Detailed information NTG0535634

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: I6J35_RS03330
• Genome accession: NZ_CP069567
• Coordinates: 681283..682326 (+)
• Length: 347 a.a.
• NCBI ID: WP_047132847.1
• Uniprot ID: A0A143P7E7
• Organism: Staphylococcus condimenti strain FDAARGOS_1205
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 676283..687326

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6J35_RS03305 (I6J35_03305)	-	677264..677989 (+)	726	WP_047132842.1	type 1 glutamine amidotransferase	-
I6J35_RS03310 (I6J35_03310)	-	678039..679025 (-)	987	WP_047132843.1	FUSC family protein	-
I6J35_RS03315 (I6J35_03315)	map	679273..680040 (+)	768	WP_047132844.1	type I methionyl aminopeptidase	-
I6J35_RS03320 (I6J35_03320)	-	680174..680569 (+)	396	WP_047132845.1	hypothetical protein	-
I6J35_RS03325 (I6J35_03325)	liaF	680585..681286 (+)	702	WP_047132846.1	cell wall-active antibiotics response protein LiaF	-
I6J35_RS03330 (I6J35_03330)	vraS	681283..682326 (+)	1044	WP_047132847.1	sensor histidine kinase	Regulator
I6J35_RS03335 (I6J35_03335)	vraR	682316..682945 (+)	630	WP_047132848.1	response regulator transcription factor	Regulator
I6J35_RS03340 (I6J35_03340)	-	682994..683572 (-)	579	WP_047132849.1	beta-class carbonic anhydrase	-
I6J35_RS03345 (I6J35_03345)	-	683774..684850 (-)	1077	WP_047132850.1	YihY/virulence factor BrkB family protein	-
I6J35_RS03350 (I6J35_03350)	-	684970..685266 (-)	297	WP_047132851.1	hypothetical protein	-
I6J35_RS03355 (I6J35_03355)	-	685274..685738 (-)	465	WP_047132852.1	low molecular weight protein-tyrosine-phosphatase	-
I6J35_RS03360 (I6J35_03360)	-	685974..686180 (+)	207	WP_047132853.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40101.54 Da
• Isoelectric Point: 5.0629

>NTDB_id=535634 I6J35_RS03330 WP_047132847.1 681283..682326(+) (vraS) [Staphylococcus condimenti strain FDAARGOS_1205]
MNHYIRAIGSMLILIYSILAIFFFIDKVFVNIVFFQGMFYTQIFGIPVFLFLNIIVILMCIIVGSVLAYKVNQQNHWIKD
QIEHSIEGEVVGINDQNIELYQETLDIYHMLVPLNQELHRLRIKTQDLTNETYNLNDTKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPTLEKMVQDSQLEMRALLLHLRPLGLKDRSLGEGIKDLVVDLQKKVPMKVVYDI
EDFEVPKGIEDHLFRITQEGISNTLRHAEGTKLTIDLYNKDDYLLLRIQDDGKGFDVDEKMEKSYGLKNMRERALEIGAT
LHIVSLPGAGTRIEVKAPLNKEEFDDD

Nucleotide

• Length: 1044 bp

>NTDB_id=535634 I6J35_RS03330 WP_047132847.1 681283..682326(+) (vraS) [Staphylococcus condimenti strain FDAARGOS_1205]
ATGAACCATTATATAAGAGCGATAGGTTCAATGTTAATATTGATTTACAGCATTTTAGCTATTTTCTTTTTCATCGATAA
AGTCTTTGTAAATATTGTCTTTTTTCAAGGAATGTTCTATACACAAATTTTCGGAATTCCAGTTTTTTTGTTTTTAAATA
TCATTGTAATATTGATGTGTATTATCGTAGGTTCTGTATTAGCGTATAAAGTGAACCAGCAAAATCATTGGATTAAAGAC
CAAATTGAACATTCTATTGAAGGTGAAGTCGTAGGTATTAATGATCAAAATATCGAACTTTATCAAGAGACGTTAGATAT
CTATCATATGTTGGTACCTTTAAATCAAGAATTGCACCGCTTACGTATTAAAACACAAGATTTAACGAATGAAACTTATA
ATTTAAATGATACAAAAGTAAAAAAAATTATAGAAGATGAACGTCAACGTTTAGCAAGAGAACTGCATGACTCGGTGAGC
CAGCAATTATTTGCTGCAAGTATGATGTTGTCTGCTATAAAGGAAACTAAGTTAGAACCGCCTTTAGATCAACAAATTCC
AACACTTGAAAAGATGGTACAAGATTCACAACTTGAAATGCGTGCTTTATTGCTTCATTTACGTCCATTAGGCTTAAAGG
ACCGTTCATTAGGTGAAGGTATTAAAGACTTGGTTGTAGACTTGCAGAAAAAAGTTCCGATGAAGGTAGTTTATGATATC
GAAGATTTTGAAGTGCCAAAAGGGATAGAAGATCATTTATTCCGAATAACACAAGAAGGTATATCAAACACTTTGCGACA
TGCCGAAGGTACTAAATTGACGATAGATTTATATAATAAAGACGATTATTTACTATTACGTATTCAAGATGATGGTAAAG
GTTTTGATGTAGATGAAAAAATGGAAAAAAGTTATGGATTAAAAAATATGCGAGAACGCGCATTAGAAATCGGAGCAACA
CTGCATATTGTATCATTGCCTGGTGCAGGGACAAGAATTGAAGTGAAAGCGCCGTTGAACAAGGAGGAATTCGATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A143P7E7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	85.591	100	0.856