Detailed information NTG0535597

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: I6J75_RS03305
• Genome accession: NZ_CP069565
• Coordinates: 705537..706424 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain FDAARGOS_1245
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 700537..711424

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6J75_RS03275 (I6J75_03275)	-	701269..702030 (+)	762	WP_000323455.1	alpha/beta hydrolase family protein	-
I6J75_RS03280 (I6J75_03280)	-	702275..702730 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
I6J75_RS14610	-	702852..702953 (+)	102	WP_000731972.1	SE2200 family small protein	-
I6J75_RS03290 (I6J75_03290)	-	703013..704437 (-)	1425	WP_000953744.1	alkaline phosphatase	-
I6J75_RS03295 (I6J75_03295)	-	704635..704835 (+)	201	WP_000604728.1	hypothetical protein	-
I6J75_RS03300 (I6J75_03300)	braR	704861..705526 (+)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
I6J75_RS03305 (I6J75_03305)	braS	705537..706424 (+)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
I6J75_RS03310 (I6J75_03310)	-	706532..707287 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
I6J75_RS03315 (I6J75_03315)	-	707284..709284 (+)	2001	WP_000776751.1	ABC transporter permease	-
I6J75_RS03320 (I6J75_03320)	-	709943..710056 (+)	114	WP_001791776.1	hypothetical protein	-
I6J75_RS03325 (I6J75_03325)	-	710438..710698 (+)	261	WP_001789910.1	hypothetical protein	-
I6J75_RS03330 (I6J75_03330)	-	710708..711205 (+)	498	WP_001065268.1	glutathione peroxidase	-
I6J75_RS03335 (I6J75_03335)	-	711313..711405 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=535597 I6J75_RS03305 WP_000143419.1 705537..706424(+) (braS) [Staphylococcus aureus strain FDAARGOS_1245]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=535597 I6J75_RS03305 WP_000143419.1 705537..706424(+) (braS) [Staphylococcus aureus strain FDAARGOS_1245]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997