Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   I6J13_RS04650 Genome accession   NZ_CP068213
Coordinates   969036..969725 (-) Length   229 a.a.
NCBI ID   WP_006269448.1    Uniprot ID   A0AAD2SXA0
Organism   Streptococcus constellatus strain FDAARGOS_1156     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 964036..974725
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J13_RS04630 (I6J13_04630) nrdR 964597..965070 (-) 474 WP_006269445.1 transcriptional regulator NrdR -
  I6J13_RS04635 (I6J13_04635) - 965269..965757 (+) 489 WP_006269443.1 hypothetical protein -
  I6J13_RS04640 (I6J13_04640) - 965804..966619 (-) 816 WP_006269465.1 endonuclease/exonuclease/phosphatase family protein -
  I6J13_RS04645 (I6J13_04645) - 966636..968825 (-) 2190 WP_037565534.1 PTS transporter subunit IIBC -
  I6J13_RS04650 (I6J13_04650) covR 969036..969725 (-) 690 WP_006269448.1 response regulator transcription factor Regulator
  I6J13_RS04655 (I6J13_04655) gndA 969734..971158 (-) 1425 WP_006269467.1 NADP-dependent phosphogluconate dehydrogenase -
  I6J13_RS04660 (I6J13_04660) - 971363..972028 (+) 666 WP_006269469.1 TetR/AcrR family transcriptional regulator -
  I6J13_RS04665 (I6J13_04665) - 972018..972752 (+) 735 WP_003029928.1 ABC transporter ATP-binding protein -
  I6J13_RS04670 (I6J13_04670) - 972736..973464 (+) 729 WP_006269451.1 ABC transporter permease -
  I6J13_RS04675 (I6J13_04675) - 973464..973691 (+) 228 WP_003029926.1 hypothetical protein -
  I6J13_RS04680 (I6J13_04680) - 973958..974497 (-) 540 WP_006270463.1 DUF177 domain-containing protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26545.64 Da        Isoelectric Point: 6.1329

>NTDB_id=528034 I6J13_RS04650 WP_006269448.1 969036..969725(-) (covR) [Streptococcus constellatus strain FDAARGOS_1156]
MGKRILLVENEKKLAQFICLELQNEGYRVDLLETGKDALASARANQYDLFLLNFMLEDMTGTEFAEQLSLIKPASVIIVL
DNRDIILKYTEEIQRFAVSYMIEPFIAMDLVEKISAIFRGRDFIDHHCSQMKVSTSYRNLRIDVQNHTVYRGNEIISLTR
REYDLLATLMGSHQALSREQLLERVWKYEGAVETNVVDVYIRYLRSKLDIAGQKSYIKTVRGVGYAMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=528034 I6J13_RS04650 WP_006269448.1 969036..969725(-) (covR) [Streptococcus constellatus strain FDAARGOS_1156]
ATGGGGAAGCGGATTTTATTAGTTGAGAATGAAAAAAAATTAGCACAATTTATTTGCTTAGAGTTGCAAAATGAAGGTTA
TCGAGTGGATCTTCTTGAAACGGGAAAAGATGCTTTAGCATCTGCGAGAGCTAATCAATACGATTTATTCCTGTTGAATT
TTATGCTTGAAGATATGACAGGAACGGAGTTTGCTGAGCAATTAAGTTTGATAAAGCCTGCTTCAGTCATTATTGTATTG
GATAATCGTGATATTATTTTAAAATATACTGAGGAAATCCAACGTTTTGCTGTTAGTTATATGATAGAGCCTTTCATTGC
GATGGACTTGGTCGAAAAAATTTCTGCTATTTTTCGTGGGCGTGATTTTATTGATCATCATTGTAGTCAGATGAAAGTTT
CAACATCTTATCGGAATCTTCGCATTGACGTGCAAAATCATACTGTATATCGAGGGAATGAAATAATTTCCTTGACTAGA
AGAGAGTATGATTTGTTAGCAACGCTGATGGGCAGTCATCAGGCTTTAAGCCGTGAACAGCTGTTAGAGCGCGTTTGGAA
ATACGAAGGAGCAGTTGAAACAAATGTTGTTGATGTCTATATTCGTTATCTTCGTAGTAAACTTGATATAGCAGGGCAGA
AAAGTTACATAAAAACCGTGCGTGGTGTTGGCTATGCTATGCAAGAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-227)

Response regulator receiver domain (Response_reg)

(5-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.737

99.563

0.445