Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   JQM34_RS05280 Genome accession   NZ_CP069427
Coordinates   1117565..1118254 (-) Length   229 a.a.
NCBI ID   WP_000518040.1    Uniprot ID   -
Organism   Streptococcus oralis strain SF100     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1112565..1123254
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JQM34_RS05260 (JQM34_0001072) mvaD 1113490..1114443 (-) 954 WP_200370415.1 diphosphomevalonate decarboxylase -
  JQM34_RS05265 (JQM34_0001073) mvk 1114425..1115303 (-) 879 WP_200370417.1 mevalonate kinase -
  JQM34_RS05270 (JQM34_0001074) cbpC 1115421..1116440 (-) 1020 WP_200370418.1 choline-binding protein CbpC -
  JQM34_RS05275 (JQM34_0001075) cbpJ 1116458..1117465 (-) 1008 WP_084860270.1 choline-binding protein CbpJ -
  JQM34_RS05280 (JQM34_0001076) covR 1117565..1118254 (-) 690 WP_000518040.1 response regulator transcription factor Regulator
  JQM34_RS05285 (JQM34_0001077) gndA 1118266..1119690 (-) 1425 WP_000158772.1 NADP-dependent phosphogluconate dehydrogenase -
  JQM34_RS05290 (JQM34_0001078) - 1119766..1121211 (-) 1446 WP_200370419.1 cell division site-positioning protein MapZ family protein -
  JQM34_RS05295 (JQM34_0001079) - 1121224..1122381 (-) 1158 WP_000662905.1 class I SAM-dependent RNA methyltransferase -
  JQM34_RS05305 (JQM34_0001080) gpsB 1122867..1123196 (-) 330 WP_000146523.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26843.00 Da        Isoelectric Point: 8.0271

>NTDB_id=534519 JQM34_RS05280 WP_000518040.1 1117565..1118254(-) (covR) [Streptococcus oralis strain SF100]
MGKRILLLEKERNLSHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNARLGDMTAQDFAERLSRTKPASVIMVL
DHREELQDQIETIQRFAVSYIYKPVIIDQLVARISAIFRGRDFIDQHCSQMKVPTSYRNLRMDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=534519 JQM34_RS05280 WP_000518040.1 1117565..1118254(-) (covR) [Streptococcus oralis strain SF100]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTCTCTCATTTTCTCAGTCTGGAACTCCAAAAAGAGCAATA
CCGTGTTGATCTGGTCGAGGAGGGGCAAAAAGCCCTTTCCATGGCTCTCCAGACAGATTATGACTTGATTTTACTGAATG
CTCGTCTGGGGGATATGACGGCCCAGGATTTTGCAGAGAGGCTGAGTCGGACAAAACCTGCCTCAGTGATCATGGTCTTG
GACCATCGCGAAGAATTGCAAGACCAGATTGAGACAATCCAGCGCTTCGCCGTTTCTTACATCTATAAGCCAGTGATTAT
TGATCAGCTGGTGGCTCGTATTTCAGCGATTTTCCGAGGTCGGGACTTTATCGACCAACATTGTAGTCAGATGAAGGTCC
CAACGTCTTACCGCAATTTGCGTATGGATGTAGAACATCATACCGTTTATCGTGGCGAGGAGATGATTGCTCTGACGCGC
CGTGAGTATGACCTTTTGGCCACTCTCATGGGAAGCAAGAAGGTCTTGACTCGTGAGCAGTTGTTGGAAAGTGTTTGGAA
GTACGAAAGTGCGACAGAAACCAATATCGTGGATGTTTATATCCGTTATCTACGTAGCAAACTTGACGTAAAAGGTCAAA
AGAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAGGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.696

100

0.489
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.491

99.563

0.463