Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   LIO33_RS02030 Genome accession   NZ_CP085088
Coordinates   404158..404799 (+) Length   213 a.a.
NCBI ID   WP_002937025.1    Uniprot ID   A0A0H3MTV8
Organism   Streptococcus suis strain Ssuis_MA1     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 399158..409799
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LIO33_RS02010 - 399326..400063 (+) 738 WP_172005019.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  LIO33_RS02015 pknB 400063..401721 (+) 1659 Protein_358 Stk1 family PASTA domain-containing Ser/Thr kinase -
  LIO33_RS09710 - 401842..402057 (+) 216 Protein_359 serine/threonine protein kinase -
  LIO33_RS02020 liaF 402514..403173 (+) 660 WP_223375661.1 cell wall-active antibiotics response protein LiaF -
  LIO33_RS02025 - 403170..404186 (+) 1017 WP_002937028.1 sensor histidine kinase -
  LIO33_RS02030 vraR 404158..404799 (+) 642 WP_002937025.1 response regulator transcription factor Regulator
  LIO33_RS02035 - 404849..406249 (+) 1401 WP_011921996.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  LIO33_RS02040 - 406251..406622 (+) 372 WP_011921997.1 S1 RNA-binding domain-containing protein -
  LIO33_RS02045 cysK 406648..407574 (-) 927 WP_012774985.1 cysteine synthase A -
  LIO33_RS02050 - 407664..408296 (-) 633 WP_014636235.1 YigZ family protein -
  LIO33_RS02055 comFA/cflA 408353..409645 (+) 1293 WP_043028911.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23790.36 Da        Isoelectric Point: 4.8970

>NTDB_id=537385 LIO33_RS02030 WP_002937025.1 404158..404799(+) (vraR) [Streptococcus suis strain Ssuis_MA1]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAKALEVKPDVVVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILAAIRKVALGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=537385 LIO33_RS02030 WP_002937025.1 404158..404799(+) (vraR) [Streptococcus suis strain Ssuis_MA1]
ATGAATACGATTCGAGTGATGCTGGTTGACGACCATGAGATGGTTCGCCTAGGATTGAAAAGTTACTTAAATTTACAGCC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAAGGTTTGGCTAAAGCGTTAGAGGTTAAACCTGATGTTGTAG
TGATGGACTTGGTTATGCCCAAGATGACTGGCGTAGAAGCAACTCTGGCCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACCTCCTATCTAGATAATGAGAAAATCTATCCTGTGCTGGAAGCAGGAGCTCGTGGCTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGCAGCCATCCGCAAGGTAGCTCTTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACTTGACAGCTCGTGAACGCGAAATCTTGACGCTGTTAGCC
AAGGGATATGATAATCAACGAATTGCAGATGAGTCCTTCATATCCTTAAAAACTGTTAAGACCCATGTTTCCAATATCTT
ATCCAAACTAGCTGTTAGCGATCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGAGGACCAAT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MTV8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.589

97.183

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.938

100

0.413