Detailed information NTG0528479

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: JG554_RS04760
• Genome accession: NZ_CP068241
• Coordinates: 1025162..1026205 (+)
• Length: 347 a.a.
• NCBI ID: WP_046207953.1
• Uniprot ID: A0A9Q2L749
• Organism: Staphylococcus sp. 11-B-312
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1020162..1031205

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JG554_RS04735 (JG554_04735)	-	1021232..1021957 (+)	726	WP_064209718.1	glutamine amidotransferase	-
JG554_RS04740 (JG554_04740)	-	1022042..1023028 (-)	987	WP_064209717.1	aromatic acid exporter family protein	-
JG554_RS04745 (JG554_04745)	map	1023204..1023956 (+)	753	WP_046207955.1	type I methionyl aminopeptidase	-
JG554_RS04750 (JG554_04750)	-	1024061..1024447 (+)	387	WP_019469613.1	hypothetical protein	-
JG554_RS04755 (JG554_04755)	liaF	1024464..1025165 (+)	702	WP_064209716.1	cell wall-active antibiotics response protein LiaF	-
JG554_RS04760 (JG554_04760)	vraS	1025162..1026205 (+)	1044	WP_046207953.1	sensor histidine kinase	Regulator
JG554_RS04765 (JG554_04765)	vraR	1026195..1026824 (+)	630	WP_019469616.1	response regulator transcription factor	Regulator
JG554_RS04770 (JG554_04770)	-	1026894..1027982 (-)	1089	WP_046207952.1	YihY/virulence factor BrkB family protein	-
JG554_RS04775 (JG554_04775)	-	1028286..1028570 (-)	285	WP_203265379.1	YtxH domain-containing protein	-
JG554_RS04780 (JG554_04780)	-	1028578..1029042 (-)	465	WP_046207950.1	low molecular weight protein-tyrosine-phosphatase	-
JG554_RS04785 (JG554_04785)	-	1029175..1029378 (+)	204	WP_046207949.1	DUF1128 family protein	-
JG554_RS04790 (JG554_04790)	-	1029393..1030631 (+)	1239	WP_064209715.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39974.35 Da
• Isoelectric Point: 5.8518

>NTDB_id=528479 JG554_RS04760 WP_046207953.1 1025162..1026205(+) (vraS) [Staphylococcus sp. 11-B-312]
MNHYIRAIGSMLILVYSTFFAMFFIDKVFVNIIYFQGMIYTQIFGIPVLLFINLLVILLCIIVGSVLAYKINQQNHWLQD
QIERSIEGQTVGINDQNIELYNETIELYQTLVPLNQEVHKLRLKTQNLTNESYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETDLKAPLDQQIPVLEKMVQDSQLEMRALLLHLRPIGLKDKSLGQGIKDLVVDLQKKVPMKVVHDI
EDFDVPKGIEDHLFRITQEAISNTLRHSKGTKVTIELFNREEYLLLRIQDDGKGFNVDDKVEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYAD

Nucleotide

• Length: 1044 bp

>NTDB_id=528479 JG554_RS04760 WP_046207953.1 1025162..1026205(+) (vraS) [Staphylococcus sp. 11-B-312]
ATGAATCACTACATAAGAGCAATAGGGTCGATGTTGATATTAGTTTATAGTACATTTTTCGCTATGTTTTTTATAGATAA
AGTATTTGTGAATATTATATATTTTCAAGGTATGATTTATACACAAATCTTTGGTATTCCAGTTTTACTATTTATTAATT
TATTAGTTATATTACTATGCATCATAGTTGGCTCAGTATTAGCATATAAAATCAACCAACAAAATCATTGGTTACAAGAT
CAAATTGAACGTTCTATTGAAGGACAAACAGTTGGTATCAACGACCAGAATATAGAATTATATAATGAAACAATTGAATT
ATATCAGACACTTGTACCGCTCAATCAAGAAGTTCATAAATTACGTTTAAAAACACAAAATTTAACGAATGAATCATATA
ATATGAACGATGTGAAAGTTAAAAAAATAATTGAAGATGAAAGGCAAAGACTGGCTCGTGAGTTACATGATTCCGTTAGC
CAGCAACTATTTGCAGCAAGCATGATGCTCTCTGCCATTAAAGAAACTGATTTGAAAGCACCTTTAGATCAACAAATTCC
AGTATTGGAAAAAATGGTCCAAGATTCACAATTAGAAATGCGTGCCTTGCTATTACATTTAAGACCAATTGGCTTGAAGG
ATAAATCACTTGGCCAAGGTATCAAAGATTTAGTAGTTGATCTACAGAAAAAAGTGCCAATGAAAGTCGTACATGATATT
GAGGATTTCGACGTTCCTAAAGGCATTGAAGATCATTTGTTTAGAATTACACAAGAAGCAATTTCAAATACATTAAGACA
TTCAAAAGGTACAAAAGTTACAATTGAATTGTTTAATAGAGAAGAATATTTATTATTACGTATACAAGATGATGGTAAAG
GCTTTAACGTTGATGATAAGGTAGAACAAAGCTATGGGTTAAAAAATATGCGTGAACGAGCACTTGAAATTGGCGCAACA
TTTCATATAGTATCACTGCCAGATTCAGGAACACGGATTGAAGTTAAAGCCCCATTAAATAAGGAGGATTCGTATGCCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	87.32	100	0.873