Detailed information NTG0536481

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: LH646_RS27555
• Genome accession: NZ_CP085039
• Coordinates: 6270101..6271222 (+)
• Length: 373 a.a.
• NCBI ID: WP_010645237.1
• Uniprot ID: A0A385DDD7
• Organism: Streptomyces sp. WA1-19
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 6265101..6276222

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LH646_RS27540 (LH646_27540)	-	6265902..6267623 (-)	1722	WP_175457492.1	BACON domain-containing protein	-
LH646_RS27545 (LH646_27545)	-	6267882..6268457 (+)	576	WP_030699876.1	dihydrofolate reductase family protein	-
LH646_RS27550 (LH646_27550)	radA/sms	6268512..6269930 (+)	1419	WP_003948876.1	DNA repair protein RadA	Machinery gene
LH646_RS27555 (LH646_27555)	disA	6270101..6271222 (+)	1122	WP_010645237.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
LH646_RS27560 (LH646_27560)	-	6271305..6272114 (-)	810	WP_226965416.1	hypothetical protein	-
LH646_RS27565 (LH646_27565)	-	6272471..6273220 (+)	750	WP_030699878.1	phosphatase PAP2 family protein	-
LH646_RS27570 (LH646_27570)	-	6273333..6274385 (+)	1053	WP_047470995.1	A/G-specific adenine glycosylase	-
LH646_RS27575 (LH646_27575)	-	6274604..6275143 (+)	540	WP_030698866.1	SigE family RNA polymerase sigma factor	-
LH646_RS27580 (LH646_27580)	-	6275164..6275832 (+)	669	WP_030698867.1	lipoprotein	-

Sequence

Protein

• Length: 373 a.a.
• Molecular weight: 40215.10 Da
• Isoelectric Point: 5.1034

>NTDB_id=536481 LH646_RS27555 WP_010645237.1 6270101..6271222(+) (disA) [Streptomyces sp. WA1-19]
MAANDRATAPGKSGGPGADGLMRASLSAVAPGTQLRDGLERILRGNTGGLIVLGWDKTVESMCTGGFVLDVEFSATRLRE
LCKLDGGIVLDKDLTKILRAGVQLVPDPTIPTDETGTRHRTADRVSKQVNFPVVSVSQSMRLIALYVDGQRRVLEDSAAI
LSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVSQRLEMVRRIAAEIAEYVVELGTDGRLLALQLDELIAG
VEPERELVVRDYVPEPTAKRSRTVDEALAELGKLSHTELLELPVVARALGYTGSPEALDSAVSPRGFRLLAKVPRLPGAI
IDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1122 bp

>NTDB_id=536481 LH646_RS27555 WP_010645237.1 6270101..6271222(+) (disA) [Streptomyces sp. WA1-19]
GTGGCAGCCAATGACCGGGCAACGGCCCCCGGCAAGTCCGGCGGGCCCGGTGCCGACGGGCTGATGCGTGCCTCGCTGAG
CGCCGTCGCCCCCGGCACCCAGCTGCGGGACGGGCTGGAGCGGATTCTGCGGGGGAACACCGGCGGACTCATCGTGCTCG
GCTGGGACAAGACCGTCGAGTCGATGTGTACCGGCGGCTTCGTGCTGGACGTCGAGTTCTCCGCGACCCGCCTGCGCGAG
CTGTGCAAGCTCGACGGCGGCATCGTCCTCGACAAGGACCTCACCAAGATCCTGCGCGCCGGAGTCCAGCTCGTCCCCGA
CCCGACCATCCCCACCGACGAGACCGGCACCCGGCACCGCACCGCCGACCGCGTCTCCAAGCAGGTCAACTTCCCCGTGG
TCTCGGTCAGCCAGTCGATGCGGCTGATCGCGCTCTACGTGGACGGGCAGCGCCGGGTCCTGGAGGACTCGGCCGCCATC
CTCTCCCGCGCCAACCAGGCTCTCGCCACATTGGAGCGGTACAAGCTCCGGCTGGACGAGGTGGCCGGCACGCTCTCGGC
GCTGGAGATCGAGGACCTGGTCACGGTCCGCGACGTCACGGCCGTCTCGCAGCGGCTGGAGATGGTCCGCCGGATCGCCG
CCGAGATCGCCGAGTACGTGGTGGAACTGGGCACCGACGGGCGGCTGCTCGCCCTCCAGCTGGACGAACTGATCGCCGGC
GTCGAGCCCGAACGCGAGCTGGTCGTCCGGGACTACGTGCCGGAGCCCACGGCGAAGCGTTCCCGCACGGTGGACGAGGC
GCTGGCGGAGCTGGGCAAGCTCAGCCACACCGAGTTGCTCGAACTCCCCGTGGTGGCGCGGGCGCTCGGCTACACCGGCT
CGCCGGAGGCGCTGGACTCGGCGGTGTCGCCGCGCGGCTTCCGCCTCCTGGCGAAGGTGCCGAGGCTGCCCGGCGCCATC
ATCGACCGGCTGGTGGAGCACTTCGGCGGCCTCCAGAAGCTGCTGGCGGCCAGCGTGGACGACCTCCAGACGGTGGACGG
CGTTGGCGAGGCCCGTGCCCGCAGCGTCCGCGAGGGCCTCTCCCGCCTGGCCGAGTCGTCGATCCTGGAGCGGTACGTCT
GA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (37-150)

• DisA bacterial checkpoint controller linker region (DisA-linker) (154-296)

• Helix-hairpin-helix motif (HHH_2) (323-358)

3D structure

• AlphaFold DB: A0A385DDD7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	46.532	92.761	0.432