Detailed information    

insolico Bioinformatically predicted

Overview

Name   comK/comK1   Type   Regulator
Locus tag   I6J75_RS12225 Genome accession   NZ_CP069565
Coordinates   2443602..2444171 (+) Length   189 a.a.
NCBI ID   WP_000287265.1    Uniprot ID   A0A7U7EXU5
Organism   Staphylococcus aureus strain FDAARGOS_1245     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2438602..2449171
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J75_RS12190 (I6J75_12190) - 2439815..2440087 (-) 273 WP_001790097.1 lactococcin 972 family bacteriocin -
  I6J75_RS12195 (I6J75_12195) - 2440097..2440198 (-) 102 WP_001790623.1 hypothetical protein -
  I6J75_RS12200 (I6J75_12200) - 2440744..2440863 (-) 120 WP_020978111.1 hypothetical protein -
  I6J75_RS12205 (I6J75_12205) - 2441115..2441717 (-) 603 WP_001033867.1 CPBP family glutamic-type intramembrane protease -
  I6J75_RS12210 (I6J75_12210) - 2441732..2441908 (-) 177 WP_000214898.1 YkvS family protein -
  I6J75_RS12215 (I6J75_12215) - 2442107..2443093 (+) 987 WP_000668820.1 lipoate--protein ligase -
  I6J75_RS12220 (I6J75_12220) - 2443174..2443392 (-) 219 WP_000876826.1 IDEAL domain-containing protein -
  I6J75_RS12225 (I6J75_12225) comK/comK1 2443602..2444171 (+) 570 WP_000287265.1 competence protein ComK Regulator
  I6J75_RS12240 (I6J75_12240) - 2444658..2446169 (-) 1512 WP_000414177.1 bifunctional UDP-sugar hydrolase/5'-nucleotidase -
  I6J75_RS12245 (I6J75_12245) - 2446308..2447666 (-) 1359 WP_000021864.1 TrkH family potassium uptake protein -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 22601.83 Da        Isoelectric Point: 9.6091

>NTDB_id=535625 I6J75_RS12225 WP_000287265.1 2443602..2444171(+) (comK/comK1) [Staphylococcus aureus strain FDAARGOS_1245]
MYSQNIYVIRKGDMVIRPAFDDDDQRNGSEIIRFDKTRIQNPFKVQKIIERSCKFYGNTYLGKKAETNRITGISSKPPIL
LTPLFPTYFFPTHSDRQNENIWLNMHYIESIKELKNRKCKVTFINNESIILHVSYHSLWHQYNNSIFYYYMVDKQSRMIS
KNPDQPIDYNKATLNVFEALTRYSLFEDK

Nucleotide


Download         Length: 570 bp        

>NTDB_id=535625 I6J75_RS12225 WP_000287265.1 2443602..2444171(+) (comK/comK1) [Staphylococcus aureus strain FDAARGOS_1245]
ATGTATTCTCAAAATATTTATGTGATACGCAAAGGAGACATGGTTATTCGACCAGCATTTGATGATGACGATCAAAGAAA
CGGTAGTGAAATAATTCGGTTTGACAAAACGCGTATTCAAAATCCTTTTAAAGTCCAGAAAATCATTGAACGCTCTTGCA
AATTTTATGGTAATACTTATCTTGGCAAGAAAGCAGAGACAAACCGCATTACTGGCATTTCTAGTAAACCACCTATTTTA
CTAACACCATTATTTCCAACTTATTTTTTCCCAACACATTCTGACAGACAAAATGAAAATATTTGGTTAAATATGCATTA
TATCGAAAGTATTAAAGAATTAAAAAATCGTAAATGTAAAGTGACATTTATTAATAATGAATCAATCATTCTTCATGTTT
CATACCACAGTTTATGGCATCAATATAACAATTCCATTTTTTACTATTACATGGTAGATAAACAATCTCGCATGATATCA
AAAAATCCCGACCAACCAATAGATTATAATAAAGCCACATTGAATGTGTTTGAAGCATTGACACGCTATTCTTTATTTGA
AGATAAATAA

Domains

Predicted by InterproScan.

ComK protein (ComK)

(5-156)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EXU5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comK/comK1 Staphylococcus aureus MW2

100

100

1
  comK/comK1 Staphylococcus aureus N315

100

100

1