Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   K6969_RS09410 Genome accession   NZ_CP082205
Coordinates   1954759..1955400 (-) Length   213 a.a.
NCBI ID   WP_002937025.1    Uniprot ID   A0A0H3MTV8
Organism   Streptococcus suis strain AKJ18     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1949759..1960400
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6969_RS09385 (K6969_09280) comFA/cflA 1949913..1951205 (-) 1293 WP_171943154.1 DEAD/DEAH box helicase Machinery gene
  K6969_RS09390 (K6969_09285) - 1951262..1951894 (+) 633 WP_029173961.1 YigZ family protein -
  K6969_RS09395 (K6969_09290) cysK 1951983..1952909 (+) 927 WP_029173960.1 cysteine synthase A -
  K6969_RS09400 (K6969_09295) - 1952936..1953307 (-) 372 WP_029173959.1 S1 RNA-binding domain-containing protein -
  K6969_RS09405 (K6969_09300) - 1953309..1954709 (-) 1401 WP_029173958.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  K6969_RS09410 (K6969_09305) vraR 1954759..1955400 (-) 642 WP_002937025.1 response regulator transcription factor Regulator
  K6969_RS09415 (K6969_09310) - 1955372..1956388 (-) 1017 WP_014637529.1 sensor histidine kinase -
  K6969_RS09420 (K6969_09315) liaF 1956385..1957044 (-) 660 WP_228377879.1 cell wall-active antibiotics response protein LiaF -
  K6969_RS09425 (K6969_09320) - 1957776..1958897 (-) 1122 WP_015445098.1 IS110 family transposase -
  K6969_RS09430 (K6969_09325) - 1959402..1959734 (+) 333 Protein_1836 IS110 family transposase -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23790.36 Da        Isoelectric Point: 4.8970

>NTDB_id=527372 K6969_RS09410 WP_002937025.1 1954759..1955400(-) (vraR) [Streptococcus suis strain AKJ18]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAKALEVKPDVVVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILAAIRKVALGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=527372 K6969_RS09410 WP_002937025.1 1954759..1955400(-) (vraR) [Streptococcus suis strain AKJ18]
ATGAATACGATTCGAGTGATGTTGGTTGACGACCATGAGATGGTTCGTCTAGGATTGAAAAGTTACTTAAATTTACAGCC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAAGGTTTGGCTAAAGCATTAGAGGTTAAACCTGATGTTGTAG
TGATGGACTTGGTTATGCCCAAGATGACTGGCGTAGAAGCAACTCTGGCCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACCTCCTATCTAGATAATGAAAAAATCTATCCTGTGCTGGAAGCAGGAGCTCGTGGCTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGCAGCTATCCGCAAGGTAGCTCTTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACTTGACAGCTCGTGAACGCGAAATCTTGACGCTGTTAGCC
AAGGGATATGATAATCAACGAATTGCAGATGAGTCTTTCATTTCCCTAAAAACTGTTAAGACCCATGTTTCCAATATCTT
ATCTAAACTAGCTGTTAGCGATCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGAGGATCAAT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MTV8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.589

97.183

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.938

100

0.413