Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicX   Type   Regulator
Locus tag   HMPREF1038_RS06045 Genome accession   NC_018630
Coordinates   1137256..1138065 (-) Length   269 a.a.
NCBI ID   WP_001289493.1    Uniprot ID   Q9RCS5
Organism   Streptococcus pneumoniae gamPNI0373     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1132256..1143065
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF1038_RS06025 (HMPREF1038_01224) - 1134598..1135584 (+) 987 WP_000204727.1 L-lactate dehydrogenase -
  HMPREF1038_RS06030 (HMPREF1038_01225) - 1135847..1136620 (-) 774 WP_025172523.1 potassium channel family protein -
  HMPREF1038_RS06035 (HMPREF1038_01226) - 1136667..1136921 (-) 255 WP_001823540.1 type II toxin-antitoxin system RelE/ParE family toxin -
  HMPREF1038_RS06040 (HMPREF1038_01227) relB 1136923..1137165 (-) 243 WP_000208080.1 type II toxin-antitoxin system RelB family antitoxin -
  HMPREF1038_RS06045 (HMPREF1038_01228) vicX 1137256..1138065 (-) 810 WP_001289493.1 MBL fold metallo-hydrolase Regulator
  HMPREF1038_RS06050 (HMPREF1038_01229) micB 1138067..1139416 (-) 1350 WP_000886210.1 cell wall metabolism sensor histidine kinase VicK Regulator
  HMPREF1038_RS06055 (HMPREF1038_01230) micA 1139409..1140113 (-) 705 WP_000722076.1 response regulator YycF Regulator
  HMPREF1038_RS06060 (HMPREF1038_01231) mutY 1140168..1141343 (-) 1176 WP_000886147.1 A/G-specific adenine glycosylase -
  HMPREF1038_RS13425 (HMPREF1038_01232) - 1141440..1141565 (+) 126 WP_001818232.1 hypothetical protein -

Sequence

Protein


Download         Length: 269 a.a.        Molecular weight: 29916.89 Da        Isoelectric Point: 6.1743

>NTDB_id=53343 HMPREF1038_RS06045 WP_001289493.1 1137256..1138065(-) (vicX) [Streptococcus pneumoniae gamPNI0373]
MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLLAEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMD
LYANEKTWQAMENSKYLGKVDSSQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKKIYLGHLSKENNIKELAHMTMVN
QLAQADLGVGVDFKVYDTSPDTATPLTEI

Nucleotide


Download         Length: 810 bp        

>NTDB_id=53343 HMPREF1038_RS06045 WP_001289493.1 1137256..1138065(-) (vicX) [Streptococcus pneumoniae gamPNI0373]
ATGAGTGAAATAGGCTTTAAATACAGTATTTTAGCGTCGGGTTCCAGTGGAAATTCTTTTTATCTGGAAACCTCAAAAAA
GAAGCTTTTAGTAGATGCAGGCTTGTCTGGCAAGAAAATTACCAGTCTGCTAGCTGAAATTAACCGTAAGCCAGAAGACC
TGGATGCCATCTTGATTACCCATGAGCATTCAGATCATATCCATGGAGTAGGCGTTTTGGCTCGCAAGTATGGTATGGAT
CTTTATGCCAATGAAAAGACCTGGCAAGCTATGGAAAATAGTAAATATCTTGGCAAGGTGGATTCTTCGCAAAAGCATAT
TTTTGAAATGGGTAAAACCAAAACCTTTGGAGATATCGACATCGAGAGTTTTGGTGTAAGCCATGATGCAGTCGCACCGC
AGTTCTATCGCTTTATGAAGGATGATAAGAGTTTTGTCCTCTTGACAGATACAGGTTATGTCAGTGACCGTATGGCGGGC
ATTGTCGAAAATGCGGATGGTTATCTTATCGAGGCCAACCATGATGTAGAGATTTTGCGATCAGGTTCTTACGCTTGGCG
ACTCAAACAACGAATCCTATCTGACCTTGGTCACCTTTCTAACGAGGACGGTGCTGAAGCTATGATTCGGACGCTAGGAA
ATCGTACTAAGAAGATTTACCTTGGGCATTTATCTAAGGAAAACAATATCAAGGAACTGGCTCATATGACCATGGTCAAT
CAGCTGGCTCAAGCTGATCTGGGAGTCGGAGTAGACTTTAAGGTTTATGATACCTCACCAGATACCGCAACACCATTGAC
AGAGATATAA

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(15-223)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9RCS5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicX Streptococcus mutans UA159

77.323

100

0.773

Multiple sequence alignment