Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   I6J04_RS10615 Genome accession   NZ_CP068079
Coordinates   2167825..2168541 (-) Length   238 a.a.
NCBI ID   WP_046100375.1    Uniprot ID   -
Organism   Staphylococcus carnosus strain FDAARGOS_1147     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2162825..2173541
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J04_RS10595 (I6J04_10595) - 2164064..2164708 (+) 645 WP_046100371.1 redox-sensing transcriptional repressor Rex -
  I6J04_RS10600 (I6J04_10600) - 2164758..2164982 (-) 225 WP_046100372.1 sulfurtransferase TusA family protein -
  I6J04_RS10605 (I6J04_10605) - 2165009..2166094 (-) 1086 WP_046100373.1 YeeE/YedE family protein -
  I6J04_RS10610 (I6J04_10610) - 2166306..2167778 (+) 1473 WP_046100374.1 GH32 C-terminal domain-containing protein -
  I6J04_RS10615 (I6J04_10615) agrA 2167825..2168541 (-) 717 WP_046100375.1 quorum-sensing response regulator AgrA Regulator
  I6J04_RS10620 (I6J04_10620) agrC 2168546..2169841 (-) 1296 WP_046100376.1 quorum-sensing sensor histidine kinase AgrC -
  I6J04_RS10625 (I6J04_10625) agrD 2169873..2170010 (-) 138 WP_015900791.1 cyclic lactone autoinducer peptide AgrD -
  I6J04_RS10630 (I6J04_10630) - 2170147..2170593 (-) 447 WP_308669865.1 accessory gene regulator AgrB -
  I6J04_RS13835 (I6J04_10635) - 2171091..2171171 (+) 81 WP_041612998.1 delta-lysin family phenol-soluble modulin -
  I6J04_RS10640 (I6J04_10640) - 2171484..2172284 (-) 801 WP_046100377.1 carbon-nitrogen family hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27873.74 Da        Isoelectric Point: 4.9636

>NTDB_id=526977 I6J04_RS10615 WP_046100375.1 2167825..2168541(-) (agrA) [Staphylococcus carnosus strain FDAARGOS_1147]
MKIIICEDDQQQRAHIEEIINNYIMIEEKPLEIALSTNDPYEVIEYAKNTNDICCYFLDIQLDADINGIKLGSELRKFDT
VGNIVFVTSHSELTYLTFVYKVAAMDFIFKDDPSEMKSRIIDCIETALTRLQLLSKESNVETIELKRGSNSVYVNYDDVM
FFESSTKSHRLIAHLDNRQIEFYGSLKELSNIDERFFRCHKSFVINRNNIEEVISKEREIHFKNGEHCYVSVRNLKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=526977 I6J04_RS10615 WP_046100375.1 2167825..2168541(-) (agrA) [Staphylococcus carnosus strain FDAARGOS_1147]
ATGAAAATTATTATTTGTGAAGACGACCAGCAACAACGCGCACATATCGAAGAAATTATCAATAACTATATAATGATTGA
AGAAAAGCCATTAGAAATTGCTCTCTCAACTAATGATCCATATGAAGTAATTGAATACGCTAAAAATACAAATGACATTT
GTTGTTACTTCTTAGATATTCAACTTGACGCAGATATAAATGGGATTAAACTCGGTAGTGAGTTACGTAAATTTGATACG
GTTGGGAATATTGTTTTTGTGACAAGTCATAGCGAATTGACTTACTTAACTTTTGTTTATAAAGTAGCAGCAATGGATTT
TATCTTTAAAGATGATCCTAGCGAAATGAAATCACGGATTATTGATTGCATTGAAACAGCACTTACACGTTTGCAGCTAT
TATCTAAAGAAAGCAACGTTGAAACAATCGAACTTAAAAGAGGCAGTAATTCTGTCTATGTTAATTACGATGATGTAATG
TTTTTCGAATCATCCACTAAATCTCATAGATTGATTGCACATTTAGATAATCGTCAAATTGAGTTTTATGGAAGTTTGAA
AGAACTCAGTAATATTGATGAACGCTTCTTCCGTTGTCACAAAAGCTTTGTAATCAACCGCAATAATATCGAAGAAGTGA
TTTCAAAAGAACGTGAAATTCACTTTAAAAACGGCGAACATTGCTATGTCTCTGTCCGTAACCTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

78.992

100

0.79
  comE Streptococcus mitis NCTC 12261

34.263

100

0.361