Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   HMPREF1038_RS02110 Genome accession   NC_018630
Coordinates   379010..379699 (+) Length   229 a.a.
NCBI ID   WP_000518018.1    Uniprot ID   -
Organism   Streptococcus pneumoniae gamPNI0373     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 374010..384699
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF1038_RS02085 (HMPREF1038_00422) gpsB 374119..374448 (+) 330 WP_000146522.1 cell division regulator GpsB -
  HMPREF1038_RS02095 (HMPREF1038_00424) - 374934..376091 (+) 1158 WP_000711391.1 class I SAM-dependent RNA methyltransferase -
  HMPREF1038_RS02100 (HMPREF1038_00425) mapZ 376104..377498 (+) 1395 WP_000039273.1 mid-cell-anchored protein MapZ -
  HMPREF1038_RS02105 (HMPREF1038_00426) gndA 377574..378998 (+) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  HMPREF1038_RS02110 (HMPREF1038_00427) covR 379010..379699 (+) 690 WP_000518018.1 response regulator transcription factor Regulator
  HMPREF1038_RS02115 (HMPREF1038_00428) cbpC 379797..380816 (+) 1020 WP_000771110.1 choline-binding protein CbpC -
  HMPREF1038_RS02120 (HMPREF1038_00429) - 380934..382166 (-) 1233 WP_000765670.1 MFS transporter -
  HMPREF1038_RS02125 (HMPREF1038_00430) - 382326..382796 (-) 471 WP_001844742.1 lanthionine synthetase LanC family protein -
  HMPREF1038_RS13620 - 382696..383034 (-) 339 Protein_406 lanthionine synthetase LanC family protein -
  HMPREF1038_RS02130 (HMPREF1038_00431) - 383904..384026 (+) 123 Protein_407 cell wall-binding protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26898.22 Da        Isoelectric Point: 6.9836

>NTDB_id=53328 HMPREF1038_RS02110 WP_000518018.1 379010..379699(+) (covR) [Streptococcus pneumoniae gamPNI0373]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=53328 HMPREF1038_RS02110 WP_000518018.1 379010..379699(+) (covR) [Streptococcus pneumoniae gamPNI0373]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATGTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATTTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGATATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463

Multiple sequence alignment