Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   I6J13_RS09235 Genome accession   NZ_CP068213
Coordinates   1875572..1876627 (+) Length   351 a.a.
NCBI ID   WP_003070174.1    Uniprot ID   -
Organism   Streptococcus constellatus strain FDAARGOS_1156     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1870572..1881627
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J13_RS09205 (I6J13_09205) - 1871091..1871726 (-) 636 WP_006269864.1 YigZ family protein -
  I6J13_RS09210 (I6J13_09210) comFA/cflA 1871783..1873084 (+) 1302 WP_037565799.1 DEAD/DEAH box helicase Machinery gene
  I6J13_RS09215 (I6J13_09215) - 1873081..1873746 (+) 666 WP_003043136.1 ComF family protein -
  I6J13_RS09220 (I6J13_09220) hpf 1873825..1874367 (+) 543 WP_003032381.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  I6J13_RS09225 (I6J13_09225) rsmD 1874565..1875104 (+) 540 WP_037565796.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  I6J13_RS09230 (I6J13_09230) coaD 1875094..1875591 (+) 498 WP_003070176.1 pantetheine-phosphate adenylyltransferase -
  I6J13_RS09235 (I6J13_09235) sepM 1875572..1876627 (+) 1056 WP_003070174.1 SepM family pheromone-processing serine protease Regulator
  I6J13_RS09240 (I6J13_09240) - 1876914..1877471 (+) 558 WP_003070172.1 YutD family protein -
  I6J13_RS09245 (I6J13_09245) rlmN 1877505..1878587 (+) 1083 WP_006269861.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  I6J13_RS09250 (I6J13_09250) - 1878580..1879098 (+) 519 WP_003070167.1 VanZ family protein -
  I6J13_RS09255 (I6J13_09255) cclA/cilC 1879093..1879767 (-) 675 WP_003070165.1 A24 family peptidase Machinery gene
  I6J13_RS09260 (I6J13_09260) - 1879918..1880445 (+) 528 WP_003070162.1 DNA starvation/stationary phase protection protein -
  I6J13_RS09265 (I6J13_09265) - 1880710..1880934 (+) 225 WP_003070161.1 YqgQ family protein -
  I6J13_RS09270 (I6J13_09270) - 1880928..1881308 (+) 381 WP_003070160.1 rhodanese-like domain-containing protein -

Sequence

Protein


Download         Length: 351 a.a.        Molecular weight: 38285.34 Da        Isoelectric Point: 10.2305

>NTDB_id=528077 I6J13_RS09235 WP_003070174.1 1875572..1876627(+) (sepM) [Streptococcus constellatus strain FDAARGOS_1156]
MEKSRTKFKKWPIVAVVGLLLLFMSFIVPLPYYIEVPGGAADVRQVLRVDNKVDKEKGSYNFVTVGIQHATFAHLVYAWL
TPFTDIYSAKDLTGGTSDKEYMRINQFYMETSQNLAKYQGLKKAGKDISLKYLGVYVLQVTKNSTFKGILNIADTVTGVN
DKTFNSSKDLIDYVGSQKIGSKVKVNYVEDGQKKSAIGKIIKLENGKNGIGISLIDRTEVASNIPIEFSTAGIGGPSAGL
MFSLAIYTQIADPTLRDGRNIAGTGSIDREGKVGDIGGIDKKVVSAAKNGAEIFFAPNNPVTKEVKKSNPKAKTNYETAL
AAAKKIKTKMKIVPVKTLQDAIDYLKSTKKS

Nucleotide


Download         Length: 1056 bp        

>NTDB_id=528077 I6J13_RS09235 WP_003070174.1 1875572..1876627(+) (sepM) [Streptococcus constellatus strain FDAARGOS_1156]
ATGGAAAAATCACGAACTAAATTTAAAAAATGGCCGATAGTGGCTGTAGTAGGGCTGCTTCTACTGTTCATGTCTTTTAT
AGTTCCTCTGCCTTATTACATTGAGGTGCCAGGTGGTGCAGCAGATGTTCGGCAAGTATTACGTGTAGATAATAAAGTGG
ATAAGGAAAAAGGTTCTTATAACTTTGTCACTGTTGGGATTCAGCATGCAACCTTTGCTCATTTGGTTTATGCTTGGTTG
ACTCCTTTTACAGATATTTATTCGGCGAAAGATCTGACTGGCGGAACTTCTGATAAAGAATATATGCGAATCAATCAATT
TTATATGGAAACATCACAAAACTTAGCCAAATATCAAGGTTTGAAAAAAGCGGGCAAGGATATTAGCTTGAAATATTTGG
GTGTTTATGTGTTGCAAGTTACCAAGAATTCAACCTTTAAAGGGATTCTAAATATTGCAGATACTGTGACAGGCGTGAAT
GATAAGACTTTCAACAGTTCAAAAGATTTGATTGATTATGTAGGCTCACAGAAAATTGGCAGCAAGGTCAAGGTGAACTA
TGTAGAAGACGGTCAGAAAAAATCTGCTATAGGTAAAATTATCAAACTTGAAAATGGAAAAAATGGAATTGGTATTAGCT
TAATTGACCGAACAGAAGTCGCAAGTAATATACCAATTGAATTTTCAACAGCGGGGATTGGTGGACCAAGTGCGGGCTTG
ATGTTTAGCTTGGCGATTTATACACAGATTGCAGACCCGACATTGAGAGATGGCAGAAATATTGCTGGGACAGGATCGAT
TGACCGTGAAGGAAAAGTTGGTGATATTGGTGGGATTGATAAAAAAGTTGTTTCAGCAGCTAAAAATGGCGCAGAAATTT
TCTTTGCGCCAAATAATCCAGTCACCAAGGAAGTGAAAAAATCCAATCCTAAAGCGAAAACAAACTATGAGACAGCTTTG
GCAGCTGCTAAAAAAATTAAAACTAAAATGAAAATTGTACCTGTCAAGACCTTGCAAGACGCAATTGATTACCTCAAAAG
TACTAAAAAATCTTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(133-195)

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(234-307)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

63.372

98.006

0.621