Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   K8Z53_RS22035 Genome accession   NZ_CP083238
Coordinates   4143261..4145357 (+) Length   698 a.a.
NCBI ID   WP_016885804.1    Uniprot ID   -
Organism   Bacillus licheniformis strain 2709     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 4138261..4150357
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K8Z53_RS22010 (K8Z53_21735) queF 4139396..4139893 (-) 498 WP_009328607.1 preQ(1) synthase -
  K8Z53_RS22015 (K8Z53_21740) queE 4139915..4140646 (-) 732 WP_003181103.1 7-carboxy-7-deazaguanine synthase QueE -
  K8Z53_RS22020 (K8Z53_21745) queD 4140639..4141079 (-) 441 WP_003181100.1 6-carboxytetrahydropterin synthase QueD -
  K8Z53_RS22025 (K8Z53_21750) queC 4141082..4141741 (-) 660 WP_003181098.1 7-cyano-7-deazaguanine synthase QueC -
  K8Z53_RS22030 (K8Z53_21755) - 4142006..4143040 (-) 1035 WP_003181096.1 hypothetical protein -
  K8Z53_RS22035 (K8Z53_21760) clpE 4143261..4145357 (+) 2097 WP_016885804.1 ATP-dependent protease ATP-binding subunit ClpE Regulator
  K8Z53_RS22040 (K8Z53_21765) motA 4145556..4146359 (+) 804 WP_003181093.1 flagellar motor stator protein MotA -
  K8Z53_RS22045 (K8Z53_21770) motB 4146352..4147131 (+) 780 WP_003181091.1 flagellar motor protein MotB -
  K8Z53_RS22050 (K8Z53_21775) - 4147156..4147611 (-) 456 WP_003181089.1 MarR family winged helix-turn-helix transcriptional regulator -
  K8Z53_RS22055 (K8Z53_21780) - 4147849..4149360 (+) 1512 WP_003181087.1 PAS domain-containing sensor histidine kinase -
  K8Z53_RS22060 (K8Z53_21785) - 4149422..4149664 (-) 243 WP_003181085.1 aspartyl-phosphate phosphatase Spo0E family protein -
  K8Z53_RS22065 (K8Z53_21790) - 4149883..4150212 (+) 330 WP_011197892.1 YkvA family protein -

Sequence

Protein


Download         Length: 698 a.a.        Molecular weight: 78062.17 Da        Isoelectric Point: 5.5477

>NTDB_id=531269 K8Z53_RS22035 WP_016885804.1 4143261..4145357(+) (clpE) [Bacillus licheniformis strain 2709]
MRCQHCQKNEATIRLNMQINFTKKQMDLCEDCYKELTQPSMFSGNHFFGGGGSFFSQPSQAQTQTAAKKGLLDELAVNLT
NAAKTGLIDPVIGRDDEVARVIEILNRRNKNNPVLIGEPGVGKTAVAEGLALKIAEGDVPNKLKNKELYLLDVASLVANT
GIRGQFEERMKQLMKELKERKNAILFIDEIHLLVGAGSAEGSMDAGNILKPALARGELQVIGATTLKEYRQIEKDAALER
RFQPIMVHEPTIEQAAAILNGLKEKYEAYHDVTYSDEAIKACVILSSRYIQDRHLPDKAIDLLDEAGSKANLKIDTVSGE
QASQRLQEIEAEKAKALQEENYELAAKLRDEEEALHKKMESHEEEKRATVEAEDIQAIIEQKTGIPVGKLQHDDQKKMKE
LEANLSSRVIGQKEAVKKVAKAVRRSRAGLKSKNRPVGSFLFVGPTGVGKTELSKRLAEELFGTKDAIIRLDMSEYMEKH
AVSKLIGSPPGYVGHEEAGQLTEKVRRNPYSIVLLDEIEKAHPDVQHMFLQIMEDGRLTDSQGRTVSFKDTVIIMTSNAG
VSEKRTTVGFNREEQVMGEQSMIDSLSGYFKPEFLNRFDSIIEFQPLEKEDLVKIAALLLKELEETLKEQNMTLEVSDEA
KEKIAEIGYHPAFGARPLRRTIQTAVEDQMTDLLLEEEHIKGFAVIVENDEIRVKTTR

Nucleotide


Download         Length: 2097 bp        

>NTDB_id=531269 K8Z53_RS22035 WP_016885804.1 4143261..4145357(+) (clpE) [Bacillus licheniformis strain 2709]
ATGCGTTGTCAACATTGTCAAAAAAATGAGGCGACGATTCGCCTAAACATGCAAATCAACTTTACAAAAAAACAAATGGA
TTTATGTGAAGACTGCTATAAAGAGCTGACTCAGCCTTCTATGTTTTCAGGAAATCACTTTTTTGGCGGCGGAGGTTCTT
TCTTCAGCCAGCCATCACAAGCGCAGACGCAAACCGCTGCCAAAAAAGGCTTGCTCGATGAACTTGCCGTCAATTTAACA
AATGCAGCAAAGACCGGCTTGATCGATCCGGTGATCGGCCGCGATGATGAAGTAGCCCGTGTGATCGAGATCTTAAACCG
CAGAAATAAAAACAATCCGGTCTTAATCGGTGAACCGGGCGTCGGTAAAACAGCCGTCGCTGAAGGACTTGCTCTCAAAA
TCGCCGAAGGCGATGTTCCAAATAAATTGAAAAACAAAGAGCTCTACCTGCTTGATGTCGCTTCCCTCGTGGCAAACACC
GGCATCAGAGGGCAATTTGAAGAAAGAATGAAACAGCTGATGAAAGAGCTGAAAGAACGCAAAAACGCAATCTTGTTTAT
TGACGAAATTCACCTTCTTGTCGGGGCCGGCTCTGCAGAAGGCTCCATGGATGCGGGCAACATTTTAAAACCTGCACTTG
CCAGAGGCGAGCTGCAAGTTATCGGCGCTACGACGTTGAAGGAATATCGCCAAATTGAAAAAGATGCGGCGTTAGAGCGG
CGCTTCCAGCCGATCATGGTGCACGAACCGACAATTGAGCAGGCCGCAGCGATTTTAAACGGTCTCAAGGAAAAATACGA
AGCATATCACGATGTGACTTACTCGGATGAAGCGATCAAAGCCTGCGTCATTCTGTCAAGCCGCTATATTCAGGACCGCC
ATCTTCCCGATAAGGCGATTGACCTTTTGGATGAAGCCGGTTCAAAAGCGAACTTGAAAATCGACACGGTCAGCGGTGAA
CAAGCTTCCCAACGCCTGCAAGAAATCGAAGCGGAAAAAGCCAAAGCGCTTCAAGAAGAAAACTACGAGCTTGCAGCAAA
ACTCCGCGACGAAGAAGAAGCGCTGCATAAAAAAATGGAAAGCCATGAGGAAGAAAAACGGGCAACAGTTGAAGCGGAAG
ACATTCAAGCGATCATCGAACAAAAAACCGGCATTCCGGTCGGCAAGCTTCAGCACGACGATCAGAAGAAAATGAAAGAG
CTTGAAGCAAACCTTTCAAGCCGCGTGATCGGTCAAAAAGAAGCGGTGAAAAAAGTGGCAAAAGCCGTCAGAAGAAGCCG
CGCCGGCCTGAAATCAAAAAACAGGCCTGTCGGTTCATTCCTGTTCGTCGGCCCGACAGGTGTCGGTAAAACAGAACTTT
CTAAAAGGCTTGCGGAAGAACTGTTCGGCACGAAGGATGCCATCATCCGCCTCGATATGAGCGAATACATGGAAAAACAC
GCCGTATCAAAGCTGATCGGTTCACCTCCTGGATATGTCGGCCACGAAGAAGCCGGACAGCTTACCGAAAAAGTCCGGAG
GAACCCGTACAGCATCGTTTTGCTCGATGAAATCGAAAAAGCCCATCCCGATGTCCAGCACATGTTCCTGCAAATCATGG
AAGACGGACGTCTGACAGACAGCCAAGGGCGGACGGTCAGCTTTAAAGATACCGTCATTATTATGACAAGCAATGCCGGT
GTATCTGAAAAGCGGACAACCGTCGGTTTTAACCGGGAAGAGCAAGTAATGGGCGAACAATCAATGATCGATTCATTAAG
CGGCTACTTTAAGCCGGAATTCCTGAACAGATTTGACAGCATCATCGAATTCCAGCCGCTCGAAAAAGAAGATCTGGTCA
AGATCGCCGCCCTCTTGCTGAAAGAGCTTGAAGAAACGTTAAAAGAGCAAAACATGACGCTCGAAGTTTCAGATGAGGCA
AAAGAAAAAATCGCTGAAATCGGATACCATCCGGCCTTTGGCGCCCGCCCATTAAGAAGAACCATTCAAACAGCGGTCGA
AGATCAAATGACCGATCTGCTGCTTGAAGAAGAACACATCAAAGGTTTTGCGGTTATCGTTGAAAACGATGAAATCCGGG
TGAAAACAACCAGATAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(607-682)

ATPase family associated with various cellular activities (AAA) (AAA)

(114-245)

AAA lid domain (AAA_lid_9)

(252-350)

AAA domain (Cdc48 subfamily) (AAA_2)

(435-601)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

56.15

100

0.602
  clpE Streptococcus pneumoniae TIGR4

55.481

100

0.595
  clpE Streptococcus pneumoniae Rx1

55.481

100

0.595
  clpE Streptococcus pneumoniae D39

55.481

100

0.595
  clpE Streptococcus pneumoniae R6

55.481

100

0.595
  clpC Lactococcus lactis subsp. cremoris KW2

55.45

100

0.583
  clpC Bacillus subtilis subsp. subtilis str. 168

53.765

95.129

0.511
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

47.52

89.542

0.426
  clpC Streptococcus thermophilus LMD-9

46.226

91.117

0.421
  clpC Streptococcus thermophilus LMG 18311

46.215

90.831

0.42
  clpC Streptococcus pneumoniae D39

46.87

89.255

0.418
  clpC Streptococcus pneumoniae TIGR4

46.87

89.255

0.418
  clpC Streptococcus pneumoniae Rx1

46.87

89.255

0.418
  clpC Streptococcus mutans UA159

47.078

88.252

0.415
  clpA Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

42.998

86.963

0.374