Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   I6K87_RS00115 Genome accession   NZ_CP069892
Coordinates   19918..20607 (+) Length   229 a.a.
NCBI ID   WP_022526966.1    Uniprot ID   -
Organism   Streptococcus anginosus strain FDAARGOS_1357     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 14918..25607
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6K87_RS00085 (I6K87_00085) - 15290..15829 (+) 540 WP_003029925.1 DUF177 domain-containing protein -
  I6K87_RS00090 (I6K87_00090) - 15952..16179 (-) 228 WP_003029926.1 hypothetical protein -
  I6K87_RS00095 (I6K87_00095) - 16179..16907 (-) 729 WP_003029927.1 ABC transporter permease -
  I6K87_RS00100 (I6K87_00100) - 16891..17625 (-) 735 WP_003029928.1 ABC transporter ATP-binding protein -
  I6K87_RS00105 (I6K87_00105) - 17615..18280 (-) 666 WP_049534658.1 TetR/AcrR family transcriptional regulator -
  I6K87_RS00110 (I6K87_00110) gndA 18485..19909 (+) 1425 WP_059221018.1 NADP-dependent phosphogluconate dehydrogenase -
  I6K87_RS00115 (I6K87_00115) covR 19918..20607 (+) 690 WP_022526966.1 response regulator transcription factor Regulator
  I6K87_RS00120 (I6K87_00120) - 20819..23008 (+) 2190 WP_049534654.1 PTS transporter subunit IIBC -
  I6K87_RS00125 (I6K87_00125) - 23025..23840 (+) 816 WP_003029933.1 endonuclease/exonuclease/phosphatase family protein -
  I6K87_RS00130 (I6K87_00130) - 23887..24498 (-) 612 WP_022525076.1 hypothetical protein -
  I6K87_RS00135 (I6K87_00135) nrdR 24665..25138 (+) 474 WP_003029936.1 transcriptional regulator NrdR -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26500.61 Da        Isoelectric Point: 6.2732

>NTDB_id=537227 I6K87_RS00115 WP_022526966.1 19918..20607(+) (covR) [Streptococcus anginosus strain FDAARGOS_1357]
MAKRILLVEKEKKLAQFIGLELQKEGYRVDLFETGKDALASARANQYDLFLLNFMLDDMTGTEFAAQLSVIKPASVIIVL
DNRDNILQYTEEIQRFAVAYMVEPFIVTDLVEKISAIFRGRDFIDQHCSQMKVPTSYRNLRIDVQNHTVYRGEEVIALTR
REYDLLATLMGSHQALSREQLLERVWKYEGAVETNVVDVYIRYLRSKIDIVGQKSYIKTVRGVGYVMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=537227 I6K87_RS00115 WP_022526966.1 19918..20607(+) (covR) [Streptococcus anginosus strain FDAARGOS_1357]
ATGGCGAAGCGGATTTTATTAGTTGAGAAAGAAAAAAAATTAGCGCAATTTATTGGCTTAGAGCTACAAAAAGAAGGTTA
TCGAGTTGATCTTTTTGAAACAGGAAAAGATGCTTTGGCGTCTGCGAGAGCTAATCAATACGATTTATTCCTGTTGAATT
TTATGCTTGACGATATGACAGGAACAGAATTTGCCGCACAATTAAGTGTGATAAAGCCTGCTTCGGTCATCATTGTATTG
GATAATCGTGATAATATTCTTCAATATACTGAGGAAATCCAACGCTTTGCTGTTGCTTACATGGTAGAACCATTCATTGT
GACGGACTTAGTTGAAAAAATTTCTGCCATTTTTCGTGGGCGTGATTTTATTGACCAGCATTGTAGTCAGATGAAAGTTC
CAACATCTTATCGGAATCTTCGGATTGATGTGCAAAATCATACAGTTTATCGAGGTGAAGAAGTGATTGCTTTGACTCGA
AGAGAGTATGATTTATTAGCAACATTGATGGGAAGTCATCAGGCTTTAAGCCGTGAACAGTTGTTAGAACGCGTGTGGAA
ATACGAAGGAGCTGTTGAAACAAATGTTGTCGATGTTTATATTCGCTATCTTCGTAGTAAAATTGATATAGTGGGGCAAA
AAAGTTATATAAAAACCGTGCGTGGTGTTGGTTATGTTATGCAAGAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.696

100

0.489
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.852

100

0.459