Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   I6J12_RS06950 Genome accession   NZ_CP068060
Coordinates   1470090..1470779 (-) Length   229 a.a.
NCBI ID   WP_003038533.1    Uniprot ID   -
Organism   Streptococcus anginosus strain FDAARGOS_1155     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1465090..1475779
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J12_RS06930 (I6J12_06930) nrdR 1465575..1466048 (-) 474 WP_003023591.1 transcriptional regulator NrdR -
  I6J12_RS06935 (I6J12_06935) - 1466215..1466811 (+) 597 WP_003038580.1 hypothetical protein -
  I6J12_RS06940 (I6J12_06940) - 1466858..1467673 (-) 816 WP_003038608.1 endonuclease/exonuclease/phosphatase family protein -
  I6J12_RS06945 (I6J12_06945) - 1467690..1469879 (-) 2190 WP_003038543.1 PTS transporter subunit IIBC -
  I6J12_RS06950 (I6J12_06950) covR 1470090..1470779 (-) 690 WP_003038533.1 DNA-binding response regulator Regulator
  I6J12_RS06955 (I6J12_06955) gndA 1470788..1472212 (-) 1425 WP_003038563.1 NADP-dependent phosphogluconate dehydrogenase -
  I6J12_RS06960 (I6J12_06960) - 1472304..1472840 (-) 537 WP_003038571.1 YceD family protein -
  I6J12_RS06965 (I6J12_06965) - 1473028..1474287 (+) 1260 WP_003038598.1 hypothetical protein -
  I6J12_RS06970 (I6J12_06970) htpX 1474356..1475252 (-) 897 WP_003038595.1 zinc metalloprotease HtpX -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26430.43 Da        Isoelectric Point: 5.8050

>NTDB_id=526802 I6J12_RS06950 WP_003038533.1 1470090..1470779(-) (covR) [Streptococcus anginosus strain FDAARGOS_1155]
MANRILLVEKEKKLAQFIGLELQKEGYRVDLFETGKDALASARANQYDLFLLNFMLDDMTGTEFAAQLSVIKPASVIIVL
DNRDNILQYTEEIQRFAVAYMVEPFIVTDLVEKISAIFRGRDFIDQHCSQMKVPTSYRNLRIDVQNHTVYRGEEVIALTR
REYDLLATLMGSHQALSREQLLERVWKYEGAVETNVVDVYIRYLRSKIDIAGQKSYIKTVRGVGYAMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=526802 I6J12_RS06950 WP_003038533.1 1470090..1470779(-) (covR) [Streptococcus anginosus strain FDAARGOS_1155]
ATGGCGAATCGGATTTTATTAGTTGAGAAAGAAAAAAAATTAGCGCAATTTATTGGCTTAGAATTACAAAAAGAAGGTTA
TCGGGTTGATCTTTTCGAAACGGGAAAAGATGCTTTGGCGTCTGCGAGAGCTAATCAATACGATTTATTCCTGTTGAATT
TTATGCTTGACGATATGACAGGAACAGAATTTGCCGCACAATTAAGTGTGATAAAGCCTGCTTCGGTCATCATTGTATTG
GATAATCGTGATAATATTCTTCAATATACTGAGGAAATCCAACGCTTTGCTGTTGCTTACATGGTAGAACCATTCATTGT
GACGGACTTAGTTGAAAAAATTTCTGCCATTTTTCGTGGGCGTGATTTTATTGACCAGCATTGTAGTCAGATGAAAGTTC
CAACATCTTATCGGAATCTTCGGATTGATGTGCAAAATCATACAGTTTATCGAGGTGAAGAAGTGATTGCTTTGACTCGA
AGAGAGTATGATTTATTAGCAACATTGATGGGAAGTCATCAGGCTTTAAGCCGTGAACAGTTGTTAGAACGCGTGTGGAA
ATACGAAGGAGCTGTTGAAACAAATGTTGTCGATGTTTATATTCGCTATCTTCGTAGTAAAATTGATATAGCGGGGCAAA
AAAGTTATATAAAAACCGTGCGTGGTGTTGGTTATGCTATGCAAGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.978

100

0.45