Detailed information NTG0536621

Bioinformatically predicted

Overview

• Name: cytR
• Type: Regulator
• Locus tag: LHK10_RS22460
• Genome accession: NZ_CP085056
• Coordinates: 4648765..4649790 (+)
• Length: 341 a.a.
• NCBI ID: WP_000644904.1
• Uniprot ID: P0ACN8
• Organism: Escherichia coli strain P24_WM1_05.20
• Function: promote competence gene expression (predicted from homology) Competence regulation

Genomic Context

Location: 4643765..4654790

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LHK10_RS22450 (LHK10_22450)	rpmE	4645996..4646208 (-)	213	WP_000710769.1	50S ribosomal protein L31	-
LHK10_RS22455 (LHK10_22455)	priA	4646411..4648609 (+)	2199	WP_001324365.1	primosomal protein N'	Machinery gene
LHK10_RS22460 (LHK10_22460)	cytR	4648765..4649790 (+)	1026	WP_000644904.1	DNA-binding transcriptional regulator CytR	Regulator
LHK10_RS22465 (LHK10_22465)	ftsN	4649882..4650841 (+)	960	WP_000068837.1	cell division protein FtsN	-
LHK10_RS22470 (LHK10_22470)	hslV	4650934..4651464 (+)	531	WP_000208242.1	ATP-dependent protease subunit HslV	-
LHK10_RS22475 (LHK10_22475)	hslU	4651474..4652805 (+)	1332	WP_001293341.1	HslU--HslV peptidase ATPase subunit	-
LHK10_RS22480 (LHK10_22480)	menA	4652872..4653798 (+)	927	WP_000139496.1	1,4-dihydroxy-2-naphthoate polyprenyltransferase	-
LHK10_RS22485 (LHK10_22485)	rraA	4653891..4654376 (+)	486	WP_000872908.1	ribonuclease E activity regulator RraA	-
LHK10_RS22490 (LHK10_22490)	zapB	4654461..4654706 (-)	246	WP_001296623.1	septal ring assembly protein ZapB	-

Sequence

Protein

• Length: 341 a.a.
• Molecular weight: 37819.78 Da
• Isoelectric Point: 6.3842

>NTDB_id=536621 LHK10_RS22460 WP_000644904.1 4648765..4649790(+) (cytR) [Escherichia coli strain P24_WM1_05.20]
MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDP
FFSEIIRGIEVTAANHGYLVLIGDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVDPQYIARGDFTFEAGSKAMQQLL
DLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLSIIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHV
GSGSRLMDCELIIRGSTRALP

Nucleotide

• Length: 1026 bp

>NTDB_id=536621 LHK10_RS22460 WP_000644904.1 4648765..4649790(+) (cytR) [Escherichia coli strain P24_WM1_05.20]
GTGAAAGCGAAGAAGCAGGAAACTGCCGCGACCATGAAAGACGTTGCCCTCAAGGCAAAAGTCTCTACAGCGACTGTCTC
CCGAGCATTAATGAATCCCGATAAAGTCTCCCAGGCCACCCGTAATCGGGTTGAAAAAGCGGCCCGGGAAGTGGGTTATT
TACCGCAACCTATGGGGCGCAACGTCAAGCGTAATGAATCCCGCACCATTCTGGTGATTGTCCCGGATATCTGCGATCCC
TTCTTTAGCGAAATTATTCGCGGTATCGAAGTTACGGCGGCAAATCACGGATATCTGGTGCTGATTGGCGACTGTGCGCA
TCAAAATCAGCAGGAAAAAACCTTTATCGATTTGATCATCACCAAGCAAATTGATGGCATGTTGCTGCTGGGCTCAAGGC
TGCCGTTTGATGCCAGCATTGAGGAACAGCGTAATCTGCCGCCGATGGTGATGGCGAACGAATTTGCACCGGAACTGGAG
CTGCCTACCGTTCATATCGACAATCTGACCGCCGCATTTGATGCAGTAAATTATTTATATGAGCAAGGGCATAAACGGAT
TGGCTGTATAGCCGGTCCCGAAGAGATGCCACTGTGTCACTACCGCCTGCAAGGCTATGTTCAGGCGCTGCGTCGCTGCG
GCATTATGGTTGATCCGCAATACATCGCCCGTGGCGACTTCACCTTCGAAGCCGGAAGCAAAGCGATGCAGCAGCTGCTT
GATCTTCCACAACCGCCTACTGCTGTCTTCTGCCATAGCGATGTGATGGCGCTCGGCGCACTTTCTCAGGCAAAACGCCA
GGGGCTGAAAGTCCCGGAAGACCTTTCCATAATCGGTTTTGATAACATCGACCTGACGCAATTTTGTGATCCGCCGCTGA
CAACCATCGCGCAGCCGCGTTACGAAATCGGTCGGGAAGCTATGCTGTTATTGCTTGATCAAATGCAGGGGCAACACGTT
GGCAGTGGCTCTCGTTTAATGGACTGCGAACTTATCATCCGGGGATCAACACGCGCGTTACCTTAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (11-56)

• Periplasmic binding protein-like domain (Peripla_BP_3) (176-337)

3D structure

• AlphaFold DB: P0ACN8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cytR	Vibrio parahaemolyticus RIMD 2210633	64.179	98.24	0.63
cytR	Vibrio cholerae C6706	65.443	95.894	0.628