Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   I6J73_RS10250 Genome accession   NZ_CP069473
Coordinates   2165278..2166150 (-) Length   290 a.a.
NCBI ID   WP_002484839.1    Uniprot ID   A0A4Y7VXK4
Organism   Staphylococcus epidermidis strain FDAARGOS_1243     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 2126818..2197692 2165278..2166150 within 0


Gene organization within MGE regions


Location: 2126818..2197692
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J73_RS10105 (I6J73_10105) - 2127858..2129129 (-) 1272 WP_002446308.1 pitrilysin family protein -
  I6J73_RS10110 (I6J73_10110) - 2129159..2129872 (-) 714 WP_002446307.1 GntR family transcriptional regulator -
  I6J73_RS10115 (I6J73_10115) - 2129875..2132268 (-) 2394 WP_002446306.1 DNA translocase FtsK -
  I6J73_RS10120 (I6J73_10120) - 2132535..2134208 (-) 1674 WP_002457357.1 ribonuclease J -
  I6J73_RS10125 (I6J73_10125) pnp 2134576..2136681 (-) 2106 WP_001832554.1 polyribonucleotide nucleotidyltransferase -
  I6J73_RS10130 (I6J73_10130) rpsO 2136813..2137082 (-) 270 WP_002439528.1 30S ribosomal protein S15 -
  I6J73_RS10135 (I6J73_10135) - 2137202..2138173 (-) 972 WP_001832563.1 bifunctional riboflavin kinase/FAD synthetase -
  I6J73_RS10140 (I6J73_10140) truB 2138189..2139106 (-) 918 WP_002439525.1 tRNA pseudouridine(55) synthase TruB -
  I6J73_RS10145 (I6J73_10145) rbfA 2139244..2139594 (-) 351 WP_001829509.1 30S ribosome-binding factor RbfA -
  I6J73_RS10150 (I6J73_10150) infB 2139897..2142059 (-) 2163 WP_002456223.1 translation initiation factor IF-2 -
  I6J73_RS10155 (I6J73_10155) - 2142064..2142381 (-) 318 WP_002439520.1 YlxQ family RNA-binding protein -
  I6J73_RS10160 (I6J73_10160) - 2142381..2142665 (-) 285 WP_001829465.1 YlxR family protein -
  I6J73_RS10165 (I6J73_10165) nusA 2142683..2143906 (-) 1224 WP_001829457.1 transcription termination factor NusA -
  I6J73_RS10170 (I6J73_10170) rimP 2143927..2144394 (-) 468 WP_002439519.1 ribosome maturation factor RimP -
  I6J73_RS10175 (I6J73_10175) - 2144573..2148883 (-) 4311 WP_099833848.1 PolC-type DNA polymerase III -
  I6J73_RS10180 (I6J73_10180) - 2149133..2150836 (-) 1704 WP_001829513.1 proline--tRNA ligase -
  I6J73_RS10185 (I6J73_10185) rseP 2150855..2152141 (-) 1287 WP_001829501.1 RIP metalloprotease RseP -
  I6J73_RS10190 (I6J73_10190) - 2152375..2153157 (-) 783 WP_001829499.1 phosphatidate cytidylyltransferase -
  I6J73_RS10195 (I6J73_10195) - 2153161..2153931 (-) 771 WP_001832561.1 isoprenyl transferase -
  I6J73_RS10200 (I6J73_10200) frr 2154152..2154706 (-) 555 WP_001829472.1 ribosome recycling factor -
  I6J73_RS10205 (I6J73_10205) pyrH 2154723..2155445 (-) 723 WP_002439511.1 UMP kinase -
  I6J73_RS10210 (I6J73_10210) tsf 2155586..2156464 (-) 879 WP_002439509.1 translation elongation factor Ts -
  I6J73_RS10215 (I6J73_10215) rpsB 2156616..2157404 (-) 789 WP_001832557.1 30S ribosomal protein S2 -
  I6J73_RS10220 (I6J73_10220) codY 2157767..2158537 (-) 771 WP_002439506.1 GTP-sensing pleiotropic transcriptional regulator CodY -
  I6J73_RS10225 (I6J73_10225) hslU 2158561..2159964 (-) 1404 WP_001829474.1 ATP-dependent protease ATPase subunit HslU -
  I6J73_RS10230 (I6J73_10230) hslV 2160033..2160575 (-) 543 WP_001829498.1 ATP-dependent protease subunit HslV -
  I6J73_RS10235 (I6J73_10235) xerC 2160579..2161469 (-) 891 WP_002456225.1 tyrosine recombinase XerC -
  I6J73_RS10240 (I6J73_10240) trmFO 2161694..2163001 (-) 1308 WP_001832560.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  I6J73_RS10245 (I6J73_10245) topA 2163026..2165095 (-) 2070 WP_001829508.1 type I DNA topoisomerase -
  I6J73_RS10250 (I6J73_10250) dprA 2165278..2166150 (-) 873 WP_002484839.1 DNA-processing protein DprA Machinery gene
  I6J73_RS12300 - 2166490..2166705 (-) 216 Protein_1983 transposase -
  I6J73_RS10255 (I6J73_10255) sucD 2166955..2167863 (-) 909 WP_002446283.1 succinate--CoA ligase subunit alpha -
  I6J73_RS10260 (I6J73_10260) sucC 2167885..2169051 (-) 1167 WP_002439496.1 ADP-forming succinate--CoA ligase subunit beta -
  I6J73_RS10265 (I6J73_10265) - 2169159..2169929 (-) 771 WP_001829514.1 ribonuclease HII -
  I6J73_RS10270 (I6J73_10270) ylqF 2169934..2170797 (-) 864 WP_002468554.1 ribosome biogenesis GTPase YlqF -
  I6J73_RS10275 (I6J73_10280) - 2171126..2173726 (+) 2601 WP_010959172.1 YfhO family protein -
  I6J73_RS10280 (I6J73_10285) - 2173719..2176322 (+) 2604 WP_020368058.1 YfhO family protein -
  I6J73_RS10285 (I6J73_10290) rplS 2176852..2177202 (-) 351 WP_002436293.1 50S ribosomal protein L19 -
  I6J73_RS10290 (I6J73_10295) trmD 2177308..2178045 (-) 738 WP_049400206.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  I6J73_RS10295 (I6J73_10300) rimM 2178045..2178548 (-) 504 WP_001832559.1 ribosome maturation factor RimM -
  I6J73_RS10300 (I6J73_10305) rpsP 2178675..2178950 (-) 276 WP_002439483.1 30S ribosomal protein S16 -
  I6J73_RS10305 (I6J73_10310) ffh 2179258..2180625 (-) 1368 WP_001830113.1 signal recognition particle protein -
  I6J73_RS10310 (I6J73_10315) - 2180656..2180988 (-) 333 WP_002457379.1 putative DNA-binding protein -
  I6J73_RS10315 (I6J73_10320) ftsY 2180990..2182216 (-) 1227 WP_001830080.1 signal recognition particle-docking protein FtsY -
  I6J73_RS10320 (I6J73_10325) smc 2182213..2185782 (-) 3570 WP_002502436.1 chromosome segregation protein SMC -
  I6J73_RS10325 (I6J73_10330) rnc 2185909..2186646 (-) 738 WP_002470220.1 ribonuclease III -
  I6J73_RS10330 (I6J73_10335) - 2186761..2186994 (-) 234 WP_001830184.1 acyl carrier protein -
  I6J73_RS10335 (I6J73_10340) fabG 2187221..2187955 (-) 735 WP_001830161.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  I6J73_RS10340 (I6J73_10345) fabD 2187948..2188874 (-) 927 WP_001830062.1 ACP S-malonyltransferase -
  I6J73_RS10345 (I6J73_10350) plsX 2188876..2189853 (-) 978 WP_001830112.1 phosphate acyltransferase PlsX -
  I6J73_RS10350 (I6J73_10355) fapR 2189855..2190415 (-) 561 WP_001830099.1 transcription factor FapR -
  I6J73_RS10355 (I6J73_10360) recG 2190574..2192622 (-) 2049 WP_020368084.1 ATP-dependent DNA helicase RecG -
  I6J73_RS10360 (I6J73_10365) fakA 2192826..2194484 (-) 1659 WP_002489351.1 fatty acid kinase catalytic subunit FakA -
  I6J73_RS10365 (I6J73_10370) - 2194499..2194873 (-) 375 WP_001830156.1 Asp23/Gls24 family envelope stress response protein -
  I6J73_RS10370 (I6J73_10375) rpmB 2195231..2195419 (+) 189 WP_001830107.1 50S ribosomal protein L28 -
  I6J73_RS10375 (I6J73_10380) - 2195502..2196137 (-) 636 WP_002489340.1 thiamine diphosphokinase -
  I6J73_RS10380 (I6J73_10385) rpe 2196142..2196786 (-) 645 WP_001830173.1 ribulose-phosphate 3-epimerase -
  I6J73_RS10385 (I6J73_10390) rsgA 2196787..2197662 (-) 876 WP_002456227.1 ribosome small subunit-dependent GTPase A -

Sequence

Protein


Download         Length: 290 a.a.        Molecular weight: 33717.61 Da        Isoelectric Point: 9.3616

>NTDB_id=534959 I6J73_RS10250 WP_002484839.1 2165278..2166150(-) (dprA) [Staphylococcus epidermidis strain FDAARGOS_1243]
MIQQTMLKLYWANFTTAQLHHLTSTYPDFLSENVFHQHDMIKRWLTERNSERLWNKYERFKELKLMDIIKEMKKANVSFT
TYFDDNYPSLCKEMYDYPYVIFYKGNPQFFNHSHSLAVIGSRNATQYTSQSLNYLFPSFRQLNMAIVSGLARGADSVAHQ
TALKYLLPTIGVLGFGHCYHYPKATLNLRTKVERNGLVISEYPPFSPISKHKFPERNRLISGLSRGVLITEAEERSGSQI
TIDCALEQNRNVYVLPGSMFNKMTKGNLRRINEGAQVVIDESSILYDYLF

Nucleotide


Download         Length: 873 bp        

>NTDB_id=534959 I6J73_RS10250 WP_002484839.1 2165278..2166150(-) (dprA) [Staphylococcus epidermidis strain FDAARGOS_1243]
TTGATACAACAGACGATGTTAAAACTATATTGGGCAAATTTCACTACGGCACAACTTCATCATCTTACAAGTACATATCC
TGACTTTCTATCAGAAAACGTATTTCATCAACATGACATGATAAAAAGGTGGCTTACAGAGCGTAATTCTGAAAGGCTAT
GGAACAAATATGAACGTTTCAAAGAATTAAAGCTGATGGACATTATTAAAGAAATGAAAAAAGCAAATGTTAGTTTTACA
ACATACTTTGATGATAACTACCCTTCTCTTTGCAAAGAAATGTATGATTATCCTTATGTGATATTCTACAAAGGAAATCC
ACAGTTCTTTAATCATTCTCACTCTTTAGCTGTAATTGGCTCACGTAATGCCACACAATATACAAGTCAATCTTTAAACT
ATCTTTTTCCTTCATTTAGACAATTAAATATGGCGATTGTTTCTGGATTAGCGCGCGGTGCAGATAGTGTAGCACATCAA
ACCGCACTTAAATACCTATTACCAACTATTGGCGTACTTGGATTTGGCCATTGTTATCATTATCCTAAAGCAACCTTAAA
TTTAAGAACTAAAGTTGAAAGGAATGGCTTAGTGATAAGTGAATATCCACCATTTTCTCCTATAAGTAAGCATAAATTTC
CTGAAAGAAACAGGCTTATAAGTGGTCTGTCCAGAGGGGTACTTATAACTGAGGCTGAAGAAAGAAGTGGTAGTCAAATC
ACTATCGATTGTGCTTTAGAGCAAAATAGAAATGTTTATGTTCTACCTGGTTCAATGTTCAACAAAATGACTAAAGGTAA
TTTAAGAAGGATAAATGAAGGTGCTCAAGTTGTTATAGATGAAAGTAGTATATTATATGATTATCTATTTTAG

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(72-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4Y7VXK4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Staphylococcus aureus MW2

56.944

99.31

0.566
  dprA Staphylococcus aureus N315

56.944

99.31

0.566