Detailed information NTG0526978

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: I6J04_RS10930
• Genome accession: NZ_CP068079
• Coordinates: 2232040..2233083 (+)
• Length: 347 a.a.
• NCBI ID: WP_015900704.1
• Uniprot ID: A0AAJ0JP10
• Organism: Staphylococcus carnosus strain FDAARGOS_1147
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2227040..2238083

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6J04_RS10905 (I6J04_10905)	-	2228017..2228742 (+)	726	WP_046100409.1	type 1 glutamine amidotransferase	-
I6J04_RS10910 (I6J04_10910)	-	2228792..2229778 (-)	987	WP_046100410.1	FUSC family protein	-
I6J04_RS10915 (I6J04_10915)	map	2230030..2230797 (+)	768	WP_015900707.1	type I methionyl aminopeptidase	-
I6J04_RS10920 (I6J04_10920)	-	2230931..2231326 (+)	396	WP_015900706.1	hypothetical protein	-
I6J04_RS10925 (I6J04_10925)	liaF	2231342..2232043 (+)	702	WP_046100411.1	cell wall-active antibiotics response protein LiaF	-
I6J04_RS10930 (I6J04_10930)	vraS	2232040..2233083 (+)	1044	WP_015900704.1	sensor histidine kinase	Regulator
I6J04_RS10935 (I6J04_10935)	vraR	2233073..2233702 (+)	630	WP_046100412.1	response regulator transcription factor	Regulator
I6J04_RS10940 (I6J04_10940)	-	2233752..2234330 (-)	579	WP_015900702.1	beta-class carbonic anhydrase	-
I6J04_RS10945 (I6J04_10945)	-	2234540..2235616 (-)	1077	WP_046100413.1	YihY/virulence factor BrkB family protein	-
I6J04_RS10950 (I6J04_10950)	-	2235735..2236031 (-)	297	WP_015900700.1	hypothetical protein	-
I6J04_RS10955 (I6J04_10955)	-	2236039..2236503 (-)	465	WP_046100414.1	low molecular weight protein-tyrosine-phosphatase	-
I6J04_RS10960 (I6J04_10960)	-	2236739..2236945 (+)	207	WP_015900698.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40122.55 Da
• Isoelectric Point: 5.1667

>NTDB_id=526978 I6J04_RS10930 WP_015900704.1 2232040..2233083(+) (vraS) [Staphylococcus carnosus strain FDAARGOS_1147]
MNHYIRAIGSMLILIYSILAIFFFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNIIVILMSIIVGSVLAYKVNQQNHWIKD
QIEHSIEGEVVGINDQHIELYQETLDIYHMLVPLNQELHRLRIKTQDLTNETYNLNDTKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPTLEKMIQDSQLEMRALLLHLRPLGLKDRSLGEGIKDLVVDLQKKVPMKVVYDI
EDFEVPKGIEDHLFRITQEGISNTLRHAEGSKLTIDLYNKDDYLLLRIQDDGKGFDVDEKMEKSYGLKNMRERALEIGAT
LHIVSLPGAGTRIEVKAPLNKEEFDDD

Nucleotide

• Length: 1044 bp

>NTDB_id=526978 I6J04_RS10930 WP_015900704.1 2232040..2233083(+) (vraS) [Staphylococcus carnosus strain FDAARGOS_1147]
ATGAACCATTATATAAGAGCTATAGGTTCAATGTTAATACTGATTTACAGTATTTTAGCCATATTCTTTTTCATTGATAA
AGTCTTTGTAAATATTATCTTTTTTCAAGGAATGTTCTATACACAAATTTTTGGGATTCCGGTATTTTTGTTTTTAAATA
TCATTGTGATACTTATGTCTATTATCGTAGGTTCTGTTTTAGCATATAAGGTCAACCAGCAAAACCACTGGATTAAAGAT
CAAATTGAACATTCAATTGAAGGTGAAGTAGTTGGAATAAATGATCAACATATCGAACTTTATCAAGAAACACTCGATAT
TTACCATATGCTAGTACCTTTAAACCAAGAATTACATCGCTTACGTATCAAGACACAAGATTTAACGAATGAAACTTATA
ATTTGAATGATACAAAAGTGAAGAAAATTATAGAAGATGAACGTCAGCGTTTGGCCAGAGAATTGCATGACTCAGTCAGT
CAGCAATTATTTGCTGCGAGTATGATGTTATCTGCTATTAAAGAAACGAAGTTAGAACCGCCTTTAGATCAGCAAATTCC
AACACTTGAAAAAATGATTCAAGATTCACAACTTGAAATGCGTGCTTTATTACTCCATTTGCGTCCGTTAGGCTTGAAGG
ATCGCTCATTAGGAGAAGGTATTAAAGACTTGGTTGTGGACTTGCAGAAAAAAGTGCCGATGAAAGTAGTATATGACATC
GAAGATTTTGAAGTACCAAAAGGGATTGAAGATCATTTATTTCGTATTACCCAAGAAGGTATTTCAAATACGCTAAGACA
TGCTGAAGGTTCAAAATTAACAATAGATTTATATAATAAAGACGATTACTTACTTTTACGTATTCAAGATGATGGTAAAG
GTTTTGATGTAGATGAAAAAATGGAAAAAAGTTATGGATTAAAAAATATGCGAGAACGCGCATTAGAAATCGGAGCAACA
CTGCATATTGTATCATTGCCTGGTGCAGGGACAAGAATTGAAGTGAAAGCGCCGTTGAACAAGGAGGAATTCGATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	84.726	100	0.847