Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   I6J38_RS05380 Genome accession   NZ_CP069558
Coordinates   1085440..1086129 (-) Length   229 a.a.
NCBI ID   WP_020998001.1    Uniprot ID   U2XYT2
Organism   Streptococcus constellatus strain FDAARGOS_1208     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1080440..1091129
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J38_RS05365 (I6J38_05365) nrdR 1081552..1082025 (-) 474 WP_003068126.1 transcriptional regulator NrdR -
  I6J38_RS05370 (I6J38_05370) - 1082208..1083023 (-) 816 WP_020997999.1 endonuclease/exonuclease/phosphatase family protein -
  I6J38_RS05375 (I6J38_05375) - 1083040..1085229 (-) 2190 WP_020998000.1 PTS transporter subunit IIBC -
  I6J38_RS05380 (I6J38_05380) covR 1085440..1086129 (-) 690 WP_020998001.1 response regulator transcription factor Regulator
  I6J38_RS05385 (I6J38_05385) gndA 1086138..1087562 (-) 1425 WP_006268166.1 NADP-dependent phosphogluconate dehydrogenase -
  I6J38_RS05390 (I6J38_05390) - 1087654..1088190 (-) 537 WP_006268073.1 YceD family protein -
  I6J38_RS05395 (I6J38_05395) - 1088378..1089628 (+) 1251 WP_006268318.1 hypothetical protein -
  I6J38_RS05400 (I6J38_05400) htpX 1089697..1090593 (-) 897 WP_006268546.1 zinc metalloprotease HtpX -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26587.66 Da        Isoelectric Point: 6.1345

>NTDB_id=535521 I6J38_RS05380 WP_020998001.1 1085440..1086129(-) (covR) [Streptococcus constellatus strain FDAARGOS_1208]
MGKRILLVENEKKLAQFISLELQNEGYRVDLLETGKDALTSARANQYDLFLLNFMLEDMTGTEFAEQLSLIKPASVIIVL
DNRDIILKYTEEIQRFAVSYMIEPFIVMDLVEKISAIFRGRDFIDHHCSQMKVSTSYRNLRIDVQNHTVYRGNEIISLTR
REYDLLATLMGSHQALSREQLLERVWKYEGAVETNVVDVYIRYLRSKLDIAGQKSYIKTVRGVGYAMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=535521 I6J38_RS05380 WP_020998001.1 1085440..1086129(-) (covR) [Streptococcus constellatus strain FDAARGOS_1208]
ATGGGGAAGCGGATTTTATTAGTTGAGAATGAAAAAAAATTAGCACAATTTATTAGCTTAGAGTTGCAAAATGAAGGTTA
TCGAGTGGATCTTCTTGAAACGGGAAAAGATGCTTTAACATCTGCGAGAGCTAATCAATACGATTTATTCCTGTTGAATT
TTATGCTTGAAGATATGACAGGAACGGAGTTTGCTGAGCAATTAAGTTTGATAAAGCCTGCTTCAGTCATTATTGTATTG
GATAATCGTGATATTATTTTAAAATATACTGAGGAAATCCAACGTTTTGCTGTTAGTTATATGATAGAGCCTTTCATTGT
GATGGACTTGGTCGAAAAAATTTCTGCTATTTTTCGAGGGCGTGATTTTATCGATCATCATTGTAGTCAGATGAAAGTTT
CAACATCTTATCGGAATCTTCGCATTGACGTGCAAAATCATACTGTATATCGAGGGAATGAAATAATTTCTTTGACTAGA
AGAGAGTATGATTTGTTAGCAACGCTGATGGGCAGTCATCAGGCTTTAAGCCGTGAACAGCTGTTAGAGCGCGTTTGGAA
ATACGAAGGAGCAGTCGAAACAAATGTTGTTGATGTCTATATTCGTTATCTTCGTAGTAAACTTGATATAGCAGGGCAGA
AAAGTTACATAAAAACCGTGCGTGGTGTTGGCTATGCTATGCAAGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB U2XYT2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.175

99.563

0.45