Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   C248_RS02990 Genome accession   NC_018608
Coordinates   612104..612673 (+) Length   189 a.a.
NCBI ID   WP_000872879.1    Uniprot ID   A0A2S6DF07
Organism   Staphylococcus aureus 08BA02176     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 607104..617673
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C248_RS02965 (C248_0602) cysE 608316..608963 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  C248_RS02970 (C248_0603) cysS 608947..610347 (+) 1401 WP_000631961.1 cysteine--tRNA ligase -
  C248_RS02975 (C248_0604) - 610340..610744 (+) 405 WP_000370181.1 Mini-ribonuclease 3 -
  C248_RS02980 (C248_0605) rlmB 610752..611498 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  C248_RS02985 (C248_0606) - 611498..612022 (+) 525 WP_000664738.1 NYN domain-containing protein -
  C248_RS02990 (C248_0607) sigH 612104..612673 (+) 570 WP_000872879.1 RNA polymerase sigma factor Regulator
  C248_RS14135 (C248_0608) rpmG 612788..612931 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  C248_RS02995 (C248_0609) secE 612987..613169 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  C248_RS03000 (C248_0610) nusG 613182..613730 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  C248_RS03005 (C248_0612) rplK 613911..614333 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  C248_RS03010 (C248_0613) rplA 614541..615233 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  C248_RS03015 (C248_0614) rplJ 615505..616005 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  C248_RS03020 (C248_0615) rplL 616048..616416 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  C248_RS03025 (C248_0616) - 616591..617199 (+) 609 WP_000020293.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23097.02 Da        Isoelectric Point: 9.7681

>NTDB_id=53192 C248_RS02990 WP_000872879.1 612104..612673(+) (sigH) [Staphylococcus aureus 08BA02176]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGKQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=53192 C248_RS02990 WP_000872879.1 612104..612673(+) (sigH) [Staphylococcus aureus 08BA02176]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAAAGCAGCCTTTCACAAATTATGTTCAGTGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2S6DF07

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979

Multiple sequence alignment