Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   JMB28_RS05245 Genome accession   NZ_CP068712
Coordinates   1122172..1122801 (+) Length   209 a.a.
NCBI ID   WP_017723494.1    Uniprot ID   -
Organism   Staphylococcus shinii strain 14AME19     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1117172..1127801
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JMB28_RS05220 (JMB28_05220) - 1118015..1119004 (-) 990 WP_039069014.1 aromatic acid exporter family protein -
  JMB28_RS05225 (JMB28_05225) map 1119181..1119933 (+) 753 WP_039069016.1 type I methionyl aminopeptidase -
  JMB28_RS05230 (JMB28_05230) - 1120038..1120424 (+) 387 WP_039069017.1 hypothetical protein -
  JMB28_RS05235 (JMB28_05235) liaF 1120441..1121142 (+) 702 WP_202847927.1 cell wall-active antibiotics response protein LiaF -
  JMB28_RS05240 (JMB28_05240) vraS 1121139..1122182 (+) 1044 WP_069792526.1 sensor histidine kinase Regulator
  JMB28_RS05245 (JMB28_05245) vraR 1122172..1122801 (+) 630 WP_017723494.1 response regulator transcription factor Regulator
  JMB28_RS05250 (JMB28_05250) - 1122937..1124094 (-) 1158 WP_039069020.1 YihY/virulence factor BrkB family protein -
  JMB28_RS05255 (JMB28_05255) - 1124446..1124730 (-) 285 WP_069792527.1 hypothetical protein -
  JMB28_RS05260 (JMB28_05260) - 1124737..1125201 (-) 465 WP_039069024.1 low molecular weight protein-tyrosine-phosphatase -
  JMB28_RS05265 (JMB28_05265) - 1125336..1125539 (+) 204 WP_039069025.1 DUF1128 family protein -
  JMB28_RS05270 (JMB28_05270) - 1125557..1126795 (+) 1239 WP_069792528.1 aminopeptidase -
  JMB28_RS05275 (JMB28_05275) - 1126888..1127409 (+) 522 WP_039069028.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23734.27 Da        Isoelectric Point: 4.7778

>NTDB_id=530599 JMB28_RS05245 WP_017723494.1 1122172..1122801(+) (vraR) [Staphylococcus shinii strain 14AME19]
MPIKVLFVDDHEMVRIGISSYLSTQPDIDVVGEGKSGKEAIEKAHQLNPDLILMDLLMDDMDGVEATEQVKKDLPHMKVV
MLTSYIEDNEVYRALDSGVDSYILKTTSASDIAEAIRKTYNNESVFEAEVLVKMRNRMKQRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=530599 JMB28_RS05245 WP_017723494.1 1122172..1122801(+) (vraR) [Staphylococcus shinii strain 14AME19]
ATGCCGATTAAAGTTTTATTTGTGGATGATCATGAAATGGTCCGAATTGGAATATCTAGCTATTTATCAACACAACCAGA
TATTGATGTTGTAGGAGAAGGGAAGTCCGGAAAGGAAGCAATTGAAAAGGCACACCAATTGAATCCAGATTTAATATTAA
TGGATTTATTAATGGATGATATGGACGGTGTTGAAGCAACCGAACAAGTGAAAAAAGATTTACCTCATATGAAAGTAGTC
ATGCTTACAAGTTATATAGAAGATAACGAAGTATATCGTGCGCTTGATTCAGGAGTGGATAGTTATATTTTAAAAACAAC
AAGCGCTAGTGATATTGCAGAAGCAATCAGAAAAACCTATAATAATGAGTCGGTTTTTGAAGCGGAAGTTTTAGTTAAGA
TGAGAAATAGGATGAAACAACGCGCAGAATTATATGAAATGCTAACAGAGCGTGAGATGGAAATATTATTGTTAATTGCA
AAAGGCTATTCAAACCAAGAAATTGCAAGTGCTTCACATATTACAATTAAAACGGTTAAAACACATGTAAGTAATATTTT
AAGTAAATTAGAAGTGCAAGATAGAACGCAAGCTGTTATTTACGCTTTTCAACATAACTTAATTCAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-117)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

88.517

100

0.885
  degU Bacillus subtilis subsp. subtilis str. 168

34.375

100

0.368