Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   SPB_RS05480 Genome accession   NZ_AEUT02000001
Coordinates   1091979..1092620 (-) Length   213 a.a.
NCBI ID   WP_003105505.1    Uniprot ID   -
Organism   Streptococcus parauberis NCFD 2020     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1086979..1097620
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPB_RS05455 (SPB_1130) comFA/cflA 1087072..1088376 (-) 1305 WP_003104831.1 DEAD/DEAH box helicase Machinery gene
  SPB_RS05460 (SPB_1131) - 1088433..1089065 (+) 633 WP_003105463.1 YigZ family protein -
  SPB_RS05465 (SPB_1132) cysK 1089188..1090117 (+) 930 WP_003103108.1 cysteine synthase A -
  SPB_RS05470 (SPB_1133) - 1090193..1090546 (-) 354 WP_003103672.1 S1 RNA-binding domain-containing protein -
  SPB_RS05475 (SPB_1134) - 1090546..1091946 (-) 1401 WP_003104279.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  SPB_RS05480 (SPB_1135) vraR 1091979..1092620 (-) 642 WP_003105505.1 response regulator transcription factor Regulator
  SPB_RS05485 (SPB_1136) - 1092613..1093617 (-) 1005 WP_003104853.1 sensor histidine kinase -
  SPB_RS05490 (SPB_1137) liaF 1093614..1094309 (-) 696 WP_037620823.1 cell wall-active antibiotics response protein LiaF -
  SPB_RS05495 (SPB_1138) pknB 1094460..1096193 (-) 1734 WP_003103640.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  SPB_RS05500 (SPB_1139) - 1096193..1096933 (-) 741 WP_003102848.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23929.59 Da        Isoelectric Point: 4.7106

>NTDB_id=53816 SPB_RS05480 WP_003105505.1 1091979..1092620(-) (vraR) [Streptococcus parauberis NCFD 2020]
MDKIRVILVDDHEMVRLGLKSFLNMQKDIEVIGEASNGRQGIDLALELRPDVLVMDLVMPEMGGVEATLDILSKWTEAKV
LVLTSYLDNEKIYPVIDAGAKGYMLKTSSAAEILNAIKKVAKGQLAIETEVDKKIKEHDKNPELHEELTAREFDILYLLA
KGYDNQTIADELFISLKTVKTHVSNILSKLDVDDRTQAVVYAFQHHIVPQDDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=53816 SPB_RS05480 WP_003105505.1 1091979..1092620(-) (vraR) [Streptococcus parauberis NCFD 2020]
ATGGATAAAATACGTGTCATATTAGTTGATGACCATGAGATGGTGCGTTTAGGCTTAAAAAGCTTCTTAAATATGCAAAA
AGACATTGAAGTTATTGGTGAAGCATCTAATGGTCGCCAAGGCATTGATTTAGCTTTAGAACTACGTCCAGATGTTTTAG
TCATGGATTTAGTGATGCCTGAAATGGGTGGAGTTGAAGCGACATTAGATATTCTTTCAAAATGGACGGAAGCTAAAGTT
TTAGTACTGACTTCCTATCTTGATAATGAGAAAATCTATCCAGTTATTGATGCCGGAGCCAAAGGTTATATGTTAAAGAC
TTCAAGTGCTGCAGAAATCTTAAATGCAATTAAAAAAGTAGCAAAAGGCCAACTAGCTATTGAGACAGAAGTTGACAAAA
AAATTAAAGAGCATGATAAAAATCCAGAATTGCATGAGGAGTTAACAGCTCGGGAATTTGATATTTTATATCTGTTAGCC
AAAGGATATGATAATCAAACGATTGCTGATGAGTTATTTATTTCATTAAAAACTGTAAAAACACATGTTTCAAATATTCT
TTCTAAATTGGATGTCGACGATCGAACACAAGCTGTAGTCTACGCATTCCAACACCATATAGTGCCACAAGATGACAATT
AA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-118)

Bacterial regulatory proteins, luxR family (GerE)

(148-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.427

96.714

0.507
  degU Bacillus subtilis subsp. subtilis str. 168

36.036

100

0.376

Multiple sequence alignment