATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrA | Staphylococcus aureus N315 |
97.996 |
100 |
0.98 |
| ccrA | Staphylococcus aureus COL |
75.056 |
100 |
0.751 |