Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   JHW37_RS24390 Genome accession   NZ_CP068238
Coordinates   5200056..5201393 (+) Length   445 a.a.
NCBI ID   WP_033999343.1    Uniprot ID   -
Organism   Pseudomonas aeruginosa strain A39-1     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 5195056..5206393
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JHW37_RS24365 (JHW37_24365) pgeF 5195201..5195929 (-) 729 WP_053817769.1 peptidoglycan editing factor PgeF -
  JHW37_RS24370 (JHW37_24370) rluD 5195926..5196888 (-) 963 WP_003150035.1 23S rRNA pseudouridine(1911/1915/1917) synthase RluD -
  JHW37_RS24375 (JHW37_24375) - 5197034..5198059 (+) 1026 WP_012077305.1 outer membrane protein assembly factor BamD -
  JHW37_RS24380 (JHW37_24380) - 5198213..5198458 (+) 246 WP_003150030.1 PP0621 family protein -
  JHW37_RS24385 (JHW37_24385) pilS 5198448..5200040 (+) 1593 WP_053817770.1 two-component system sensor histidine kinase PilS Regulator
  JHW37_RS24390 (JHW37_24390) pilR 5200056..5201393 (+) 1338 WP_033999343.1 two-component system response regulator PilR Regulator
  JHW37_RS24395 (JHW37_24395) thiO 5201439..5202533 (-) 1095 WP_033999365.1 glycine oxidase ThiO -
  JHW37_RS24400 (JHW37_24400) - 5202668..5203177 (+) 510 WP_003150026.1 GspH/FimT family protein -
  JHW37_RS24405 (JHW37_24405) - 5203283..5203789 (+) 507 WP_012077308.1 Tfp pilus assembly protein FimT/FimU -
  JHW37_RS24410 (JHW37_24410) pilV 5203780..5204337 (+) 558 WP_034081446.1 type IV pilus modification protein PilV Machinery gene
  JHW37_RS24415 (JHW37_24415) pilW 5204334..5205158 (+) 825 WP_034081447.1 type 4a pilus minor pilin PilW -
  JHW37_RS24420 (JHW37_24420) pilX 5205155..5205742 (+) 588 WP_034081449.1 type 4a pilus minor pilin PilX -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 49762.11 Da        Isoelectric Point: 6.1219

>NTDB_id=528427 JHW37_RS24390 WP_033999343.1 5200056..5201393(+) (pilR) [Pseudomonas aeruginosa strain A39-1]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPTELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MPMQVKLLRAIQEKAVRAVGGQQEIGVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCENDQIQPHDLRLADAPGASQDGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=528427 JHW37_RS24390 WP_033999343.1 5200056..5201393(+) (pilR) [Pseudomonas aeruginosa strain A39-1]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAGCTGCTGGAAATCACCCTCGGCCGCATGAA
GCTGGATACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAACCGTTCGACCTGTGCCTGACCG
ACATGCGCCTGCCGGACGGTAGCGGCCTCGACCTGGTGCAGTACATCCAGCAGCGTCACCCGCAGACCCCGGTCGCCATG
ATCACCGCCTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGCGCCTTCGACTTCCTCACCAAGCCGGTCGA
CCTCGGCCGCCTGCGCGAACTGGTGGCGACCGCCCTGCGCCTGCGCAATCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCGCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGCGGCGAGTCCGGCAGCGGCAAGGAACTGGTGGCCCGCCTGATCCACGAGCAGGGGCCGCGCATCGAGCGACCGTT
CGTGCCGGTCAACTGCGGCGCGATCCCTACCGAGCTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACCG
GCGCCATCGAGGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGTACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGCCGATGCAGGTCAAGCTGCTCCGCGCAATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGATCGGCGT
CGACGTCCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAGGTCGGCGCCGGGCGCTTCCGCCAGGATCTCTACT
ACCGCCTCAACGTCATCGAATTGCGCGTTCCGCCCCTGCGCGAACGCCGCGAGGACATCCCGCTGCTGGCCGAGCGCATC
CTCAAACGCCTGGCCGGCGATACCGGCTTGCCGGCCGCCCGCCTGACCGGCGATGCCCAGGAAAAGCTGAAGAACTATCG
CTTCCCCGGCAACGTGCGTGAACTGGAGAACATGCTGGAGCGCGCCTACACGCTGTGCGAGAACGACCAGATCCAGCCCC
ACGACCTGCGCCTGGCCGACGCGCCGGGTGCCAGCCAGGACGGCGCGGCAAGCCTGAGCGAGATAGACAATCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCTCTCGAGGAGACCCGCTGGAACCGCACTGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGTTCGATGCGTTATCGCCTGAAGAAACTCGGCATAGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(7-115)

Sigma-54 interaction domain (Sigma54_activat)

(135-301)

Bacterial regulatory protein, Fis family (HTH_8)

(402-442)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

98.652

100

0.987
  pilR Acinetobacter baumannii strain A118

51.416

100

0.53
  luxO Vibrio cholerae strain A1552

38.063

99.775

0.38