Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   LIN99_RS00525 Genome accession   NZ_CP085093
Coordinates   102382..103071 (+) Length   229 a.a.
NCBI ID   WP_005547547.1    Uniprot ID   -
Organism   Aggregatibacter actinomycetemcomitans strain 23S     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 97382..108071
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LIN99_RS00500 nanQ 97661..98131 (+) 471 WP_005547536.1 N-acetylneuraminate anomerase -
  LIN99_RS00505 ampD 98605..99159 (-) 555 WP_005567973.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  LIN99_RS00510 pilA 99281..99733 (+) 453 WP_005586498.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  LIN99_RS00515 pilB 99760..101169 (+) 1410 WP_005567970.1 GspE/PulE family protein Machinery gene
  LIN99_RS00520 pilC 101162..102385 (+) 1224 WP_005567968.1 type II secretion system F family protein Machinery gene
  LIN99_RS00525 pilD 102382..103071 (+) 690 WP_005547547.1 A24 family peptidase Machinery gene
  LIN99_RS00530 coaE 103121..103744 (+) 624 WP_005547548.1 dephospho-CoA kinase -
  LIN99_RS00535 yacG 103734..103946 (+) 213 WP_005567966.1 DNA gyrase inhibitor YacG -
  LIN99_RS00540 - 103946..104218 (+) 273 WP_005547552.1 GNAT family N-acetyltransferase -
  LIN99_RS00545 - 104615..105988 (+) 1374 WP_005547554.1 sodium:alanine symporter family protein -
  LIN99_RS00550 raiA 106216..106539 (+) 324 WP_005540708.1 ribosome-associated translation inhibitor RaiA -
  LIN99_RS00555 - 106688..107242 (+) 555 WP_005540709.1 DUF5358 domain-containing protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26018.72 Da        Isoelectric Point: 8.2297

>NTDB_id=537657 LIN99_RS00525 WP_005547547.1 102382..103071(+) (pilD) [Aggregatibacter actinomycetemcomitans strain 23S]
MMWLLFLLGGALCGWRVHRYVEHFADNLSREVHAAYTEIYPQNPPHFTAEKSILKPLKRHFSAPLYSLLFTLLFIICYAI
NEPLQALCFALYGALLIAISLVDWHYRLISPALCQALFTLGLGAAYWQIGTLTLEQSLQSAVVFFGVFYAIYHAAKWYYR
QEALGRGDYWLALGLGVFLPAHQFPVFLFLACFFGLLYAAYAKYQHRTLNAVPFGPFMSLAGVVCLLLN

Nucleotide


Download         Length: 690 bp        

>NTDB_id=537657 LIN99_RS00525 WP_005547547.1 102382..103071(+) (pilD) [Aggregatibacter actinomycetemcomitans strain 23S]
ATGATGTGGCTACTTTTTTTGCTTGGTGGCGCACTATGCGGGTGGCGTGTTCATCGTTATGTAGAACATTTCGCCGATAA
CCTCAGCCGCGAGGTTCATGCCGCCTACACGGAAATTTACCCGCAAAACCCACCGCACTTTACAGCGGAAAAGTCGATTC
TGAAACCGCTTAAACGGCATTTTTCCGCGCCCCTTTACAGCCTTTTATTCACCTTGCTGTTCATTATTTGTTATGCCATC
AATGAACCGTTACAAGCCCTATGCTTTGCCCTTTATGGCGCCTTATTAATTGCCATTTCCCTAGTGGATTGGCACTATCG
CTTGATTTCACCCGCCTTATGCCAAGCCTTGTTTACCCTCGGTTTAGGCGCGGCATACTGGCAAATCGGCACATTAACAT
TGGAGCAAAGCCTGCAAAGTGCGGTTGTTTTTTTCGGTGTTTTTTATGCCATCTACCACGCCGCAAAATGGTACTACCGA
CAAGAAGCTCTCGGACGCGGCGATTATTGGTTGGCACTGGGCTTAGGCGTTTTTCTCCCGGCACACCAATTTCCTGTTTT
TTTATTCCTCGCCTGCTTTTTCGGCTTACTTTATGCTGCCTACGCCAAATACCAACATCGCACACTCAACGCCGTGCCTT
TCGGTCCCTTTATGTCCCTAGCCGGCGTGGTCTGTTTATTGCTTAATTGA

Domains

Predicted by InterProScan.

Type IV leader peptidase family (Peptidase_A24)

(94-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Haemophilus influenzae 86-028NP

39.301

100

0.393
  pilD Haemophilus influenzae Rd KW20

38.839

97.817

0.38