Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/comE1   Type   Machinery gene
Locus tag   JS559_RS08245 Genome accession   NZ_CP069795
Coordinates   1751578..1751922 (-) Length   114 a.a.
NCBI ID   WP_005599904.1    Uniprot ID   A3N254
Organism   Actinobacillus pleuropneumoniae strain A-85/14     
Function   dsDNA binding (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1746578..1756922
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JS559_RS08230 (JS559_08230) - 1747393..1748013 (+) 621 WP_005619829.1 MerR family transcriptional regulator -
  JS559_RS08235 (JS559_08235) gshAB 1748105..1750378 (-) 2274 WP_237611463.1 bifunctional glutamate--cysteine ligase GshA/glutathione synthetase GshB -
  JS559_RS08240 (JS559_08240) asd 1750534..1751427 (-) 894 WP_005612934.1 archaetidylserine decarboxylase -
  JS559_RS08245 (JS559_08245) comEA/comE1 1751578..1751922 (-) 345 WP_005599904.1 ComEA family DNA-binding protein Machinery gene
  JS559_RS08250 (JS559_08250) - 1752223..1753614 (+) 1392 WP_237611464.1 LysM-like peptidoglycan-binding domain-containing protein -
  JS559_RS08255 (JS559_08255) - 1753736..1754140 (+) 405 WP_005599908.1 MliC family protein -
  JS559_RS08260 (JS559_08260) waaF 1754222..1755259 (+) 1038 WP_005619838.1 lipopolysaccharide heptosyltransferase II -
  JS559_RS08265 (JS559_08265) rfaC 1755334..1756293 (+) 960 WP_005602025.1 lipopolysaccharide heptosyltransferase RfaC -
  JS559_RS08270 (JS559_08270) rpsL 1756415..1756789 (+) 375 WP_005543325.1 30S ribosomal protein S12 -

Sequence

Protein


Download         Length: 114 a.a.        Molecular weight: 12446.30 Da        Isoelectric Point: 10.2030

>NTDB_id=536670 JS559_RS08245 WP_005599904.1 1751578..1751922(-) (comEA/comE1) [Actinobacillus pleuropneumoniae strain A-85/14]
MKKFARFSISFIIALLSADSIAKPNNPPVSEPTPVVQQMTTTNKTADKQNQVNINTADAAEIKSKLVGIGEKKAQAIVDY
RTKNGAFITIEQLTEVSGIGKATLEKNRERITLE

Nucleotide


Download         Length: 345 bp        

>NTDB_id=536670 JS559_RS08245 WP_005599904.1 1751578..1751922(-) (comEA/comE1) [Actinobacillus pleuropneumoniae strain A-85/14]
ATGAAAAAATTTGCCCGATTTAGTATTAGCTTCATCATTGCATTGTTATCCGCCGATTCAATCGCAAAGCCTAATAATCC
GCCCGTTTCCGAACCGACTCCCGTAGTTCAACAAATGACAACAACGAACAAAACTGCCGATAAACAAAATCAAGTGAATA
TCAATACGGCGGATGCAGCGGAAATTAAATCCAAACTGGTGGGAATCGGTGAGAAAAAAGCACAAGCGATTGTCGATTAC
CGCACTAAAAACGGTGCTTTTATTACGATAGAACAACTAACGGAAGTCTCCGGAATCGGTAAAGCGACACTAGAGAAAAA
TCGCGAACGCATCACGTTAGAATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(48-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A3N254

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/comE1 Glaesserella parasuis strain SC1401

58.261

100

0.588
  comE1/comEA Haemophilus influenzae Rd KW20

47.115

91.228

0.43