Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   I6J37_RS04890 Genome accession   NZ_CP069486
Coordinates   970889..972238 (-) Length   449 a.a.
NCBI ID   WP_103323360.1    Uniprot ID   -
Organism   Mammaliicoccus vitulinus strain FDAARGOS_1207     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 961654..974569 970889..972238 within 0


Gene organization within MGE regions


Location: 961654..974569
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J37_RS04845 (I6J37_04845) - 961663..962445 (+) 783 WP_103322423.1 MBL fold metallo-hydrolase -
  I6J37_RS04850 (I6J37_04850) rlmH 962729..963208 (+) 480 WP_103322420.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  I6J37_RS04855 (I6J37_04855) - 963296..964711 (+) 1416 WP_103322421.1 hypothetical protein -
  I6J37_RS04860 (I6J37_04860) - 964734..965456 (-) 723 WP_103322422.1 DNA-methyltransferase -
  I6J37_RS13340 - 965473..966348 (-) 876 WP_239102456.1 Dam family site-specific DNA-(adenine-N6)-methyltransferase -
  I6J37_RS13345 - 966365..967390 (-) 1026 WP_239102458.1 DNA adenine methylase -
  I6J37_RS04870 (I6J37_04870) - 967493..968005 (-) 513 WP_103323364.1 DUF1643 domain-containing protein -
  I6J37_RS04875 (I6J37_04875) - 968021..968332 (-) 312 WP_103323363.1 DUF960 family protein -
  I6J37_RS04880 (I6J37_04880) - 968428..968766 (-) 339 WP_103323362.1 SAUGI family uracil-DNA glycosylase inhibitor -
  I6J37_RS04885 (I6J37_04885) ccrB 969240..970868 (-) 1629 WP_103323361.1 cassette chromosome recombinase CcrB Machinery gene
  I6J37_RS04890 (I6J37_04890) ccrA 970889..972238 (-) 1350 WP_103323360.1 cassette chromosome recombinase CcrA Machinery gene
  I6J37_RS04895 (I6J37_04895) - 972430..972708 (-) 279 WP_031903869.1 hypothetical protein -
  I6J37_RS04900 (I6J37_04900) cch1 972779..974569 (-) 1791 WP_103323359.1 cassette chromosome replicative helicase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 52317.14 Da        Isoelectric Point: 10.1874

>NTDB_id=535019 I6J37_RS04890 WP_103323360.1 970889..972238(-) (ccrA) [Mammaliicoccus vitulinus strain FDAARGOS_1207]
MKQAMGYLRQSTTKQQSLPAQKQAIKTLAEKHNIQHITFYSDKQSGRTDKRNGYQQITELIQQGRCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKAFDRLKLNIFISLAELESDNIGEQVSNGIKEKARQGKLITTHAPFGYHYK
RGTFTINKNESPTVIAVFNYYLQGNGYKKITQFLEEDNKLLNRKPYQVRNIIMNPNYCGRVINKYGQYDNMFPSIVSTNM
YEQAQALRSQKQIKRTPSDNQLKQKIKCPYCGSTLTNMTIRKKNHALRYYVCSRNMNASHFVCEFKGINAPKLETQVLTT
CQDFFQNQQLYLKINDVIQKRIKKQRALETRSTLTQEQLIDKLAKGAIDAETFRKQSQSLLQQSKPTLSINEQQIQRSFE
NVIQQHFTLSMLYRYIDEIHISKNKSLVGIYFKNEPLNIVNQATQSSIA

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=535019 I6J37_RS04890 WP_103323360.1 970889..972238(-) (ccrA) [Mammaliicoccus vitulinus strain FDAARGOS_1207]
ATGAAACAAGCAATGGGTTACTTACGTCAAAGTACAACAAAACAACAATCACTTCCGGCACAGAAACAAGCCATCAAGAC
ATTAGCTGAAAAACACAATATTCAACACATCACATTTTATAGCGATAAGCAATCAGGACGCACTGATAAGCGAAACGGTT
ACCAGCAAATTACTGAACTGATTCAACAAGGACGATGTGACGTACTATGTTGCTATCGTCTGAATCGACTTCATCGTAAT
CTAAAAAATGCATTAAAACTCATGAAATTGTGCCAAAAATATCATGTTCATATCTTAAGTGTTCATGATGGCTATTTTGA
TATGGATAAAGCATTCGATCGGCTTAAACTTAATATTTTCATCAGCTTGGCCGAATTAGAATCTGATAATATTGGCGAAC
AAGTAAGCAACGGGATAAAAGAAAAAGCGCGTCAGGGTAAATTGATAACTACACACGCCCCCTTTGGTTACCACTACAAA
CGTGGTACATTCACGATAAATAAGAATGAATCACCAACGGTAATTGCCGTATTCAATTACTATCTTCAAGGTAATGGCTA
TAAAAAAATTACACAGTTCTTAGAAGAAGATAACAAACTACTCAACCGGAAACCTTATCAAGTACGTAATATTATTATGA
ATCCCAATTACTGTGGTCGTGTTATCAATAAATATGGACAATATGACAACATGTTTCCGTCTATTGTTTCTACAAATATG
TACGAACAAGCGCAAGCTCTACGATCGCAAAAACAAATCAAACGAACACCTTCAGACAATCAACTCAAACAAAAAATCAA
ATGCCCTTATTGCGGGTCAACCCTTACCAATATGACAATTAGAAAAAAGAACCATGCATTACGTTACTATGTCTGTTCTC
GAAATATGAATGCATCTCATTTTGTCTGTGAATTCAAAGGGATTAATGCGCCAAAACTAGAAACTCAAGTCTTAACTACA
TGTCAGGACTTCTTTCAAAATCAACAACTTTACTTAAAAATCAACGATGTAATTCAAAAACGGATCAAAAAACAAAGGGC
CCTAGAAACTAGGAGCACACTTACACAAGAACAATTGATAGATAAATTAGCTAAAGGAGCCATCGATGCAGAAACGTTCA
GAAAACAATCTCAATCGTTACTTCAACAATCAAAACCAACACTATCAATAAATGAGCAACAAATTCAAAGGTCTTTTGAA
AATGTAATTCAACAACACTTCACGTTAAGCATGTTATACCGATATATTGATGAAATTCATATTTCTAAAAACAAAAGCCT
TGTGGGAATCTATTTCAAAAATGAACCGCTAAACATTGTAAACCAAGCTACGCAATCATCGATTGCTTAA

Domains

Predicted by InterproScan.

Resolvase, N terminal domain (Resolvase)

(4-147)

Recombinase (Recombinase)

(169-250)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-322)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus COL

79.955

100

0.8
  ccrA Staphylococcus aureus N315

75.278

100

0.753