Detailed information NTG0534548

Bioinformatically predicted

Overview

• Name: comFA/cflA
• Type: Machinery gene
• Locus tag: JQM34_RS07015
• Genome accession: NZ_CP069427
• Coordinates: 1468009..1469307 (+)
• Length: 432 a.a.
• NCBI ID: WP_200370622.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain SF100
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1463009..1474307

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JQM34_RS06990 (JQM34_0001425)	rpsB	1463834..1464613 (+)	780	WP_000268475.1	30S ribosomal protein S2	-
JQM34_RS06995 (JQM34_0001426)	tsf	1464692..1465732 (+)	1041	WP_000808056.1	translation elongation factor Ts	-
JQM34_RS07000 (JQM34_0001427)	cysK	1465836..1466762 (-)	927	WP_000158480.1	cysteine synthase A	-
JQM34_RS07005 (JQM34_0001428)	-	1466859..1467302 (-)	444	WP_200370619.1	PH domain-containing protein	-
JQM34_RS07010 (JQM34_0001429)	-	1467317..1467952 (-)	636	WP_200370621.1	YigZ family protein	-
JQM34_RS07015 (JQM34_0001430)	comFA/cflA	1468009..1469307 (+)	1299	WP_200370622.1	DEAD/DEAH box helicase	Machinery gene
JQM34_RS07020 (JQM34_0001431)	comFC/cflB	1469304..1469966 (+)	663	WP_200370624.1	ComF family protein	Machinery gene
JQM34_RS07025 (JQM34_0001432)	raiA	1470046..1470594 (+)	549	WP_000599114.1	ribosome-associated translation inhibitor RaiA	-
JQM34_RS07030 (JQM34_0001433)	-	1470676..1471854 (+)	1179	WP_200370626.1	acetyl-CoA C-acetyltransferase	-
JQM34_RS07035 (JQM34_0001434)	-	1472011..1473984 (+)	1974	WP_000739978.1	DHH family phosphoesterase	-

Sequence

Protein

• Length: 432 a.a.
• Molecular weight: 49705.58 Da
• Isoelectric Point: 8.0229

>NTDB_id=534548 JQM34_RS07015 WP_200370622.1 1468009..1469307(+) (comFA/cflA) [Streptococcus oralis strain SF100]
MKVNPNYLGRLFTEKELTEEERQEAVRLPAMRKEKGKLFCQRCNSLILEEWYLPIGAYYCRECLLMKRVRSDQALYYFPQ
EDFPKQDILKWRGQLTPFQEKVSEGLLQAIDKQEPTLVHAVTGAGKTEMIYQVVAKVIDDGGAVCLASPRIDVCLELYKR
LQNDFACDIALLHGESEPYFRTPLVVATTHQLLKFYHAFDLLIVDEVDAFPYVDNTMLYYAVKNSVKEDGLRMFLTATST
DELDRKVRTGELKRLSLPRRFHGNPLIIPKPVWLSDFNRCLEKNQLSTKLKTYIEKQRRTGYPLLIFASEIKKGEKLKEI
LKEQYPNENIGFVSSVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGGRVGRSMDR
PTGELLFFHDGLNASIKKAIKEIKNMNKEAGL

Nucleotide

• Length: 1299 bp

>NTDB_id=534548 JQM34_RS07015 WP_200370622.1 1468009..1469307(+) (comFA/cflA) [Streptococcus oralis strain SF100]
ATGAAAGTAAATCCAAATTATCTCGGTCGCTTGTTTACTGAGAAAGAATTAACGGAAGAAGAACGACAGGAAGCAGTGAG
ACTGCCAGCAATGAGAAAAGAGAAGGGGAAACTGTTTTGTCAACGTTGTAATAGTTTGATTCTAGAAGAATGGTATTTGC
CTATCGGCGCTTACTATTGTAGGGAGTGTTTACTGATGAAGAGAGTCAGGAGTGATCAAGCTTTATACTATTTTCCTCAA
GAGGATTTTCCTAAGCAAGACATCCTCAAATGGCGTGGTCAGTTAACACCTTTTCAAGAAAAAGTGTCAGAGGGACTGCT
TCAAGCAATAGACAAGCAAGAGCCAACCTTGGTTCACGCTGTGACAGGAGCTGGAAAGACAGAGATGATTTATCAAGTTG
TGGCTAAAGTGATTGATGATGGTGGTGCAGTTTGTTTGGCCAGTCCTCGAATTGATGTGTGTTTAGAACTGTATAAGCGA
CTGCAGAATGACTTTGCTTGCGATATAGCGCTACTCCATGGCGAATCAGAGCCCTATTTTCGAACTCCCTTAGTAGTTGC
AACAACTCATCAGTTATTAAAATTTTATCATGCTTTTGATTTGTTGATAGTGGATGAGGTAGATGCCTTTCCTTATGTTG
ACAACACTATGCTTTACTATGCTGTAAAGAATAGTGTAAAGGAGGATGGATTGAGGATGTTCCTTACGGCAACTTCTACA
GATGAGTTAGATAGGAAGGTTCGCACAGGGGAATTAAAAAGATTAAGCTTGCCGAGACGGTTTCATGGAAATCCTTTGAT
TATTCCTAAACCAGTCTGGTTATCGGATTTTAATCGCTGTTTAGAGAAAAATCAATTGTCAACCAAGTTAAAGACTTATA
TTGAGAAACAGAGAAGAACAGGTTATCCCTTACTGATTTTTGCATCAGAGATTAAGAAAGGCGAAAAACTAAAAGAAATC
TTGAAGGAGCAGTACCCGAATGAGAATATCGGCTTTGTGTCTTCTGTGACAGAAGACCGATTAGAGCAGGTGCAAGCTTT
TCGAGATGGAGAACTAACAATACTGATCAGTACGACAATCTTGGAACGCGGGGTTACCTTCCCTTGTGTGGATGTTTTCG
TAGTAGAAGCTAATCATCGTCTCTTTACCAAGTCTAGTTTGATTCAGATTGGAGGGCGAGTTGGACGCAGTATGGACAGA
CCAACTGGTGAGTTGCTCTTCTTTCATGATGGATTAAATGCTTCCATCAAAAAGGCAATCAAGGAAATCAAGAATATGAA
TAAGGAGGCAGGGTTATGA

Domains

Predicted by InterproScan.

• Helicase conserved C-terminal domain (Helicase_C) (292-396)

• Type III restriction enzyme, res subunit (ResIII) (94-166)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comFA/cflA	Streptococcus mitis NCTC 12261	90.741	100	0.907
comFA/cflA	Streptococcus pneumoniae Rx1	90.509	100	0.905
comFA/cflA	Streptococcus pneumoniae D39	90.509	100	0.905
comFA/cflA	Streptococcus pneumoniae R6	90.509	100	0.905
comFA/cflA	Streptococcus pneumoniae TIGR4	90.278	100	0.903
comFA/cflA	Streptococcus mitis SK321	90.046	100	0.9
comFA	Lactococcus lactis subsp. cremoris KW2	51.345	94.676	0.486
comFA	Latilactobacillus sakei subsp. sakei 23K	39.08	100	0.394