Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   HMPREF1038_RS07605 Genome accession   NC_018630
Coordinates   1429304..1430536 (-) Length   410 a.a.
NCBI ID   WP_000106346.1    Uniprot ID   A0A064C077
Organism   Streptococcus pneumoniae gamPNI0373     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1424304..1435536
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF1038_RS07575 (HMPREF1038_01548) - 1424491..1425459 (+) 969 WP_000081003.1 NAD(P)/FAD-dependent oxidoreductase -
  HMPREF1038_RS07580 (HMPREF1038_01549) whiA 1425493..1426404 (-) 912 WP_000011306.1 DNA-binding protein WhiA -
  HMPREF1038_RS07585 (HMPREF1038_01550) - 1426401..1427378 (-) 978 WP_001231086.1 YvcK family protein -
  HMPREF1038_RS07590 (HMPREF1038_01551) rapZ 1427375..1428265 (-) 891 WP_001844990.1 RNase adapter RapZ -
  HMPREF1038_RS07595 (HMPREF1038_01552) - 1428317..1428697 (-) 381 WP_001140412.1 RidA family protein -
  HMPREF1038_RS07600 (HMPREF1038_01553) yihA 1428708..1429295 (-) 588 WP_000422599.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  HMPREF1038_RS07605 (HMPREF1038_01554) clpX 1429304..1430536 (-) 1233 WP_000106346.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  HMPREF1038_RS07610 (HMPREF1038_01555) - 1430568..1430738 (-) 171 WP_000442275.1 hypothetical protein -
  HMPREF1038_RS07615 (HMPREF1038_01556) - 1430738..1431244 (-) 507 WP_000162486.1 dihydrofolate reductase -
  HMPREF1038_RS07620 (HMPREF1038_01557) - 1431374..1431892 (-) 519 WP_000229874.1 DNA starvation/stationary phase protection protein -
  HMPREF1038_RS07625 (HMPREF1038_01558) lytC 1432388..1433892 (-) 1505 Protein_1459 choline binding-anchored murein hydrolase LytC -
  HMPREF1038_RS07630 (HMPREF1038_01559) tpiA 1433930..1434688 (-) 759 WP_000087897.1 triose-phosphate isomerase -
  HMPREF1038_RS07635 (HMPREF1038_01560) - 1434786..1435463 (-) 678 WP_001844988.1 DnaD domain-containing protein -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45798.35 Da        Isoelectric Point: 4.4550

>NTDB_id=53351 HMPREF1038_RS07605 WP_000106346.1 1429304..1430536(-) (clpX) [Streptococcus pneumoniae gamPNI0373]
MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=53351 HMPREF1038_RS07605 WP_000106346.1 1429304..1430536(-) (clpX) [Streptococcus pneumoniae gamPNI0373]
ATGTCTACAAATAGAAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAACCAAGAAGAAGTACAAAAAATAAT
TGCTGGCAACAATGCTTTTATTTGTAATGAATGCGTGGAGTTAGCTCAGGAAATCATTCGAGAAGAATTGGTTGAGGAAG
TCTTGGCAGACTTGTCTGAGGTGCCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATTGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCGGTTTATAACCACTACAAACGCATCAATTTCCACGATACACGCGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATTTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCCCAGACCTTGGCTA
AGAGCTTGAATGTTCCTTTTGCTATTGCGGATGCGACAGCTCTGACGGAGGCTGGTTATGTGGGTGAGGATGTGGAAAAT
ATCCTCCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTGCCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAACAATAAGGCGATTGACGAAAACAGCTCATACATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACCTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATCGAACGGAAGACAGGGGCGCGTGGGCTTCGCTCCATTATCGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCAAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTCGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A064C077

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.585

100

0.866
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.214

98.049

0.561

Multiple sequence alignment