Detailed information    

insolico Bioinformatically predicted

Overview


Name   cipB   Type   Regulator
Locus tag   HMPREF1038_RS02775 Genome accession   NC_018630
Coordinates   512157..512306 (+) Length   49 a.a.
NCBI ID   WP_001809846.1    Uniprot ID   Q00MV6
Organism   Streptococcus pneumoniae gamPNI0373     
Function   indirect induction of ComX; activation of comRS system (predicted from homology)   
Competence regulation

Genomic Context


Location: 507157..517306
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF1038_RS02750 (HMPREF1038_00560) blpC 507421..507576 (-) 156 WP_000358812.1 quorum-sensing system pheromone BlpC -
  HMPREF1038_RS02755 (HMPREF1038_00561) - 507633..508994 (-) 1362 WP_001069064.1 bacteriocin secretion accessory protein -
  HMPREF1038_RS02760 (HMPREF1038_00562) comA/nlmT 509005..511158 (-) 2154 WP_000205159.1 peptide cleavage/export ABC transporter BlpA Regulator
  HMPREF1038_RS02765 (HMPREF1038_00563) blpM 511440..511694 (+) 255 WP_001093255.1 two-peptide bacteriocin subunit BlpM -
  HMPREF1038_RS02770 (HMPREF1038_00564) blpN 511710..511913 (+) 204 WP_001099490.1 two-peptide bacteriocin subunit BlpN -
  HMPREF1038_RS02775 (HMPREF1038_00565) cipB 512157..512306 (+) 150 WP_001809846.1 bacteriocin-like peptide BlpO Regulator
  HMPREF1038_RS02780 (HMPREF1038_00567) - 512410..512529 (+) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  HMPREF1038_RS02795 (HMPREF1038_00569) - 513010..513368 (+) 359 Protein_536 immunity protein -
  HMPREF1038_RS02805 (HMPREF1038_00570) - 513997..514380 (+) 384 WP_000877381.1 hypothetical protein -
  HMPREF1038_RS02810 (HMPREF1038_00571) - 514432..515121 (+) 690 WP_000760532.1 CPBP family intramembrane glutamic endopeptidase -
  HMPREF1038_RS02815 (HMPREF1038_00572) blpZ 515163..515396 (+) 234 WP_000276498.1 immunity protein BlpZ -
  HMPREF1038_RS02820 (HMPREF1038_00573) - 515547..516158 (+) 612 WP_000394044.1 CPBP family intramembrane glutamic endopeptidase -
  HMPREF1038_RS02825 (HMPREF1038_00574) ccrZ 516319..517113 (+) 795 WP_000363002.1 cell cycle regulator CcrZ -

Sequence


Protein


Download         Length: 49 a.a.        Molecular weight: 5149.92 Da        Isoelectric Point: 4.0439

>NTDB_id=53333 HMPREF1038_RS02775 WP_001809846.1 512157..512306(+) (cipB) [Streptococcus pneumoniae gamPNI0373]
MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDGCATTV

Nucleotide


Download         Length: 150 bp        

>NTDB_id=53333 HMPREF1038_RS02775 WP_001809846.1 512157..512306(+) (cipB) [Streptococcus pneumoniae gamPNI0373]
ATGAATACAAAAATGATGTCACAATTTTCTGTTATGGATAATGAAATGCTTGCTTGCGTTGAAGGTGGAGATATTGATTG
GGGAAGAAAAATTAGTTGTGCAGCAGGGGTTGCATATGGCGCAATTGATGGGTGTGCAACAACGGTTTGA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB Q00MV6

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cipB Streptococcus mutans UA159

53.061

100

0.531


Multiple sequence alignment