Detailed information
Bioinformatically predicted
Overview
| Name | ccrA | Type | Machinery gene |
| Locus tag | I6J07_RS11490 | Genome accession | NZ_CP068063 |
| Coordinates | 2292800..2294149 (-) | Length | 449 a.a. |
| NCBI ID | WP_103170149.1 | Uniprot ID | - |
| Organism | Staphylococcus equorum strain FDAARGOS_1150 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 2240587..2294149 | 2292800..2294149 | within | 0 |
Gene organization within MGE regions
Location: 2240587..2294149
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| I6J07_RS11210 (I6J07_11225) | ccrC | 2240587..2242263 (+) | 1677 | WP_103170548.1 | cassette chromosome recombinase CcrC | - |
| I6J07_RS11215 (I6J07_11230) | - | 2242369..2242707 (+) | 339 | WP_103170549.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| I6J07_RS11220 (I6J07_11235) | - | 2242803..2243114 (+) | 312 | WP_103170550.1 | DUF960 family protein | - |
| I6J07_RS11225 (I6J07_11240) | - | 2243133..2243672 (+) | 540 | WP_103170551.1 | DUF1643 domain-containing protein | - |
| I6J07_RS11230 (I6J07_11245) | - | 2243718..2244044 (+) | 327 | WP_103170552.1 | hypothetical protein | - |
| I6J07_RS11235 (I6J07_11250) | - | 2244053..2244300 (+) | 248 | Protein_2173 | DUF4870 domain-containing protein | - |
| I6J07_RS11240 (I6J07_11255) | - | 2244346..2244705 (-) | 360 | Protein_2174 | type I restriction enzyme endonuclease domain-containing protein | - |
| I6J07_RS11245 (I6J07_11260) | - | 2244854..2245537 (+) | 684 | WP_103170553.1 | Wzz/FepE/Etk N-terminal domain-containing protein | - |
| I6J07_RS11250 (I6J07_11265) | - | 2245537..2246223 (+) | 687 | WP_103170554.1 | polysaccharide biosynthesis tyrosine autokinase | - |
| I6J07_RS11255 (I6J07_11270) | - | 2246223..2246987 (+) | 765 | WP_103170555.1 | tyrosine-protein phosphatase | - |
| I6J07_RS11260 (I6J07_11275) | - | 2247010..2248824 (+) | 1815 | WP_103170556.1 | polysaccharide biosynthesis protein | - |
| I6J07_RS11265 (I6J07_11280) | - | 2248814..2250007 (+) | 1194 | WP_103170557.1 | hypothetical protein | - |
| I6J07_RS11270 (I6J07_11285) | - | 2250000..2251250 (+) | 1251 | WP_103170558.1 | hypothetical protein | - |
| I6J07_RS11275 (I6J07_11290) | - | 2251282..2252283 (+) | 1002 | WP_103170559.1 | NAD-dependent epimerase | - |
| I6J07_RS11280 (I6J07_11295) | - | 2252304..2253578 (+) | 1275 | WP_103170560.1 | nucleotide sugar dehydrogenase | - |
| I6J07_RS11285 (I6J07_11300) | - | 2253632..2254759 (+) | 1128 | WP_103170561.1 | glycosyltransferase family 4 protein | - |
| I6J07_RS11290 (I6J07_11305) | - | 2254856..2255449 (+) | 594 | WP_103170562.1 | sugar transferase | - |
| I6J07_RS11295 (I6J07_11310) | - | 2255446..2256060 (+) | 615 | WP_103170563.1 | acetyltransferase | - |
| I6J07_RS11300 (I6J07_11315) | - | 2256067..2257197 (+) | 1131 | WP_276307632.1 | DegT/DnrJ/EryC1/StrS family aminotransferase | - |
| I6J07_RS11305 (I6J07_11320) | - | 2257222..2258160 (+) | 939 | WP_103170564.1 | LCP family protein | - |
| I6J07_RS11310 (I6J07_11325) | - | 2258377..2259336 (+) | 960 | WP_040762886.1 | IS30 family transposase | - |
| I6J07_RS11315 (I6J07_11330) | - | 2259636..2260241 (+) | 606 | Protein_2189 | N-acyl homoserine lactonase family protein | - |
| I6J07_RS11320 (I6J07_11335) | - | 2260620..2261465 (+) | 846 | WP_103170506.1 | hypothetical protein | - |
| I6J07_RS13820 | - | 2261576..2262286 (+) | 711 | WP_103170505.1 | helix-turn-helix domain-containing protein | - |
| I6J07_RS11335 (I6J07_11350) | - | 2262316..2264328 (+) | 2013 | WP_201650502.1 | hypothetical protein | - |
| I6J07_RS11340 (I6J07_11355) | - | 2264498..2265607 (+) | 1110 | WP_103170357.1 | DNA polymerase | - |
| I6J07_RS11345 (I6J07_11360) | - | 2265600..2265968 (+) | 369 | WP_002511800.1 | hypothetical protein | - |
| I6J07_RS11350 (I6J07_11365) | - | 2265968..2267584 (+) | 1617 | WP_201650505.1 | DUF5906 domain-containing protein | - |
| I6J07_RS11355 (I6J07_11370) | ccrC | 2267809..2269491 (+) | 1683 | WP_201650508.1 | cassette chromosome recombinase CcrC | - |
| I6J07_RS11360 (I6J07_11375) | - | 2269590..2269940 (+) | 351 | WP_056936155.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| I6J07_RS11365 (I6J07_11380) | - | 2270025..2270336 (+) | 312 | WP_103170500.1 | DUF960 family protein | - |
| I6J07_RS11370 (I6J07_11385) | - | 2270352..2270858 (+) | 507 | WP_069820765.1 | DUF1643 domain-containing protein | - |
| I6J07_RS11375 (I6J07_11390) | - | 2270975..2271340 (+) | 366 | WP_069820766.1 | DUF4870 domain-containing protein | - |
| I6J07_RS13970 | - | 2271447..2271590 (+) | 144 | Protein_2201 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| I6J07_RS11385 (I6J07_11400) | - | 2271804..2272367 (+) | 564 | WP_069820767.1 | hypothetical protein | - |
| I6J07_RS13825 | - | 2272428..2272931 (+) | 504 | WP_236582928.1 | hypothetical protein | - |
| I6J07_RS11395 (I6J07_11410) | galU | 2273228..2274091 (+) | 864 | WP_276307630.1 | UTP--glucose-1-phosphate uridylyltransferase GalU | - |
| I6J07_RS11400 (I6J07_11415) | - | 2274350..2275471 (+) | 1122 | WP_103170498.1 | glycosyltransferase family 2 protein | - |
| I6J07_RS11405 (I6J07_11420) | - | 2275471..2277498 (+) | 2028 | WP_201650512.1 | CDP-glycerol glycerophosphotransferase family protein | - |
| I6J07_RS11410 (I6J07_11425) | - | 2277508..2277915 (+) | 408 | WP_201650513.1 | hypothetical protein | - |
| I6J07_RS11415 (I6J07_11430) | - | 2278182..2279333 (+) | 1152 | WP_103170547.1 | DUF6270 domain-containing protein | - |
| I6J07_RS11420 (I6J07_11435) | - | 2279364..2280680 (+) | 1317 | WP_201650516.1 | glycosyltransferase family 2 protein | - |
| I6J07_RS13830 | - | 2281000..2282337 (+) | 1338 | WP_226908943.1 | hypothetical protein | - |
| I6J07_RS11430 (I6J07_11445) | fadH | 2282527..2283291 (+) | 765 | WP_053464979.1 | 2,4-dienoyl-CoA reductase | - |
| I6J07_RS11435 (I6J07_11450) | nadA | 2283518..2284618 (-) | 1101 | WP_053464978.1 | quinolinate synthase NadA | - |
| I6J07_RS11440 (I6J07_11455) | nadC | 2284619..2285452 (-) | 834 | WP_053464977.1 | carboxylating nicotinate-nucleotide diphosphorylase | - |
| I6J07_RS11445 (I6J07_11460) | - | 2285403..2286977 (-) | 1575 | WP_053464976.1 | L-aspartate oxidase | - |
| I6J07_RS11450 (I6J07_11465) | - | 2287065..2288156 (+) | 1092 | WP_053464975.1 | cysteine desulfurase family protein | - |
| I6J07_RS11455 (I6J07_11470) | - | 2288158..2288697 (+) | 540 | WP_053464974.1 | transcription repressor NadR | - |
| I6J07_RS11460 (I6J07_11475) | - | 2288646..2289032 (-) | 387 | Protein_2217 | type I restriction-modification system subunit M N-terminal domain-containing protein | - |
| I6J07_RS11465 (I6J07_11480) | - | 2289175..2289396 (-) | 222 | WP_103170153.1 | hypothetical protein | - |
| I6J07_RS11470 (I6J07_11485) | - | 2289411..2289917 (-) | 507 | WP_031797623.1 | DUF1643 domain-containing protein | - |
| I6J07_RS11475 (I6J07_11490) | - | 2289931..2290242 (-) | 312 | WP_103170152.1 | DUF960 family protein | - |
| I6J07_RS11480 (I6J07_11495) | - | 2290338..2290676 (-) | 339 | WP_103170151.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| I6J07_RS11485 (I6J07_11500) | ccrB | 2291151..2292779 (-) | 1629 | WP_103170150.1 | cassette chromosome recombinase CcrB | Machinery gene |
| I6J07_RS11490 (I6J07_11505) | ccrA | 2292800..2294149 (-) | 1350 | WP_103170149.1 | cassette chromosome recombinase CcrA | Machinery gene |
Sequence
Protein
Download Length: 449 a.a. Molecular weight: 52158.98 Da Isoelectric Point: 10.1127
>NTDB_id=526892 I6J07_RS11490 WP_103170149.1 2292800..2294149(-) (ccrA) [Staphylococcus equorum strain FDAARGOS_1150]
MKQAMGYLRQSTTKQQSLPAQKQAIKTLAEKHNIQHITFYSDKQSARTDKRNGYQQITELIQQGQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKAFDRLKLNIFISLAELESDNIGEQVKNGIKEKAKQGKMITTHAPFGYQYH
NGTFTIDTVKAPTIKAVFSYYLQGYGYKKIAQYLEADEKFINRKPYQVRNIIMNPNYCGRVINQYGQYDNMCPSIVSTSI
YEQAQAIRSQKQLKRTSSANQLKQKIKCPYCGSTLTNITIRKKHRTLRYYVCPQNMNASRFVCEFKGINAQSLEASVLAT
CQDFFQNQHLYSKINHTIQKRLKKQKDIEAKSTVTQEQLIEKLAQGKIDAETFREQTQSFRQQSKPITSIHTHQIQKALQ
NVIQQRFTLNMLYPYIDEIHITRNKILTGIYFKNEPLNIVNQTAQSSIA
MKQAMGYLRQSTTKQQSLPAQKQAIKTLAEKHNIQHITFYSDKQSARTDKRNGYQQITELIQQGQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKAFDRLKLNIFISLAELESDNIGEQVKNGIKEKAKQGKMITTHAPFGYQYH
NGTFTIDTVKAPTIKAVFSYYLQGYGYKKIAQYLEADEKFINRKPYQVRNIIMNPNYCGRVINQYGQYDNMCPSIVSTSI
YEQAQAIRSQKQLKRTSSANQLKQKIKCPYCGSTLTNITIRKKHRTLRYYVCPQNMNASRFVCEFKGINAQSLEASVLAT
CQDFFQNQHLYSKINHTIQKRLKKQKDIEAKSTVTQEQLIEKLAQGKIDAETFREQTQSFRQQSKPITSIHTHQIQKALQ
NVIQQRFTLNMLYPYIDEIHITRNKILTGIYFKNEPLNIVNQTAQSSIA
Nucleotide
Download Length: 1350 bp
>NTDB_id=526892 I6J07_RS11490 WP_103170149.1 2292800..2294149(-) (ccrA) [Staphylococcus equorum strain FDAARGOS_1150]
ATGAAACAAGCAATGGGTTACTTACGTCAAAGTACAACAAAACAACAATCACTTCCGGCACAGAAACAAGCGATCAAGAC
ATTAGCTGAAAAACACAATATTCAACACATCACATTTTATAGCGATAAGCAATCAGCACGCACTGATAAGCGAAACGGTT
ACCAGCAAATTACTGAACTGATTCAACAAGGACAATGTGACGTACTATGTTGCTATCGTCTGAATCGACTTCATCGTAAT
CTAAAAAATGCATTAAAACTCATGAAATTATGTCAAAAATACCATGTTCATATTCTAAGTGTTCATGATGGCTATTTTGA
TATGGATAAAGCATTCGATCGGCTCAAACTCAATATTTTCATCAGCTTGGCCGAACTAGAATCCGATAATATAGGCGAAC
AAGTCAAAAATGGAATCAAAGAAAAAGCGAAACAAGGTAAAATGATTACAACACATGCACCCTTTGGGTATCAATATCAT
AATGGTACTTTCACGATAGACACAGTAAAAGCACCAACAATAAAAGCTGTATTCAGTTATTATCTTCAAGGCTATGGTTA
TAAAAAAATTGCACAGTACTTAGAAGCTGACGAGAAATTCATCAATCGTAAACCCTATCAAGTACGTAATATTATCATGA
ACCCCAATTATTGTGGTCGAGTCATTAATCAATACGGGCAATATGACAACATGTGTCCTTCTATTGTTTCGACAAGTATA
TATGAACAAGCTCAAGCGATACGATCACAAAAGCAACTCAAACGGACATCATCAGCTAATCAACTCAAACAAAAAATCAA
ATGTCCTTATTGTGGTTCAACGTTGACTAATATAACCATTAGAAAAAAGCACCGTACATTACGTTATTATGTCTGTCCAC
AAAATATGAATGCATCTCGTTTTGTCTGTGAATTCAAAGGAATCAACGCACAATCATTAGAAGCGAGTGTCTTAGCTACA
TGTCAAGATTTCTTTCAAAATCAACATCTGTATTCAAAAATCAACCATACAATCCAAAAACGACTCAAAAAACAAAAAGA
CATAGAAGCTAAAAGTACAGTCACGCAAGAACAACTGATAGAAAAATTAGCCCAAGGTAAAATTGATGCAGAAACATTCA
GAGAACAAACGCAATCATTTCGACAACAGTCAAAACCTATAACATCAATCCATACGCATCAAATTCAAAAGGCTTTACAA
AATGTCATTCAACAACGTTTCACATTAAACATGTTGTACCCTTACATTGATGAAATTCATATTACCAGAAATAAAATACT
TACGGGTATCTATTTCAAAAATGAACCCTTAAACATCGTCAATCAAACAGCACAATCATCGATTGCTTAA
ATGAAACAAGCAATGGGTTACTTACGTCAAAGTACAACAAAACAACAATCACTTCCGGCACAGAAACAAGCGATCAAGAC
ATTAGCTGAAAAACACAATATTCAACACATCACATTTTATAGCGATAAGCAATCAGCACGCACTGATAAGCGAAACGGTT
ACCAGCAAATTACTGAACTGATTCAACAAGGACAATGTGACGTACTATGTTGCTATCGTCTGAATCGACTTCATCGTAAT
CTAAAAAATGCATTAAAACTCATGAAATTATGTCAAAAATACCATGTTCATATTCTAAGTGTTCATGATGGCTATTTTGA
TATGGATAAAGCATTCGATCGGCTCAAACTCAATATTTTCATCAGCTTGGCCGAACTAGAATCCGATAATATAGGCGAAC
AAGTCAAAAATGGAATCAAAGAAAAAGCGAAACAAGGTAAAATGATTACAACACATGCACCCTTTGGGTATCAATATCAT
AATGGTACTTTCACGATAGACACAGTAAAAGCACCAACAATAAAAGCTGTATTCAGTTATTATCTTCAAGGCTATGGTTA
TAAAAAAATTGCACAGTACTTAGAAGCTGACGAGAAATTCATCAATCGTAAACCCTATCAAGTACGTAATATTATCATGA
ACCCCAATTATTGTGGTCGAGTCATTAATCAATACGGGCAATATGACAACATGTGTCCTTCTATTGTTTCGACAAGTATA
TATGAACAAGCTCAAGCGATACGATCACAAAAGCAACTCAAACGGACATCATCAGCTAATCAACTCAAACAAAAAATCAA
ATGTCCTTATTGTGGTTCAACGTTGACTAATATAACCATTAGAAAAAAGCACCGTACATTACGTTATTATGTCTGTCCAC
AAAATATGAATGCATCTCGTTTTGTCTGTGAATTCAAAGGAATCAACGCACAATCATTAGAAGCGAGTGTCTTAGCTACA
TGTCAAGATTTCTTTCAAAATCAACATCTGTATTCAAAAATCAACCATACAATCCAAAAACGACTCAAAAAACAAAAAGA
CATAGAAGCTAAAAGTACAGTCACGCAAGAACAACTGATAGAAAAATTAGCCCAAGGTAAAATTGATGCAGAAACATTCA
GAGAACAAACGCAATCATTTCGACAACAGTCAAAACCTATAACATCAATCCATACGCATCAAATTCAAAAGGCTTTACAA
AATGTCATTCAACAACGTTTCACATTAAACATGTTGTACCCTTACATTGATGAAATTCATATTACCAGAAATAAAATACT
TACGGGTATCTATTTCAAAAATGAACCCTTAAACATCGTCAATCAAACAGCACAATCATCGATTGCTTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrA | Staphylococcus aureus COL |
87.082 |
100 |
0.871 |
| ccrA | Staphylococcus aureus N315 |
76.392 |
100 |
0.764 |